Photo by Ryan Watts
Search Hotels by Independent in Upstate South Carolina from 1.409.336 ₫
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Top Upstate South Carolina Independent Hotels
Lakeside Lodge Clemson
Seneca
9.0 out of 10, Wonderful, (1009)
"Overall great stay."
Daniel
The price is 2.874.221 ₫
3.567.989 ₫ total
includes taxes & fees
4 Dec - 5 Dec
Inn @ Clemson
Clemson
8.0 out of 10, Very good, (1020)
"Very good location. "
Jennifer
Hotel Hartness
Greenville
9.8 out of 10, Exceptional, (623)
"Beautiful location, friendly staff"
Andrew
The price is 4.226.925 ₫
5.540.929 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Greenville Inn and Suites
Greenville
6.0 out of 10, (160)
"Front desk ladies are nice"
Robert
Clemson University's James F. Martin Inn
Clemson
9.6 out of 10, Exceptional, (959)
"Great place to stay!"
Mindi
The price is 3.928.981 ₫
4.361.169 ₫ total
includes taxes & fees
4 Dec - 5 Dec
Horizon Inn & Suites
Anderson
4.6 out of 10, (235)
"Motel for crackheads"
Ryan
The price is 1.198.388 ₫
1.409.336 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
The Abernathy of Clemson
Clemson
9.6 out of 10, Exceptional, (555)
"location is amazing! "
colleen
The Inn at Patrick Square
Clemson
9.8 out of 10, Exceptional, (781)
"Clean room. Nice front desk concierge. Very cute hotel"
Anisha
The price is 3.928.981 ₫
4.361.168 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Upstate South Carolina Hotel Reviews
DoubleTree by Hilton Greenville Woodruff Road
10/10 Excellent