A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Find hotels in Defiance, MO from 1.980.478 ₫

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Check prices for these dates

Next weekend
17 Jul - 19 Jul
In two weeks
24 Jul - 26 Jul

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Our top choices for Defiance hotels

Reception

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
7.8 out of 10, Good, (1,424 reviews)
"Will definitely stay again!"
United States
Trevor
The price is 2.478.480 ₫
2.862.270 ₫ total
includes taxes & fees
12 Jul - 13 Jul
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Indoor pool

Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.6 out of 10, Good, (1,005 reviews)
"Excellent place to stay!"
United States
Steven
The price is 2.145.915 ₫
2.451.171 ₫ total
includes taxes & fees
28 Jul - 29 Jul
Baymont by Wyndham Warrenton
Lobby

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (1,009 reviews)
"Good location."
United States
Kristin
The price is 2.198.715 ₫
2.483.448 ₫ total
includes taxes & fees
26 Jul - 27 Jul
Quality Inn Foristell
Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
7.8 out of 10, Good, (1,279 reviews)
"Enjoyed my stay."
United States
Robert
The price is 2.344.508 ₫
2.707.808 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Wingate by Wyndham St. Louis/Fenton Route 66
Exterior

Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
St. Peters
9.4 out of 10, Exceptional, (425 reviews)
"Front desk (older lady) was super friendly and helpful. Hotel was clean and orderly."
United States
Stefan
The price is 2.895.758 ₫
3.357.632 ₫ total
includes taxes & fees
19 Jul - 20 Jul
Holiday Inn Express & Suites St Peters by IHG
Lobby

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.0 out of 10, Wonderful, (707 reviews)
"Was great. Thanks"
United States
Melissa
The price is 3.388.701 ₫
3.858.036 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Best Western Plus Washington Hotel
Lobby

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.4 out of 10, Exceptional, (1,012 reviews)
"Great location and clean hotel!"
United States
Admir
The price is 2.892.077 ₫
3.324.441 ₫ total
includes taxes & fees
2 Aug - 3 Aug
Drury Inn & Suites St. Louis St. Peters
Indoor pool

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,015 reviews)
"We liked that it was very close to the I terstate"
United States
Michelle
The price is 2.875.930 ₫
3.305.428 ₫ total
includes taxes & fees
19 Jul - 20 Jul
Hampton Inn St. Charles St. Peters
Room, Accessible | Desk, iron/ironing board, free WiFi, bed sheets

Super 8 by Wyndham O'Fallon MO/St. Louis Area

Super 8 by Wyndham O'Fallon MO/St. Louis Area
2.0 star property
O'Fallon
7.0 out of 10, Good, (1,005 reviews)
"Clean room, friendly staff"
United States
Shelly
The price is 1.786.292 ₫
2.106.931 ₫ total
includes taxes & fees
9 Aug - 10 Aug
Super 8 by Wyndham O'Fallon MO/St. Louis Area
Premium bedding, desk, iron/ironing board, free WiFi

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,048 reviews)
"Easy access to the building was clean and friendly staff good breakfast and good internet ."
United States
Joseph
The price is 2.201.080 ₫
2.596.174 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Sleep Inn & Suites O'Fallon MO - Technology Drive
Exterior

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,006 reviews)
"Always a nice time at the Frontenac!!!"
United States
Megan
The price is 2.810.783 ₫
3.274.431 ₫ total
includes taxes & fees
12 Jul - 13 Jul
Hilton St. Louis Frontenac
Front of property – evening/night

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
Riverport
8.6 out of 10, Excellent, (2,212 reviews)
"Check-in was easy. The hotel staff were polite. Room was wonderful. Very close to the concert venue. Great stay!"
United States
Derek
The price is 2.470.165 ₫
3.262.553 ₫ total
includes taxes & fees
19 Jul - 20 Jul
Hollywood Casino & Hotel St. Louis
Lobby

Economy Inn Wentzville

Economy Inn Wentzville
2.0 star property
Wentzville
6.4 out of 10, (550 reviews)
"Room was clean but basic"
United States
James
The price is 1.838.830 ₫
2.086.152 ₫ total
includes taxes & fees
12 Jul - 13 Jul
Economy Inn Wentzville
Free daily buffet breakfast

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.2 out of 10, Wonderful, (376 reviews)
"Was a good place to stay"
Canada
Blake
The price is 2.500.809 ₫
2.888.134 ₫ total
includes taxes & fees
19 Jul - 20 Jul
Best Western Plus Fenton
Exterior

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (936 reviews)
"We have stay here before and requested to stay again. Great hotel."
United States
Steve
The price is 2.990.988 ₫
3.584.440 ₫ total
includes taxes & fees
9 Aug - 10 Aug
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Lobby

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
Chesterfield
9.6 out of 10, Exceptional, (1,216 reviews)
"Had a great stay"
United States
Madeleine
The price is 3.572.321 ₫
4.143.462 ₫ total
includes taxes & fees
2 Aug - 3 Aug
Drury Plaza Hotel St. Louis Chesterfield
Property entrance

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1,674 reviews)
"Very nice hotel for the price! Would definitely stay there again in the future!"
United States
Lori
The price is 2.553.347 ₫
2.974.342 ₫ total
includes taxes & fees
28 Jul - 29 Jul
The Wildwood Hotel
Free daily buffet breakfast

SpringHill Suites by Marriott St. Louis Airport/Earth City

SpringHill Suites by Marriott St. Louis Airport/Earth City
3.0 star property
Bridgeton
8.8 out of 10, Excellent, (1,003 reviews)
"Breakfast was decent plenty of options, staff are very friendly, room was clean, everything functioned as it should, overall a good experience."
United States
Devin
The price is 3.234.162 ₫
3.838.207 ₫ total
includes taxes & fees
19 Jul - 20 Jul
SpringHill Suites by Marriott St. Louis Airport/Earth City
Premium bedding, desk, iron/ironing board, free cots/infant beds

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.2 out of 10, Very good, (1,008 reviews)
"Great location, of staying away from busy intersections!!"
United States
David
The price is 2.222.357 ₫
2.554.134 ₫ total
includes taxes & fees
12 Jul - 13 Jul
Super 8 by Wyndham St Charles
Lobby

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Days Inn and Suites by Wyndham St. Louis/Westport Plaza
2.5 star property
Westport
4.4 out of 10, (1,005 reviews)
"Nice facilities"
United States
Roger
The price is 1.786.292 ₫
2.071.885 ₫ total
includes taxes & fees
4 Aug - 5 Aug
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

A glass of red wine on a wooden table with a vineyard in the background.
Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

7.8/10 (7 reviews)
This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
See properties

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Top Defiance Hotel Reviews

Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur

8/10 Good
"Good place to stay, friendly staff, family oriented and clean."
Shayna 2-night trip
Posted 7 hours ago
Drury Plaza Hotel St. Louis Creve Coeur

More cheap stays in Defiance

Motel 6 Maryland Heights, MO

Motel 6 Maryland Heights, MO

12330 Dorsett Rd Maryland Heights MO
The price is 1.707.485 ₫ per night from 12 Jul to 13 Jul
1.707.485 ₫
1.980.478 ₫ total
12 Jul - 13 Jul
includes taxes & fees
6.2/10 (1,006 reviews)

Hotels in Defiance with star rating

Frequently asked questions

What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.