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Check prices for these dates

Tonight
6 Mar - 7 Mar
Tomorrow
7 Mar - 8 Mar
This weekend
6 Mar - 8 Mar
Next weekend
13 Mar - 15 Mar

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Our top choices for 21c Museum Hotel hotels

Terrace/patio

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,004 reviews)
"Excellent Hotel"
United States
Nairobi
The price is 2.843.340 ₫
3.345.474 ₫ total
includes taxes & fees
15 Mar - 16 Mar
Homewood Suites by Hilton Louisville Downtown, KY
Room (Asleep in the Cyclone) | Premium bedding, down duvets, minibar, in-room safe

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,008 reviews)
"Great room, super kind staff"
United States
Rachel
The price is 4.687.831 ₫
5.646.646 ₫ total
includes taxes & fees
30 Mar - 31 Mar
21c Museum Hotel Louisville
Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (453 reviews)
"Great hotel & location"
United States
Ana
The price is 4.587.180 ₫
5.397.275 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Hotel Distil, Autograph Collection
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,004 reviews)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The price is 4.207.263 ₫
4.950.507 ₫ total
includes taxes & fees
2 Apr - 3 Apr
The Grady
Dining

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,003 reviews)
"Great stay "
United States
Sarah
The price is 2.702.705 ₫
3.180.002 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Cambria Hotel Louisville Downtown-Whiskey Row
Interior entrance

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from 21c Museum Hotel
9.8 out of 10, Exceptional, (120 reviews)
"Warm greeting by Carol who shared all the information and details about the property. SUPER charming and convenient location. Highly recommend."
United States
Kelly
The price is 4.851.774 ₫
5.482.667 ₫ total
includes taxes & fees
15 Mar - 16 Mar
Market Street Inn
Interior

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,186 reviews)
"Beautiful old hotel with a fantastic bar in the lobby"
United States
Karen
The Brown Hotel
Property amenity

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (553 reviews)
"The hotel is so clean and easy access to everything downtown."
United States
Erin
The price is 2.645.089 ₫
3.112.212 ₫ total
includes taxes & fees
22 Mar - 23 Mar
Towneplace Suites By Marriott Louisville Downtown
2 restaurants, breakfast served

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (936 reviews)
"Always a great place to stay."
United States
Christopher
The price is 2.354.731 ₫
2.770.576 ₫ total
includes taxes & fees
4 Apr - 5 Apr
Tempo By Hilton Louisville Downtown Nulu
Lounge

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (125 reviews)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
The price is 3.090.040 ₫
4.954.501 ₫ total
includes taxes & fees
20 Mar - 21 Mar
Stellar Suites
Interior entrance

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (721 reviews)
"Great stay. Great location and good food. "
United States
Bryson
The price is 2.331.177 ₫
2.742.865 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Moxy Louisville Downtown
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1,784 reviews)
"Amazing stay! "
United States
Erin
The price is 4.798.034 ₫
5.645.366 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Omni Louisville Hotel
4 restaurants, breakfast, lunch, dinner served; American cuisine

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (4,095 reviews)
"Rooms were clean and staff were friendly! "
United States
Amy
The price is 3.307.265 ₫
3.891.327 ₫ total
includes taxes & fees
22 Mar - 23 Mar
Galt House Hotel Trademark Collection by Wyndham
Exterior

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (78 reviews)
"i love this place"
United States
THANH
The price is 3.762.050 ₫
4.426.428 ₫ total
includes taxes & fees
3 Apr - 4 Apr
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,159 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is 3.004.664 ₫
3.535.287 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Embassy Suites Louisville Downtown
Lobby lounge

AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (627 reviews)
"Nice hotel, super overpriced"
United States
Kevin
The price is 2.784.807 ₫
3.276.603 ₫ total
includes taxes & fees
3 Apr - 4 Apr
AC Hotel Louisville Downtown
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1,049 reviews)
"Spotless room and courteous staff "
United States
Mary
The price is 3.535.515 ₫
4.159.886 ₫ total
includes taxes & fees
15 Mar - 16 Mar
Hotel Genevieve part of JdV by Hyatt
Restaurant

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,003 reviews)
"Great staff, good bar. "
United States
Edward
The price is 2.631.995 ₫
3.096.806 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Aloft Louisville Downtown
Exterior

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.7 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,002 reviews)
"Very nice hotel. Great stay!"
United States
Brad
The price is 4.392.566 ₫
5.168.294 ₫ total
includes taxes & fees
4 Apr - 5 Apr
Louisville Marriott Downtown
Lobby

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville, 0.6 km from 21c Museum Hotel
8.8 out of 10, Excellent, (1,003 reviews)
"Everything was just excellent on the day I stayed."
United States
Peggy
The price is 3.539.443 ₫
4.164.508 ₫ total
includes taxes & fees
4 Apr - 5 Apr
Hyatt Regency Louisville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top 21c Museum Hotel Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent
"It was great"
Gary 1-night trip
Posted 4 hours ago
Galt House Hotel Trademark Collection by Wyndham

Hotels near other 21c Museum Hotel attractions

Louisville Science Center

Louisville Science Center

You can spend an afternoon browsing the exhibits at Louisville Science Center in Louisville. Stroll along the area's riverfront or experience its fascinating museums.
See properties
Kentucky Center for the Performing Arts

Kentucky Center for the Performing Arts

Enjoy an outing to Kentucky Center for the Performing Arts during your stay in Louisville. Stroll along the riverfront or attend a sporting event in the area.
See properties

Frequently asked questions

What's the area like around 21c Museum Hotel?
21c Museum Hotel is located in a family-friendly area of Louisville known for its stunning river views and great live music scene. If you're looking for a convenient place to stay, take a look at the 309 hotels and other accommodation options you'll find within a mile.
How many hotels are there near 21c Museum Hotel?
Expedia has 309 hotels and other accommodation options within a mile from 21c Museum Hotel.
If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best deals available near 21c Museum Hotel.
What can I see and do near 21c Museum Hotel?
You might want to spend some time browsing the exhibits at Louisville Science Center, Muhammad Ali Center or Louisville Slugger Museum. Explore landmarks like Belle of Louisville, Whiskey Row and Thomas Edison House. You can watch performances at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall if you're interested in local theatre.