Photo by Ryan Coleman

Search Family-Friendly Hotels in Sikeston

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Sikeston Family-Friendly Hotels

Top Sikeston Family-Friendly Hotels

Drury Inn & Suites Sikeston, MO
Relax in the serene courtyard, surrounded by lush greenery and comfortable seating.

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1004)
"Very clean, friendly staff, and reasonable rates. "
The price is 2.359.628 ₫
2.712.825 ₫ total
includes taxes & fees
14 Aug - 15 Aug
Drury Inn & Suites Sikeston, MO
Pear Tree Inn Sikeston
Relax in the spacious lobby with a mezzanine level, comfortable seating, and large windows.

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1003)
"Great place to stay with kids "
The price is 2.097.418 ₫
2.411.546 ₫ total
includes taxes & fees
14 Aug - 15 Aug
Pear Tree Inn Sikeston
Pear Tree Inn Cape Girardeau Near the Medical Center
Enjoy meals in the dining area with a view, featuring a long counter, TV, and comfortable seating options.

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1001)
"Excellent place to stay "
The price is 1.835.208 ₫
2.070.410 ₫ total
includes taxes & fees
14 Aug - 15 Aug
Pear Tree Inn Cape Girardeau Near the Medical Center
Drury Plaza Hotel Cape Girardeau Conference Center
Relax in a stylish lounge area with a curved sofa, coffee table, and large flat-screen TV.

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1005)
"Complimentary happy hour with appetizers was amazing! Great breakfast also."
The price is 2.674.280 ₫
3.016.988 ₫ total
includes taxes & fees
14 Aug - 15 Aug
Drury Plaza Hotel Cape Girardeau Conference Center
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Enjoy al fresco dining on the outdoor patio with tables and chairs, surrounded by a metal railing.

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (593)
"This was a great hotel at a great price!"
The price is 2.095.058 ₫
2.267.376 ₫ total
includes taxes & fees
1 Sept - 2 Sept
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Pear Tree Inn Cape Girardeau West
Welcome to our reception area, featuring a modern reception desk and a cozy seating area with armchairs.

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1000)
"We enjoyed the quick check in and how quiet the property was. "
The price is 1.835.208 ₫
2.070.410 ₫ total
includes taxes & fees
10 Aug - 11 Aug
Pear Tree Inn Cape Girardeau West
Super 8 by Wyndham Charleston/Sikeston East MO
Welcome to Simmons Hotel, where guests can enjoy a convenient covered entrance and parking.

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (578)
"Located very close to the expanse of corn fields, quiet, clean rooms, everything is neat, the bathroom is also very clean. Friendly receptionist."
The price is 1.560.149 ₫
1.731.376 ₫ total
includes taxes & fees
10 Aug - 11 Aug
Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Cairo I-57
Relax in the stylish lobby, featuring a reception desk, comfortable seating areas, and beautiful artwork.

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (264)
"The hotel is in need of some serious upkeep and cleaning. It is in fairly poor condition, but it the only hotel in town."
The price is 1.826.555 ₫
2.027.110 ₫ total
includes taxes & fees
7 Sept - 8 Sept
Quality Inn Cairo I-57
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Sikeston Hotel Reviews

Frequently asked questions

What's Sikeston like for family-friendly holidays?
The welcoming destination of Sikeston is a great choice if you've been considering a holiday with the children. The excursions, museums and cafes are just some of the things that make this an attractive spot for a family holiday. Arrange a flight into Cairo, IL (CIR-Cairo Regional), which is located 23.8 mi (38.3 km) from the city centre.
How many family-friendly hotels are there in Sikeston?
Expedia has 16 hotels in Sikeston that are rated for being family-friendly.
When's the best time to book a family-friendly holiday in Sikeston?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Sikeston is 1536 mm.
What's there to see and do with your family in Sikeston?
While you and the family are holidaying in Sikeston, you may want to explore some of the attractions here such as Front Street Studio & Art Gallery, Central Park and Big Oak Tree State Park. Make sure that you have lots of time for activities such as Shawnee National Forest and Mississippi River.