Midtown Travel Guide

St. Louis

A historic building with a large lawn, a flagpole with flags, and a clear blue sky.
Midtown
A cathedral interior with Gothic architecture, including pointed arches and ribbed vaults.
Midtown
A highway with multiple lanes, vehicles, and a bridge overhead.

Stay near popular Midtown attractions


Top hotels in Midtown

Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown

3 out of 5
3763 Forest Park Avenue St. Louis MO
The price is 3.790.080 ₫ per night from 2 Jul to 3 Jul
3.790.080 ₫
4.431.703 ₫ total
2 Jul - 3 Jul
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (764 reviews)
"The absolute worst staff I have ever had the displeasure of working with. The facility itself is nice, pool was cold, breakfast great, however— they charge $28 for valet parking (or $42 for self parking!) and kept us waiting at check in for over 5 minutes. At checkout I thought we were all good, ..."

Reviewed on 23 Jun 2026

Element by Marriott St. Louis Midtown
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
525 S Jefferson Ave St. Louis MO
The price is 3.105.760 ₫ per night from 13 Jul to 14 Jul
3.105.760 ₫
3.693.650 ₫ total
13 Jul - 14 Jul
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a 24-hour fitness centre and parking (surcharge). Our guests praise the breakfast and the ...
7.8/10 Good! (1,000 reviews)
"Fire alarm went off two days at 4am. Very inconvenient"

Reviewed on 21 Jun 2026

Residence Inn by Marriott St Louis Downtown
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is 4.184.880 ₫ per night from 28 Jun to 29 Jun
4.184.880 ₫
4.935.187 ₫ total
28 Jun - 29 Jun
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (4,136 reviews)
"Nice hotel and close to ballpark."

Reviewed on 25 Jun 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is 2.614.629 ₫ per night from 26 Jul to 27 Jul
2.614.629 ₫
3.052.594 ₫ total
26 Jul - 27 Jul
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (3,247 reviews)
"Very nice older hotel renovated"

Reviewed on 26 Jun 2026

Clayton Plaza Hotel & Extended Stay
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
The price is 2.737.070 ₫ per night from 29 Jun to 30 Jun
2.737.070 ₫
3.575.524 ₫ total
29 Jun - 30 Jun
includes taxes & fees
Stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants and a casino. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (2,202 reviews)
"Basic rooms but the bedding and bed was very comfortable; a great nights sleep!"

Reviewed on 25 Jun 2026

Hollywood Casino & Hotel St. Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
The price is 4.474.137 ₫ per night from 29 Jun to 30 Jun
4.474.137 ₫
5.231.363 ₫ total
29 Jun - 30 Jun
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.6/10 Exceptional! (3,518 reviews)
"Probably one of the best hotels we’ve stayed in. Every single member of the staff was friendly and helpful. The food was excellent. Location was excellent. I can’t say enough good things. We will definitely come back to St. Louis and will definitely stay at this hotel!"

Reviewed on 26 Jun 2026

Drury Plaza Hotel St. Louis at the Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Central West End

The abundant dining options and forests are just a few top-rate features of the neighbourhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.



Midtown Travel Guide

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