Midtown Travel Guide
St. Louis
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theatre scene or attend a baseball game.
Gateway Arch
Find out about the history of Gateway Arch, one of the top monuments in St. Louis. Experience the area's fascinating museums or attend a baseball game.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Top hotels in Midtown
Element St. Louis Midtown
Nice property Convenient location
Reviewed on 25 Mar 2026
Residence Inn by Marriott St Louis Downtown
Pulled out the sofa bed and stains all over. Third person (that I paid for was not able to sleep on the mattress). Took pictures showed to front desk and they took the pictures from my phone and said “ok” . Absolutely disgusting.
Reviewed on 9 Mar 2026
Drury Plaza Hotel St. Louis at the Arch
My kids loved it
Reviewed on 24 Mar 2026
Pear Tree Inn St. Louis Near Union Station
Air conditioning in multiple rooms didnt work. Fromt desk reset unit but onky lasted a few hours. Room was mid 70 by morning.
Reviewed on 25 Mar 2026
Clayton Plaza Hotel & Extended Stay
Stay was wonderful. Would definitely recommend.
Reviewed on 23 Mar 2026
21C Museum Hotel St Louis
Overall a great hotel, nice location, easy valet. It was inconvenient that an elevator was down, we waited for 5 cycles to run before we were able to get to the lobby around breakfast.
Reviewed on 24 Mar 2026
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Enterprise Center.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and Enterprise Center.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Enterprise Center are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
