
Find hotels in Defiance, MO from 1.906.002 ₫
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Our top choices for Defiance hotels

Baymont by Wyndham Warrenton
Baymont by Wyndham WarrentonWarrenton
7.6 out of 10, Good, (1,001 reviews)
The price is 1.947.071 ₫
2.224.041 ₫ total
includes taxes & fees
19 Apr - 20 Apr

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by WyndhamFenton
8.0 out of 10, Very good, (1,195 reviews)
The price is 2.350.042 ₫
2.714.200 ₫ total
includes taxes & fees
12 Apr - 13 Apr

Quality Inn Foristell
Quality Inn ForistellForistell
8.2 out of 10, Very good, (966 reviews)
The price is 2.394.350 ₫
2.704.418 ₫ total
includes taxes & fees
14 Apr - 15 Apr

Hampton Inn St. Louis Wentzville
Hampton Inn St. Louis WentzvilleWentzville
9.0 out of 10, Wonderful, (688 reviews)
The price is 3.561.118 ₫
4.075.699 ₫ total
includes taxes & fees
29 Apr - 30 Apr

Holiday Inn Express & Suites St Peters by IHG
Holiday Inn Express & Suites St Peters by IHGSt. Peters
9.2 out of 10, Wonderful, (400 reviews)
The price is 3.001.734 ₫
3.612.350 ₫ total
includes taxes & fees
3 May - 4 May

Super 8 by Wyndham Warrenton
Super 8 by Wyndham WarrentonWarrenton
7.4 out of 10, Good, (640 reviews)
The price is 1.387.644 ₫
1.585.037 ₫ total
includes taxes & fees
22 Apr - 23 Apr

Wingate by Wyndham St. Louis/Fenton Route 66
Wingate by Wyndham St. Louis/Fenton Route 66Fenton
7.8 out of 10, Good, (1,192 reviews)
The price is 2.237.710 ₫
2.584.687 ₫ total
includes taxes & fees
19 Apr - 20 Apr

WoodSpring Suites St Peters-OFallon
WoodSpring Suites St Peters-OFallonSt. Peters
8.8 out of 10, Excellent, (76 reviews)
The price is 2.343.014 ₫
2.774.093 ₫ total
includes taxes & fees
13 Apr - 14 Apr

Drury Inn & Suites Southwest St. Louis
Drury Inn & Suites Southwest St. LouisValley Park
9.6 out of 10, Exceptional, (1,013 reviews)
The price is 2.922.478 ₫
3.418.949 ₫ total
includes taxes & fees
3 May - 4 May

Best Western Plus Washington Hotel
Best Western Plus Washington HotelWashington
9.2 out of 10, Wonderful, (672 reviews)
The price is 3.396.054 ₫
3.866.408 ₫ total
includes taxes & fees
22 Apr - 23 Apr

Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
9.0 out of 10, Wonderful, (1,001 reviews)
The price is 2.160.838 ₫
2.548.708 ₫ total
includes taxes & fees
14 Apr - 15 Apr

Comfort Inn & Suites St. Louis - O'Fallon
Comfort Inn & Suites St. Louis - O'FallonO'Fallon
7.6 out of 10, Good, (1,002 reviews)
The price is 2.077.253 ₫
2.450.120 ₫ total
includes taxes & fees
6 May - 7 May

Best Western Plus Fenton
Best Western Plus FentonFenton
9.2 out of 10, Wonderful, (258 reviews)
The price is 2.588.601 ₫
2.989.523 ₫ total
includes taxes & fees
14 Apr - 15 Apr

Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. PetersSt. Charles
8.0 out of 10, Very good, (1,005 reviews)
The price is 3.000.637 ₫
3.448.542 ₫ total
includes taxes & fees
26 Apr - 27 Apr

Holiday Inn Express & Suites Wentzville St Louis West by IHG
Holiday Inn Express & Suites Wentzville St Louis West by IHGWentzville
9.4 out of 10, Exceptional, (891 reviews)
The price is 3.660.009 ₫
4.357.135 ₫ total
includes taxes & fees
26 Apr - 27 Apr

Super 8 by Wyndham St Charles
Super 8 by Wyndham St CharlesSt. Charles
8.0 out of 10, Very good, (1,001 reviews)
The price is 2.215.754 ₫
2.546.500 ₫ total
includes taxes & fees
26 Apr - 27 Apr

Fairfield Inn & Suites Wentzville
Fairfield Inn & Suites WentzvilleWentzville
9.0 out of 10, Wonderful, (669 reviews)
The price is 3.366.569 ₫
3.853.039 ₫ total
includes taxes & fees
27 Apr - 28 Apr

The Wildwood Hotel
The Wildwood HotelWildwood
9.2 out of 10, Wonderful, (1,629 reviews)
The price is 2.321.953 ₫
2.704.797 ₫ total
includes taxes & fees
13 Apr - 14 Apr

Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. PetersSt. Peters
9.4 out of 10, Exceptional, (1,012 reviews)
The price is 3.133.126 ₫
3.601.529 ₫ total
includes taxes & fees
27 Apr - 28 Apr

Drury Plaza Hotel St. Louis Chesterfield
Drury Plaza Hotel St. Louis ChesterfieldChesterfield
9.8 out of 10, Exceptional, (1,131 reviews)
The price is 3.580.073 ₫
4.152.455 ₫ total
includes taxes & fees
19 Apr - 20 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

Top Defiance Hotel Reviews

Ameristar Casino Resort and Spa
2/10 Terrible
More cheap stays in Defiance

Relax Inn Saint Charles
3800 Harry S Truman Blvd St. Charles MO
The price is 1.658.538 ₫ per night from 26 Apr to 27 Apr
1.658.538 ₫
1.906.002 ₫ total
26 Apr - 27 Apr
includes taxes & fees
6.8/10 (1,003 reviews)
Hotels in Defiance with star rating

4 Star Hotels
7 properties













































































