Santa Cruz Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Mexico which includes heritage elements and mountains

Downtown Querétaro

3 out of top 10 points of interest in this area

Downtown Querétaro is known for its ample dining options, and you can make a stop by Zenea Garden and Plaza de Armas while in the area.

Find hotels in Downtown Querétaro

Top hotels in Santa Cruz

Cinco de Mayo Hotel

Cinco de Mayo Hotel

2.5 out of 5
Calle 5 de Mayo 106, Colonia Centro, Querétaro, QUE
Fully refundableReserve now, pay when you stay
7.4/10 Good! (284 reviews)
"Kind of an unbeatable location in the historic center of Queretaro. Simple, clean, decent value."

Reviewed on 20 Jun 2025

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Cinco de Mayo Hotel
Casa Brunella Hotel Boutique

Casa Brunella Hotel Boutique

3.5 out of 5
Calle Venustiano Carranza No. 37, Colonia Centro, Querétaro, QUE
Fully refundableReserve now, pay when you stay
The price is 1.528.590 ₫ per night from 29 Sept to 30 Sept
1.528.590 ₫
1.826.664 ₫ total
29 Sept - 30 Sept
includes taxes & fees
9.2/10 Wonderful! (217 reviews)
"Excellent!!"

Reviewed on 10 Sept 2025

Casa Brunella Hotel Boutique
Hotel Meson de Isabel

Hotel Meson de Isabel

3 out of 5
C. 5 de Mayo, 119, Querétaro, QUE
Fully refundableReserve now, pay when you stay
7/10 Good! (48 reviews)
"Staff very helpful with figuring out the TV. Smoke alarm needed a new battery."

Reviewed on 3 Dec 2024

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Hotel Meson de Isabel
See all 639 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz holiday package cost?
Explore the best of Santa Cruz from just . Choose from a wonderful selection of rental cars, hotels and flights to suit your budget. You can pick up even better deals when you add a couple of tours or activities to your package.
How do I get a cheap travel package to Santa Cruz?
Just think of all the thrilling things you could do in Santa Cruz with a wad of extra cash in your pocket. Watch your savings stack up when you combine your flights, hotels and other bookings into a Santa Cruz holiday package. You have plenty of choice when you book your trip with Expedia too. In fact, you can pick from more than 550 air carriers and 1null000null000 properties across the globe. Whether you're heading away with the family or travelling with someone special, planning a getaway to Santa Cruz is better with a package.
How far in advance should I book my Santa Cruz holiday?
Savvy travellers will likely want to book as early as possible. You can normally look up international airfares on Expedia up to a year before your flight. If you're purchasing tickets last minute, don't despair. Cheap prices sometimes occur in the last weeks prior to departure.
What does an Expedia Santa Cruz travel package include?
Hotels, car rentals and flights — we bring you the very best bargains. All you'll have to do is pick and choose your favourite combination. After you've made your booking, you can add on the exciting stuff like activities and tours. Our travel packages make it easy to craft an exciting Santa Cruz getaway.
What should I know before booking a Santa Cruz travel package?
An Expedia travel package can be customized for your circumstances and is an easy way to make your money go further. How little or much you include is your call. Rental cars, hotels and flights — mix and match whatever combination suits your style.
Can I choose my airline with a Santa Cruz Expedia holiday package?
Most definitely. Expedia has over 550 partner airlines to pick from around the globe. With such a huge range of choice, finding the right carrier to fly you to Santa Cruz will be a breeze.
If I'm not able to travel, can I cancel my Santa Cruz holiday package?
We get that sometimes life doesn't go according to plan. If you've locked in a Santa Cruz holiday package and have to cancel or amend it, we're here to help. We recommend taking a look at our Customer Service Portal first for information. But in general, if you've booked your package within 24 hours, you may be able to cancel and rebook for free. If it's more than 24 hours, your hotel, airline or car rental company may impose a charge.

Popular places to visit

Pena de Bernal showing tranquil scenes and mountains

Pena de Bernal

Explore the great outdoors at Pena de Bernal, a popular spot to commune with nature in Bernal. Amble around the area's parks or experience its museums.

Pena de Bernal
Tequisquiapan Opal Mine

Tequisquiapan Opal Mine

Find out about the history of Tequisquiapan when you take a trip to Tequisquiapan Opal Mine. Amble around the area's gardens or visit its spas.

Tequisquiapan Opal Mine

Arches Viewpoint

You can learn about the history of Querétaro with a visit to Arches Viewpoint. While you're here, you can savour the top-notch restaurants.

Arches Viewpoint