Search Hotels in Skyline, San Diego

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Skyline hotels

Best Western Plus Marina Gateway Hotel

3.5 star property
8.1 km from Skyline
9.2 out of 10, Wonderful, (3511)
"Great friendly staff "
United States
mohammed
The price is 3.061.821 ₫
3.373.974 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Best Western Plus Marina Gateway Hotel

Palihotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 10.8 km from Skyline
8.6 out of 10, Excellent, (2092)
"Room was spotless and location great. "
United States
James
The price is 3.428.100 ₫
3.974.750 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Palihotel San Diego Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
Marina District, 11 km from Skyline
9.0 out of 10, Wonderful, (2694)
"Clean facilities and friendly staff!"
United States
EMMA
The Horton Grand, Downtown/Gaslamp Quarter

Ayres Lodge Alpine

3.0 star property
28.8 km from Skyline
9.2 out of 10, Wonderful, (1004)
"Great hotel."
United States
TOMLINSON,
The price is 2.874.330 ₫
3.109.814 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Ayres Lodge Alpine

Hard Rock Hotel San Diego

4.0 star property
Gaslamp Quarter, 10.8 km from Skyline
9.0 out of 10, Wonderful, (3141)
"Great stay"
United States
Laurence
The price is 4.484.176 ₫
6.410.975 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hard Rock Hotel San Diego

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
Gaslamp Quarter, 10.8 km from Skyline
9.0 out of 10, Wonderful, (1230)
"Very nice clean room and amenities and staff was pleasant and we love the location. "
United States
Arnold
The price is 3.613.703 ₫
4.189.908 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

The Monsaraz San Diego, Tapestry Collection by Hilton

3.5 star property
17.3 km from Skyline
8.6 out of 10, Excellent, (615)
"Great staff, was able to get checked in about an hour early…. Very nice property, lots of seating areas , outdoor patios …. Great Stay"
United States
Jude
The price is 3.353.246 ₫
3.854.388 ₫ total
includes taxes & fees
15 Dec - 16 Dec
The Monsaraz San Diego, Tapestry Collection by Hilton

The Bristol Hotel San Diego

3.5 star property
11.2 km from Skyline
8.6 out of 10, Excellent, (1441)
"So clean, Very Nice staff, convenient location ! "
United States
Cindy
The Bristol Hotel San Diego

The Sofia Hotel

3.5 star property
11.3 km from Skyline
8.4 out of 10, Very good, (1646)
"Great location and history to the hotel "
United States
Stephanie
The Sofia Hotel

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
Gaslamp Quarter, 10.8 km from Skyline
9.4 out of 10, Exceptional, (1000)
"Great location "
United States
Mohammad
The price is 2.965.725 ₫
4.200.471 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Staypineapple, Hotel Z, Gaslamp San Diego

Gaslamp Plaza Suites

3.5 star property
Gaslamp Quarter, 10.9 km from Skyline
9.0 out of 10, Wonderful, (1011)
"very good location, good and quiet AC system (not the noise window AC)."
United States
Henry
The price is 2.978.906 ₫
3.388.506 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Gaslamp Plaza Suites

Bay Club Hotel & Marina

3.5 star property
16.9 km from Skyline
9.2 out of 10, Wonderful, (3184)
"Great stay and location!"
United States
Jason
The price is 3.108.080 ₫
3.572.583 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Bay Club Hotel & Marina

Margaritaville Hotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 10.7 km from Skyline
9.0 out of 10, Wonderful, (1160)
"Amenities and location were great. "
United States
Julie
The price is 4.246.918 ₫
5.993.859 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Margaritaville Hotel San Diego Gaslamp Quarter

Hotel Palmeras Chula Vista

2.0 star property
8.7 km from Skyline
7.2 out of 10, Good, (1981)
"Great stay"
United States
Eleazar
The price is 1.625.929 ₫
1.788.522 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Hotel Palmeras Chula Vista

Marriott Marquis San Diego Marina

4.0 star property
Marina District, 11.3 km from Skyline
9.2 out of 10, Wonderful, (1943)
"Great hotel"
United States
Farzana
The price is 4.191.558 ₫
6.246.279 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Marriott Marquis San Diego Marina

Urban Boutique Hotel

3.0 star property
Little Italy, 11.7 km from Skyline
8.6 out of 10, Excellent, (1278)
"Locations is excellent and the front desk lady was friendly "
Canada
Ju
Urban Boutique Hotel

Legacy Resort Hotel & Spa

4.0 star property
13.2 km from Skyline
9.2 out of 10, Wonderful, (2957)
"Everything was super comfortable and the room was surprisingly affordable for the amenities you get. We will definitely stay there again if we go to San Diego."
United States
Eric
The price is 4.010.978 ₫
4.610.419 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Legacy Resort Hotel & Spa

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
11.3 km from Skyline
8.8 out of 10, Excellent, (725)
"Great little boutique hotel ! Friendly staff as well"
Canada
Caroll
The price is 2.577.892 ₫
2.988.937 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The DEXTRO Little Italy, BW Premier Collection

La Pensione Hotel

3.0 star property
Little Italy, 11.7 km from Skyline
8.6 out of 10, Excellent, (1905)
"Friendly staff, very nice room, great location!"
United States
Lisa
La Pensione Hotel

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
6.8 km from Skyline
8.6 out of 10, Excellent, (1490)
"Good for a short stay "
United States
Sandra
The price is 2.679.697 ₫
2.947.667 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn by Wyndham San Diego Chula Vista
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Skyline

Find the best Skyline areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Skyline Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Skyline?
Travellers will be sure to find plenty to entertain them in San Diego's Skyline neighbourhood.
If I need to cancel my hotel reservation in Skyline, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the top deals on offer in Skyline.
What can I see and do in this San Diego neighbourhood?
A few places to visit in the area around Skyline include Malcolm X Library and Performing Arts Center, Tubman-Chavez Center and Bonita Golf Club. While you're out sightseeing in San Diego, make sure that you visit other sights such as Sweetwater Summit Regional Park or San Diego Voice & Viewpoint.