Midtown Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Midtown

Find the best Midtown areas and neighborhoods for the activities you enjoy most. Learn more about Midtown
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

4 out of top 10 points of interest in this area
4.5/5(18 area reviews)

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Find hotels in Downtown St. Louis

Top hotels in Midtown

Element St. Louis Midtown

Element St. Louis Midtown

3 out of 5
3763 Forest Park Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is 3.506.625 ₫ per night from 12 Feb to 13 Feb
3.506.625 ₫
4.100.261 ₫ total
12 Feb - 13 Feb
includes taxes & fees
9/10 Wonderful! (666 reviews)
The room was clean, the car service was efficient and the lobby was clean. The from desk staff were pretty condescending with us

Reviewed on 1 Feb 2026

Element St. Louis Midtown
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is 3.483.248 ₫ per night from 22 Feb to 23 Feb
3.483.248 ₫
4.202.802 ₫ total
22 Feb - 23 Feb
includes taxes & fees
9/10 Wonderful! (1,592 reviews)
Hotel was very quiet and staff helpful and courteous. The coffee shop was great for coffee and breakfast and the rooms were clean with hot water and great water pressure. The only thing I would change was the mattress - bed was very firm, kind of felt like lying on a table. Gallery was a fun feature ...

Reviewed on 3 Feb 2026

21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is 2.691.724 ₫ per night from 12 Feb to 13 Feb
2.691.724 ₫
3.142.264 ₫ total
12 Feb - 13 Feb
includes taxes & fees
8.8/10 Excellent! (3,084 reviews)
Staff always pleasant

Reviewed on 2 Feb 2026

Clayton Plaza Hotel & Extended Stay
See all 1,849 properties in Midtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Midtown holiday package cost?
Starting from a low , a package is your gateway to low-priced travel. Build your own Midtown trip by selecting from our great range of hotels, flights and rental cars.
How do I get a cheap travel package to Midtown?
Bundle your bookings with Expedia to save big bucks on your next trip. With over 550 partner airlines and 1null000null000 properties throughout the world, your Midtown holiday package can be tailored exactly to suit your travel style. With all that extra cash, why not add one or two awesome tours and activities? It's an easy way to unlock even more savings. The holiday you've always dreamed of in Midtown is much closer than you thought!
Where should I stay in Midtown?
A trip to Midtown isn't complete until you've seen Busch Stadium and Gateway Arch. Book a hotel within walking distance so you can easily access these terrific tourist attractions.
What are the top hotels in Midtown?
Book a room at Element St. Louis Midtown. It's one of this neighbourhood's most in-demand hotels. Another reputable option in Midtown is Residence Inn by Marriott St Louis Downtown.
How far in advance should I book my Midtown holiday?
While prices fluctuate, we generally advise booking your holiday as soon as possible. Most international fares are available on Expedia up to 12 months in advance. If you're booking late, you might still get lucky. Cheap journeys to Midtown occasionally appear only weeks before departure.
What does an Expedia Midtown travel package include?
With Expedia, you can select a combination of car rentals, hotels and flights to build your ideal Midtown package. Once you've made your booking, you can add on the fun things like tours and experiences. Remember — the more you bundle, the bigger the savings!
What should I know before booking a Midtown travel package?
You'll land big savings when you bundle your hotels, flights and rental cars into a package. Plus, booking everything in one spot makes trip planning easier. So why waste time or money? Whether you're putting together an upscale romantic escape or an affordable family break, browse our holiday packages today.
Can I choose my airline with a Midtown Expedia holiday package?
With a holiday package, you're the boss. Whether you're looking to fly to Midtown in economy or business class, simply select from the available airline options. Expedia has access to over 550 airline partners worldwide.
If I'm not able to travel, can I cancel my Midtown holiday package?
Don't stress if you're rethinking your Midtown holiday package — it's possible to cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur charges from your airline, hotel or car rental company. We understand life can occasionally throw a spanner in the travel works, so head to our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.

Popular places to visit

Union Station, St. Louis, MO

St. Louis Union Station

4.5/5(4 reviews)

You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's acclaimed art galleries or attend a baseball game.

St. Louis Union Station
Gateway Arch showing a city, city views and skyline

Gateway Arch

5/5(16 reviews)

Find out about the history of Gateway Arch, one of the top monuments in St. Louis. Experience the area's acclaimed art galleries or attend a baseball game.

Gateway Arch
St. Louis Zoo

St. Louis Zoo

Why not visit the animals who live at St. Louis Zoo during your holiday in St. Louis? Amble around the area's lush forest or attend a sporting event.

St. Louis Zoo