A calm body of water, a sandy beach, and a forested area in the distance.

Find hotels in Cape Girardeau, MO from 1.819.015 ₫

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
23 Aug - 24 Aug
Tomorrow
24 Aug - 25 Aug
Next weekend
28 Aug - 30 Aug
In two weeks
4 Sep - 6 Sep

Filter by

Star rating

Guest rating

Our top choices for Cape Girardeau hotels

A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A lobby with seating areas, a reception desk, and a bar.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

1. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
United States
Taylor
3.267.112 ₫
3.702.095 ₫ total
includes taxes & fees
3 Sept - 4 Sept
Courtyard by Marriott Cape Girardeau Downtown
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A hotel room with two beds, a desk, a chair, and a view of the city.
A modern outdoor seating area with a glass-top table and a fire feature, overlooking a sunset view.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

2. The Riverview

The Riverview
Cape Girardeau
United States
Alyssa
2.985.059 ₫
3.367.565 ₫ total
includes taxes & fees
24 Aug - 25 Aug
The Riverview
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

3. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Joy
2.611.339 ₫
2.945.956 ₫ total
includes taxes & fees
6 Sept - 7 Sept
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A hotel room with a bed, a desk, a chair, a kitchenette, and a bathroom.
A buffet with labeled containers of omelets and other dishes.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

4. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
ELAINE
2.663.832 ₫
3.005.175 ₫ total
includes taxes & fees
21 Sept - 22 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

5. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
United States
Cheryl
2.350.179 ₫
2.651.331 ₫ total
includes taxes & fees
2 Sept - 3 Sept
Drury Inn & Suites Cape Girardeau
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

6. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Bonnie
1.880.091 ₫
2.121.006 ₫ total
includes taxes & fees
30 Aug - 31 Aug
Pear Tree Inn Cape Girardeau West
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.
A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

7. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
United States
Heather
2.641.633 ₫
2.980.132 ₫ total
includes taxes & fees
30 Aug - 31 Aug
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.
An outdoor patio with stone walls, wicker furniture, and large windows.

8. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
United States
Rebekah
2.762.550 ₫
3.116.543 ₫ total
includes taxes & fees
30 Aug - 31 Aug
Hampton Inn Cape Girardeau I 55 East
A modern retail area with a display of local items and snacks.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

9. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Gwendolyn
2.334.248 ₫
2.656.700 ₫ total
includes taxes & fees
30 Aug - 31 Aug
Tru By Hilton Cape Girardeau
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A modern living room with a sofa, a coffee table, a blue armchair, and a desk with a lamp. A kitchen area with wooden cabinets and a microwave is visible in the background.
A hotel patio with a gazebo, outdoor seating, and a view of the road.
A hotel room with a kitchenette, a bed, a desk, and a TV.

10. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
2.298.208 ₫
2.736.338 ₫ total
includes taxes & fees
30 Aug - 31 Aug
Candlewood Suites Cape Girardeau by IHG
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

11. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
United States
Stephen
1.612.402 ₫
1.819.015 ₫ total
includes taxes & fees
6 Sept - 7 Sept
Quality Inn Cape Girardeau North
A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.
A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.
A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.
A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

12. Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
Cape Girardeau
United States
Joshua
1.828.120 ₫
2.135.505 ₫ total
includes taxes & fees
5 Sept - 6 Sept
Town House Inn Cape Giradreau
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
A restaurant with a brick wall, a flat-screen TV, and a bar area.
A hotel room with two beds, a brick wall, and a wooden headboard.
A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

13. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
United States
Jamie
2.245.715 ₫
2.374.282 ₫ total
includes taxes & fees
20 Sept - 21 Sept
Drury Inn & Suites Jackson MO
A spacious lobby with large windows, comfortable seating, and a modern ceiling design.
A room with large windows, two red upholstered chairs, a small table, and a potted plant.
A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.
A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

14. Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
Jackson
United States
VICTORIA
2.178.681 ₫
2.357.726 ₫ total
includes taxes & fees
21 Sept - 22 Sept
Comfort Suites Jackson-Cape Girardeau
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
An outdoor patio with tables and chairs, a stone wall, and large windows.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

15. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
United States
Shawn
2.308.654 ₫
2.498.541 ₫ total
includes taxes & fees
24 Aug - 25 Aug
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A living room with a blue wall, a fireplace, a sofa, and a chair.
A bar area with stools and a counter where a bartender is serving drinks.
A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.
A brick building with a sign reading "Mercantile & Hotel".

16. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
United States
JANEEN
2.634.843 ₫
2.868.059 ₫ total
includes taxes & fees
26 Aug - 27 Aug
EC Reed's Mercantile and Hotel
A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.
A rustic building with a thatched roof, surrounded by dense greenery and a gravel path leading to it.
A cozy living room with a brown leather sofa, a wooden coffee table, and a window with a view of trees.
A stone building with a patio area, string lights, and outdoor seating.

17. Makanda Inn

Makanda Inn
Makanda
United States
Michele
6.840.721 ₫
7.798.422 ₫ total
includes taxes & fees
24 Aug - 25 Aug
Makanda Inn
An indoor swimming pool with clear water, marked lanes, and a lifeguard warning sign.
A hotel room with two beds, a television, a desk, and a large cityscape painting on the wall.
A hotel room with a treadmill, exercise bike, and dumbbells.
A modern living room with two sofas, a coffee table, and a TV.

18. Hotel 7 Inn Anna

Hotel 7 Inn Anna
Anna
United States
Dorothy J
1.833.343 ₫
2.126.365 ₫ total
includes taxes & fees
24 Aug - 25 Aug
Hotel 7 Inn Anna
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Cape Girardeau attractions

A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
See properties
A cable-stayed bridge over a river with a rocky shoreline in the foreground.

Riverfront Bridge Park

8.8/10 (129 reviews)
Enjoy panoramic views of the Mississippi River and Bill Emerson Memorial Bridge from this peaceful riverside park. Stroll along the well-maintained walking paths and find perfect spots for memorable photographs.
See properties

Century Casino & Hotel Cape Girardeau

8.4/10 (176 reviews)
Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your time in Cape Girardeau? While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Hunter Valley Winery

7.4/10 (48 reviews)
Sip award-winning Chambourcin and Chardonnay at this picturesque Missouri estate with lake views. Bring a picnic basket and enjoy live weekend music on the deck overlooking the sculpture garden.
See properties

Riverfront Park

8.0/10 (2 reviews)
This riverside haven features terraced seating overlooking the Mississippi and a flood wall adorned with historical murals. Stroll the riverfront trail while watching paddle boats dock at this picturesque park.
See properties

Cape Splash Family Aquatic Center

8.6/10 (21 reviews)
This 3.5-acre water park thrills with a 265-foot free-fall slide and 700-foot lazy river. Families can splash in the pirate ship playground or relax in shaded lounge areas during summer months.
See properties

Show Me Center

8.6/10 (40 reviews)
The Show Me Centre hosts Southeast Missouri State basketball and major concerts in a versatile arena setting. Catch Redhawks games or enjoy performances by renowned artists in this regional entertainment hub.
See properties

Cape Rock Park

8.6/10 (36 reviews)
Perched on a limestone bluff, Cape Rock Park offers panoramic views of the Mississippi River and passing barges. Bring binoculars to spot wildlife at this historic former trading post.
See properties

Learn more about Cape Girardeau

Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.

See all hotels in Cape Girardeau
A nighttime view of a bridge with its cables illuminated against a starry sky.

Top Cape Girardeau Hotel Reviews

Frequently asked questions

What's the weather like in Cape Girardeau?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cape Girardeau is 1495 mm.

Explore a world of travel with Expedia