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Our top choices for Midtown hotels

Courtyard
Element St. Louis Midtown

Element St. Louis Midtown

Element St. Louis Midtown
3.0 star property
Midtown
9.0 out of 10, Wonderful, (643)
"Everything was excellent. The staff were very friendly and helpful. The accommodations were excellent and it was a great location near every where we were going."
United States
Angela
The price is 3.577.752 ₫
4.183.430 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Element St. Louis Midtown
BBQ/picnic Area
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.8 out of 10, Good, (1002)
"Ok"
United States
Shamari
The price is 2.893.770 ₫
3.441.531 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Residence Inn by Marriott St Louis Downtown
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 3.4 km from Midtown
8.4 out of 10, Very good, (4009)
"Arch view room is big and comfortable fantastic. . "
United States
Tim
The price is 2.213.734 ₫
2.610.635 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Hyatt Regency St. Louis at The Arch
Lobby
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
17.3 km from Midtown
9.4 out of 10, Exceptional, (2755)
"The room was clean and staff were very friendly."
United States
Denise
The price is 2.367.367 ₫
2.786.964 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Pear Tree Inn St. Louis Airport
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 3 km from Midtown
8.8 out of 10, Excellent, (1149)
"Really nice hotel!"
United States
DARIN
The price is 2.296.601 ₫
2.731.323 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Property amenity
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 3.4 km from Midtown
9.4 out of 10, Exceptional, (3279)
"Our stay was very enjoyable. Location was great and kids loved the indoor pool!"
United States
Christy
The price is 3.551.182 ₫
4.152.361 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Drury Plaza Hotel St. Louis at the Arch
Exterior
Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG

Holiday Inn Express Troy by IHG
2.5 star property
29.4 km from Midtown
9.4 out of 10, Exceptional, (701)
"Great breakfast ! "
United States
Jeanette
The price is 2.446.551 ₫
2.715.182 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Troy by IHG
Front of property
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 3.4 km from Midtown
8.8 out of 10, Excellent, (1014)
"My second time staying there as always it was lovely "
United States
Nina
The price is 2.714.882 ₫
3.201.633 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hilton Pennywell St. Louis at the Arch
Free daily buffet breakfast
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West, 2.5 km from Midtown
7.6 out of 10, Good, (586)
"Everything great….very nice staff and security….delicious breakfast!!"
Canada
Derek
The price is 2.135.602 ₫
2.497.138 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru By Hilton St. Louis Downtown
Lobby
Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia
2.5 star property
21.2 km from Midtown
8.6 out of 10, Excellent, (476)
"Breakfast was great and a very good atten"
United States
John
The price is 2.293.970 ₫
2.545.847 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn St. Louis - Columbia
Lobby sitting area
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
24.5 km from Midtown
7.4 out of 10, Good, (1001)
"Clean lobby, super friendly staff, effortless check in. There’s even a small market with food and essentials right next to the check in desk. "
United States
Jen
The price is 1.685.752 ₫
1.955.270 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Front of property – evening/night
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
25.8 km from Midtown
8.4 out of 10, Very good, (2218)
"Front staff was very friendly and very helpful. Check-in and check out was smooth and very easy. "
United States
James
The price is 2.761.972 ₫
3.604.322 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hollywood Casino & Hotel St. Louis
Exterior
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
27.4 km from Midtown
9.4 out of 10, Exceptional, (1005)
"Love this hotel. "
United States
Lisa
The price is 2.935.861 ₫
3.374.096 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Country Inn & Suites by Radisson, St. Charles Historic District
Exterior
Best Western Plus St. Louis Airport Hotel

Best Western Plus St. Louis Airport Hotel

Best Western Plus St. Louis Airport Hotel
2.5 star property
16 km from Midtown
9.2 out of 10, Wonderful, (1002)
"Room was nice and comfortable, pool was awesome, and breakfast left us all happy"
United States
Letez
The price is 2.884.563 ₫
3.567.955 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Best Western Plus St. Louis Airport Hotel
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 3.1 km from Midtown
8.8 out of 10, Excellent, (1243)
"Great hospitality"
United States
Alejandro
The price is 2.820.110 ₫
3.353.929 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Embassy Suites by Hilton St. Louis Downtown
Exterior
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
9.8 km from Midtown
8.8 out of 10, Excellent, (3032)
"Clean room, good breakfast and good location "
United States
Martin
The price is 2.365.473 ₫
2.761.406 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Clayton Plaza Hotel & Extended Stay
Exterior
Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
27.8 km from Midtown
9.2 out of 10, Wonderful, (817)
"Always a good stay here!"
United States
Chelsie
The price is 3.051.612 ₫
3.508.743 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Edwardsville by IHG
Breakfast, dinner and brunch served
The Principal Hotel

The Principal Hotel

The Principal Hotel
3.5 star property
21.3 km from Midtown
9.8 out of 10, Exceptional, (190)
"Great place. Very nice rooms, new and clean."
United States
Jeff
The price is 2.967.693 ₫
3.293.637 ₫ total
includes taxes & fees
15 Dec - 16 Dec
The Principal Hotel
Reception
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
23.2 km from Midtown
8.0 out of 10, Very good, (1039)
"Everything was clean and friendly staff overall good experience "
United States
dennis
The price is 2.236.095 ₫
2.582.821 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Indoor pool, open 6:00 AM to 10:00 PM, pool loungers
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 3.5 km from Midtown
8.8 out of 10, Excellent, (1167)
"The room was clean and the staff were extremely friendly and personable! "
United States
Shannon
The price is 2.504.426 ₫
2.928.401 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Central West End

If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

Top Midtown Hotel Reviews

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Frequently asked questions

What is Midtown like?
Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 30 Midtown hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.
What are the top things to see and do in Midtown?
Explore Midtown's landmarks such as Washington Avenue Historic District, Samuel Cupples House and Scott Joplin House State Historic Site and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighbourhood. St. Louis Union Station and Gateway Arch are some popular places to visit in the area around Midtown. While you're out sightseeing, .ZACK Theater and The MOTO Museum are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.