Southern Minnesota Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Southern Minnesota

Find the best Southern Minnesota areas and neighborhoods for the activities you enjoy most. Learn more about Southern Minnesota
Rochester showing skyline and a city

Downtown Rochester

2 out of top 10 points of interest in this area

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Art Center are top sights worth seeing.

Find hotels in Downtown Rochester

Top hotels in Southern Minnesota

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
8.2/10 Very Good! (1,535 reviews)
"x"

Reviewed on 25 Aug 2025

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Kahler Grand Hotel
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is 1.897.776 ₫ per night from 31 Aug to 1 Sept
1.897.776 ₫
2.184.815 ₫ total
31 Aug - 1 Sept
includes taxes & fees
7.2/10 Good! (1,002 reviews)
Okay stay
"Hotel was clean. Sink drain not working. Fire alarm for faulty sensor sent everyone outdoors at 2330 hrs. Mgmt was apologetic."

Reviewed on 21 Aug 2025

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3 out of 5
4165 Maine Ave SE, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is 1.926.770 ₫ per night from 7 Sept to 8 Sept
1.926.770 ₫
2.218.194 ₫ total
7 Sept - 8 Sept
includes taxes & fees
9.2/10 Wonderful! (109 reviews)
"Easy access to Mayo Clinic & numerous restaurants."

Reviewed on 20 Aug 2025

Spark by Hilton Rochester South
See all 1,177 properties in Southern Minnesota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Lake Shetek State Park

Lake Shetek State Park

Commune with nature and explore the great outdoors at Lake Shetek State Park during your travels in The Lakes. Amble around the area's parks or experience its museums.

Lake Shetek State Park
Niagara Cave

Niagara Cave

Commune with nature and explore the great outdoors at Niagara Cave during your travels in Harmony. Amble within the natural setting or visit the churches in this family-friendly area.

Niagara Cave

Mayo Clinic

If Mayo Clinic is what brings you to town, hopefully you'll have a chance to explore more of Rochester.

Mayo Clinic

Frequently asked questions

How much does a Southern Minnesota holiday package cost?
Live it up in Southern Minnesota from as low as . We offer a great selection of rental cars, hotels and flights to suit every style and budget. You can pick up even better deals when you add some activities or tours to your holiday package.
How do I get a cheap travel package to Southern Minnesota?
Imagine all the amazing things you could do in Southern Minnesota with extra cash in your wallet. Watch your savings stack up when you bundle your flights, hotels and other bookings into a Southern Minnesota holiday package. You have loads of choice when you book with Expedia too. In fact, you can select from more than 550 airlines and 1null000null000 hotel options worldwide. Whether you're taking off with the entire family or travelling on your own, planning a getaway to Southern Minnesota is better with a package.
What are the top hotels in Southern Minnesota?
For properties in Rochester with cosy beds and friendly service, look up Kahler Inn and Suites - Mayo Clinic Area and Kahler Grand Hotel. If you're stopping by Lake City as well, you can look forward to a great night's sleep at Pet - Friendly Wabasha Studio: Boat or Peaceful Condo In Wabasha With Beautiful River Bluff Location - Lower Unit.
How far in advance should I book my Southern Minnesota holiday?
It can be hard to know when the best time is to book your holiday to Southern Minnesota. But typically the earlier you book, the more affordable the prices. In some cases, you can secure your flights and hotels up to a year before your departure date. If you're thinking of a last-minute getaway, no need to fret! There are great bargains popping up on Expedia all the time.
What does an Expedia Southern Minnesota travel package include?
Much of that depends on you. You can choose from a variety of Southern Minnesota bundles, such as a rental car, flight and hotel. You can also book a flight with a hotel, or a flight with a rental car. Once you've made your booking, you can add the fun stuff like activities and tours. Whatever your dream Southern Minnesota break looks like, you're sure to save!
What should I know before booking a Southern Minnesota travel package?
Bundling your bookings into a Southern Minnesota holiday package is the most convenient way to organise your trip. Not only that, you'll get great discounts when you combine your hotels, flights and car rentals. Once you've booked, why not add on an activity or a tour?
Can I choose my airline with a Southern Minnesota Expedia holiday package?
Yes, you sure can. We offer more than 550 airline partners all over the world, so fly with the carrier that best fits your budget and travel needs.
If I'm not able to travel, can I cancel my Southern Minnesota holiday package?
We totally get it — life sometimes gets in the way of your plans. If you've booked a Southern Minnesota holiday package and have to cancel or change it, we can help. We suggest browsing our Customer Service Portal first for information. But generally, if you've booked your package in the last 24 hours, you may be able to cancel or amend your itinerary at no cost. If it's been longer than 24 hours, your airline, hotel or car rental company may impose a fee.