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Check availability on Tenderloin Luxury Hotels

Tonight
7 Dec - 8 Dec
Tomorrow
8 Dec - 9 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Top Tenderloin Luxury Hotels

Room (Private Apartment) | Egyptian cotton sheets, premium bedding, minibar, in-room safe
The Clift Royal Sonesta San Francisco

The Clift Royal Sonesta San Francisco

4.0 star property
Union Square
9.2 out of 10, Wonderful, (1367)
"The hotel room was clean and above all else, the staff was incredible... We will only stay at this hotel when we come into town!"
United States
Jennie
The price is 3.928.087 ₫
5.651.318 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The Clift Royal Sonesta San Francisco
Exterior
Hotel Spero, Vignette Collection by IHG

Hotel Spero, Vignette Collection by IHG

4.0 star property
Union Square
8.8 out of 10, Excellent, (1289)
"Good location and great price. "
United States
Brienne
The price is 2.952.656 ₫
4.406.049 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Spero, Vignette Collection by IHG
Front of property – evening/night
Hotel Nikko San Francisco

Hotel Nikko San Francisco

4.5 star property
Union Square
9.4 out of 10, Exceptional, (2635)
"The entire hotel was fabulous!"
United States
Nicole
The price is 4.011.130 ₫
5.932.993 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel Nikko San Francisco
Lobby
Staypineapple, An Elegant Hotel, Union Square

Staypineapple, An Elegant Hotel, Union Square

4.0 star property
Union Square
8.6 out of 10, Excellent, (1002)
"Stayed for two night and had an Amazing experience with staff. Loved that the hotel was dog friendly and provided what I needed for my pups stay! Overall had a wonderful experience and a plus was there amazing bedding with European duvets which provided extra comfort with my stay ! "
United States
Valerie
The price is 2.728.570 ₫
4.294.910 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Staypineapple, An Elegant Hotel, Union Square
Exterior
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 star property
Union Square
8.8 out of 10, Excellent, (2794)
"Clean room, friendly staff and great location"
Canada
Christian Middleton
Handlery Union Square Hotel
Property entrance
Monarch Hotel

Monarch Hotel

2.0 star property
Downtown San Francisco
6.2 out of 10, (997)
"Disappointed that they wouldn’t accommodate in any way due to covid. We would of wish to reschedule or have some options, instead of losing our money for something not our fault. "
United States
Jason
Monarch Hotel
Fusion cuisine
Hotel Bijou - Union Square

Hotel Bijou - Union Square

4.0 star property
Union Square
7.4 out of 10, Good, (858)
"Room was very clean and quiet. Staff very pleasant and helpful. "
United States
REBECCA
Hotel Bijou - Union Square
In-room safe, desk, blackout curtains, iron/ironing board
Adante Hotel

Adante Hotel

3.0 star property
Union Square
6.2 out of 10, (997)
"It was all ok until my friend pointed out a very large cockroach dead on the bathroom floor "
United States
Ramon
Adante Hotel
Lobby
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

4.0 star property
Union Square
8.6 out of 10, Excellent, (1458)
"It was such a great place to stay!!! Everyone was very friendly and very very welcoming💛💛💛"
United States
Isabel
The price is 3.338.874 ₫
5.076.651 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Parc 55 San Francisco - A Hilton Hotel
Lobby sitting area
The Marker Union Square San Francisco

The Marker Union Square San Francisco

4.0 star property
Union Square
9.0 out of 10, Wonderful, (1098)
"Very courteous staff, rooms & amenities clean, comfortable bed"
Australia
Inna
The price is 3.475.171 ₫
4.090.102 ₫ total
includes taxes & fees
12 Dec - 13 Dec
The Marker Union Square San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Tenderloin Hotel Reviews

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Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Tenderloin?
Use Expedia to arrange your flight to San Francisco International Airport (SFO) airport or Oakland, CA (OAK-Oakland Intl.) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to get what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa or several swimming pools, Expedia can help you find the best luxury hotel experience that Tenderloin offers. During your visit, you might want to enjoy the art and opera which Tenderloin is known for.
What's there to see and do in Tenderloin?
Take in some sights and attractions while you're in Tenderloin by visiting Great American Music Hall, Van Ness Avenue and SOMA Pilipinas. If you have extra time while you're in the area, you might want to see Oracle Park and Pier 39.