Midtown Travel Guide

St. Louis

Midtown
Photo by throwingsofas
Photo by Karissa Krull
Photo by Linda Garrison
Photo by Sophie R

Popular places to visit


Top hotels in Midtown

Element St. Louis Midtown

Element St. Louis Midtown

3 out of 5
3763 Forest Park Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is 3.564.135 ₫ per night from 30 Sept to 1 Oct
3.564.135 ₫
4.167.507 ₫ total
30 Sept - 1 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and ...
9/10 Wonderful! (592 reviews)
"Great place to stay!"

Reviewed on 18 Sept 2025

Element St. Louis Midtown
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
The price is 3.167.856 ₫ per night from 1 Oct to 2 Oct
3.167.856 ₫
3.704.143 ₫ total
1 Oct - 2 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (3,091 reviews)
"great location for our trip goals"

Reviewed on 25 Sept 2025

Drury Plaza Hotel St. Louis at the Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
The price is 2.605.482 ₫ per night from 5 Oct to 6 Oct
2.605.482 ₫
3.035.072 ₫ total
5 Oct - 6 Oct
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,968 reviews)
"We loved our stay at Clayton Plaza Hotel! Especially the Jacuzzi in our room! The staff was very friendly and awesome!"

Reviewed on 24 Sept 2025

Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St, St. Louis, MO
The price is 3.300.125 ₫ per night from 2 Oct to 3 Oct
3.300.125 ₫
3.891.804 ₫ total
2 Oct - 3 Oct
includes taxes & fees
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (4,010 reviews)
"Everyone & everything"

Reviewed on 25 Sept 2025

Hyatt Regency St. Louis at The Arch
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln, St. Ann, MO
The price is 2.375.826 ₫ per night from 20 Oct to 21 Oct
2.375.826 ₫
2.796.922 ₫ total
20 Oct - 21 Oct
includes taxes & fees
Stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.2/10 Wonderful! (2,689 reviews)
"The staff was very nice and helpful, but the room was not very clean"

Reviewed on 24 Sept 2025

Pear Tree Inn St. Louis Airport
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road, St. Louis, MO
The price is 3.352.927 ₫ per night from 5 Oct to 6 Oct
3.352.927 ₫
3.922.523 ₫ total
5 Oct - 6 Oct
includes taxes & fees
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge) and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,014 reviews)
"Beautiful hotel and we loved the music in the dining room."

Reviewed on 22 Sept 2025

Renaissance St. Louis Airport Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Midtown

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The Gate

While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium.

The Gate
St. Louis showing interior views

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Downtown West
Lafayette Square featuring a house and a park

Lafayette Square

The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby.

Lafayette Square
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Shaw

Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.

Shaw
Central West End

Central West End

4.5/5(2 area reviews)

If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Central West End
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The Grove

While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.

The Grove