A calm body of water, a sandy beach, and a forested area in the distance.

Find hotels in Cape Girardeau, MO from 1.819.015 ₫

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
23 Aug - 24 Aug
Tomorrow
24 Aug - 25 Aug
Next weekend
28 Aug - 30 Aug
In two weeks
4 Sep - 6 Sep

Filter by

Star rating

Guest rating

Our top choices for Cape Girardeau hotels

1. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
United States
Taylor
3.267.112 ₫
3.702.095 ₫ total
includes taxes & fees
3 Sept - 4 Sept
Courtyard by Marriott Cape Girardeau Downtown

2. The Riverview

The Riverview
Cape Girardeau
United States
Alyssa
2.985.059 ₫
3.367.565 ₫ total
includes taxes & fees
24 Aug - 25 Aug
The Riverview

3. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Joy
2.611.339 ₫
2.945.956 ₫ total
includes taxes & fees
6 Sept - 7 Sept
Drury Plaza Hotel Cape Girardeau Conference Center

4. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
ELAINE
2.663.832 ₫
3.005.175 ₫ total
includes taxes & fees
21 Sept - 22 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

5. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
United States
Cheryl
2.350.179 ₫
2.651.331 ₫ total
includes taxes & fees
2 Sept - 3 Sept
Drury Inn & Suites Cape Girardeau

6. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Bonnie
1.880.091 ₫
2.121.006 ₫ total
includes taxes & fees
30 Aug - 31 Aug
Pear Tree Inn Cape Girardeau West

7. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
United States
Heather
2.641.633 ₫
2.980.132 ₫ total
includes taxes & fees
30 Aug - 31 Aug
Fairfield Inn & Suites by Marriott Cape Girardeau

8. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
United States
Rebekah
2.762.550 ₫
3.116.543 ₫ total
includes taxes & fees
30 Aug - 31 Aug
Hampton Inn Cape Girardeau I 55 East

9. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Gwendolyn
2.334.248 ₫
2.656.700 ₫ total
includes taxes & fees
30 Aug - 31 Aug
Tru By Hilton Cape Girardeau

10. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
2.298.208 ₫
2.736.338 ₫ total
includes taxes & fees
30 Aug - 31 Aug
Candlewood Suites Cape Girardeau by IHG

11. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
United States
Stephen
1.612.402 ₫
1.819.015 ₫ total
includes taxes & fees
6 Sept - 7 Sept
Quality Inn Cape Girardeau North

12. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
United States
Joshua
1.828.120 ₫
2.135.505 ₫ total
includes taxes & fees
5 Sept - 6 Sept
Town House Inn Cape Giradreau

13. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
United States
Jamie
2.245.715 ₫
2.374.282 ₫ total
includes taxes & fees
20 Sept - 21 Sept
Drury Inn & Suites Jackson MO

14. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
Jackson
United States
VICTORIA
2.178.681 ₫
2.357.726 ₫ total
includes taxes & fees
21 Sept - 22 Sept
Comfort Suites Jackson-Cape Girardeau

15. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
United States
Shawn
2.308.654 ₫
2.498.541 ₫ total
includes taxes & fees
24 Aug - 25 Aug
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

16. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
United States
JANEEN
2.634.843 ₫
2.868.059 ₫ total
includes taxes & fees
26 Aug - 27 Aug
EC Reed's Mercantile and Hotel

17. Makanda Inn

Makanda Inn
Makanda
United States
Michele
6.840.721 ₫
7.798.422 ₫ total
includes taxes & fees
24 Aug - 25 Aug
Makanda Inn

18. Hotel 7 Inn Anna

Hotel 7 Inn Anna
Anna
United States
Dorothy J
1.833.343 ₫
2.126.365 ₫ total
includes taxes & fees
24 Aug - 25 Aug
Hotel 7 Inn Anna
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Cape Girardeau attractions

A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
See properties
A cable-stayed bridge over a river with a rocky shoreline in the foreground.

Riverfront Bridge Park

8.8/10 (129 reviews)
Enjoy panoramic views of the Mississippi River and Bill Emerson Memorial Bridge from this peaceful riverside park. Stroll along the well-maintained walking paths and find perfect spots for memorable photographs.
See properties

Century Casino & Hotel Cape Girardeau

8.4/10 (176 reviews)
Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your time in Cape Girardeau? While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Hunter Valley Winery

7.4/10 (48 reviews)
Sip award-winning Chambourcin and Chardonnay at this picturesque Missouri estate with lake views. Bring a picnic basket and enjoy live weekend music on the deck overlooking the sculpture garden.
See properties

Riverfront Park

8.0/10 (2 reviews)
This riverside haven features terraced seating overlooking the Mississippi and a flood wall adorned with historical murals. Stroll the riverfront trail while watching paddle boats dock at this picturesque park.
See properties

Cape Splash Family Aquatic Center

8.6/10 (21 reviews)
This 3.5-acre water park thrills with a 265-foot free-fall slide and 700-foot lazy river. Families can splash in the pirate ship playground or relax in shaded lounge areas during summer months.
See properties

Show Me Center

8.6/10 (40 reviews)
The Show Me Centre hosts Southeast Missouri State basketball and major concerts in a versatile arena setting. Catch Redhawks games or enjoy performances by renowned artists in this regional entertainment hub.
See properties

Cape Rock Park

8.6/10 (36 reviews)
Perched on a limestone bluff, Cape Rock Park offers panoramic views of the Mississippi River and passing barges. Bring binoculars to spot wildlife at this historic former trading post.
See properties

Learn more about Cape Girardeau

Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.

See all hotels in Cape Girardeau
A nighttime view of a bridge with its cables illuminated against a starry sky.

Top Cape Girardeau Hotel Reviews

Frequently asked questions

What's the weather like in Cape Girardeau?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cape Girardeau is 1495 mm.

Explore a world of travel with Expedia