Search Spa Hotels in Southern Illinois

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check availability on Southern Illinois Spa Hotels

This weekend
Next weekend

Top Southern Illinois Spa Hotels

Walker's Bluff Casino Resort

4.5 star property
9.4 out of 10, Exceptional, (346)
"I had a lovely birthday weekend getaway. I enjoyed the
spa
and ended the night with a lovely dinner at Ruthie's"
Dianah
Walker's Bluff Casino Resort

1895 Washington Hotel

3.0 star property
9.0 out of 10, Wonderful, (362)
"Wonderful place! Such a cute vibe. Nice rooms and facility, had jacuzzi tub in our room. Love the shared kitchen/cooking area (has pots and pans to use) and love that it has a fridge. Beds were very nice! James was wonderful host and greeter. Would come back again."
Rebecca
1895 Washington Hotel

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1001)
"Nice rooms. Loved the jacuzzi. Bed wasn't the most comfortable, but not a bad night's sleep. I'd stay again. "
Terry
The price is 2.878.040 ₫
3.246.833 ₫ total
includes taxes & fees
18 Jul - 19 Jul
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1000)
"One of the most wonderful experiences I’ve ever had at a hotel. I was there for a solo trip for myself and had an amazing experience. All the staff were phenomenal. The
spa
was beyond amazing. The room service staff were very respectful and well dressed. The vallet service was exceptional as well like I said one of the best hotel experiences I’ve ever had."
Anonymous traveller
The price is 12.951.180 ₫
15.143.685 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Four Seasons Hotel St Louis

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1215)
"We liked that the hotel had valet parking, which made it easier than trying to find a spot to park. We drove a larger van, and trying to find a spot to park would have been hard. The hotel had a great pool and
hot tub
. The rooms were great, clean and comfortable. "
Allen
The price is 3.952.072 ₫
4.751.938 ₫ total
includes taxes & fees
20 Jul - 21 Jul
21C Museum Hotel St Louis

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (536)
"Top quality Concierge floor worth the cost"
Norma E.
The price is 15.148.956 ₫
17.646.716 ₫ total
includes taxes & fees
6 Jul - 7 Jul
The Ritz-Carlton, St. Louis

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very good, (1005)
"Our stay was amazing and definitely going back! The
spa
was great and all the staff were perfect very polite!"
Charlotte
The price is 4.425.641 ₫
5.606.422 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Ameristar Casino Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.