Midtown Travel Guide

St. Louis

Midtown
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Photo by Karissa Krull
Photo by Linda Garrison
Photo by Sophie R

Popular places to visit


Top hotels in Midtown

Element St. Louis Midtown

Element St. Louis Midtown

3 out of 5
3763 Forest Park Avenue St. Louis MO
The price is 3.447.265 ₫ per night from 28 Dec to 29 Dec
3.447.265 ₫
4.030.852 ₫ total
28 Dec - 29 Dec
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (646 reviews)
The room was spacious, and the staff were as friendly and helpful as any I have ever met.

Reviewed on 16 Dec 2025

Element St. Louis Midtown
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is 2.605.185 ₫ per night from 23 Dec to 24 Dec
2.605.185 ₫
3.072.269 ₫ total
23 Dec - 24 Dec
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (4,011 reviews)
Everything was great

Reviewed on 16 Dec 2025

Hyatt Regency St. Louis at The Arch
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

2.5 out of 5
333 Washington Ave St. Louis MO
The price is 2.567.818 ₫ per night from 28 Dec to 29 Dec
2.567.818 ₫
3.002.524 ₫ total
28 Dec - 29 Dec
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,180 reviews)
Breakfast area was small and crowded - did not help to have children and some teenagers on their own and not exactly being quiet.

Reviewed on 19 Dec 2025

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
The price is 2.107.831 ₫ per night from 25 Dec to 26 Dec
2.107.831 ₫
2.506.823 ₫ total
25 Dec - 26 Dec
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,157 reviews)
Good

Reviewed on 16 Dec 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
The price is 3.552.262 ₫ per night from 26 Dec to 27 Dec
3.552.262 ₫
4.153.625 ₫ total
26 Dec - 27 Dec
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the pool in their ...
9.4/10 Exceptional! (3,290 reviews)
All is perfect except room cleanse

Reviewed on 18 Dec 2025

Drury Plaza Hotel St. Louis at the Arch
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
The price is 3.528.842 ₫ per night from 29 Dec to 30 Dec
3.528.842 ₫
4.257.814 ₫ total
29 Dec - 30 Dec
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
9/10 Wonderful! (1,501 reviews)
Hotel was comfortable, clean and unique. All staff was wonderful

Reviewed on 16 Dec 2025

21C Museum Hotel St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Midtown

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The Gate

While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Chaifetz Arena.

The Gate
St. Louis showing interior views

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Downtown West
Lafayette Square featuring a house and a park

Lafayette Square

The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Gateway Arch are a few top sights nearby.

Lafayette Square
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The Grove

While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.

The Grove
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Shaw

Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.

Shaw
Central West End

Central West End

4.5/5(2 area reviews)

If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Central West End


Midtown Travel Guide

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