Find hotels in Defiance, MO from 1.902.238 ₫
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Our top choices for Defiance hotels

WoodSpring Suites St Peters-OFallon
WoodSpring Suites St Peters-OFallonSt. Peters
9.2 out of 10, Wonderful, (30)
The price is 2.338.386 ₫
2.768.614 ₫ total
includes taxes & fees
9 Jan - 10 Jan

Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. PetersSt. Charles
8.0 out of 10, Very good, (1002)
The price is 2.486.309 ₫
2.857.440 ₫ total
includes taxes & fees
5 Feb - 6 Feb

Quality Inn Foristell
Quality Inn ForistellForistell
8.2 out of 10, Very good, (920)
The price is 1.942.962 ₫
2.194.575 ₫ total
includes taxes & fees
14 Jan - 15 Jan


Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
9.0 out of 10, Wonderful, (1002)
The price is 2.057.254 ₫
2.426.531 ₫ total
includes taxes & fees
25 Jan - 26 Jan

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by WyndhamFenton
8.0 out of 10, Very good, (1063)
The price is 2.233.290 ₫
2.579.581 ₫ total
includes taxes & fees
1 Feb - 2 Feb

Comfort Inn & Suites St. Louis - O'Fallon
Comfort Inn & Suites St. Louis - O'FallonO'Fallon
7.6 out of 10, Good, (1005)
The price is 1.951.370 ₫
2.301.640 ₫ total
includes taxes & fees
24 Jan - 25 Jan

Holiday Inn Express St. Louis West - O'Fallon by IHG
Holiday Inn Express St. Louis West - O'Fallon by IHGO'Fallon
8.6 out of 10, Excellent, (856)
The price is 2.496.030 ₫
2.944.067 ₫ total
includes taxes & fees
11 Jan - 12 Jan

Hampton Inn St. Louis Wentzville
Hampton Inn St. Louis WentzvilleWentzville
9.0 out of 10, Wonderful, (640)
The price is 3.131.861 ₫
3.584.415 ₫ total
includes taxes & fees
23 Jan - 24 Jan

Baymont by Wyndham Warrenton
Baymont by Wyndham WarrentonWarrenton
7.4 out of 10, Good, (1002)
The price is 1.920.629 ₫
2.193.838 ₫ total
includes taxes & fees
21 Jan - 22 Jan

Super 8 by Wyndham Warrenton
Super 8 by Wyndham WarrentonWarrenton
7.4 out of 10, Good, (623)
The price is 1.518.637 ₫
1.734.663 ₫ total
includes taxes & fees
14 Jan - 15 Jan

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport WestMaryland Heights
7.4 out of 10, Good, (1003)
The price is 1.872.811 ₫
2.172.235 ₫ total
includes taxes & fees
15 Jan - 16 Jan

Drury Plaza Hotel St. Louis Chesterfield
Drury Plaza Hotel St. Louis ChesterfieldChesterfield
9.6 out of 10, Exceptional, (1048)
The price is 3.415.357 ₫
3.961.331 ₫ total
includes taxes & fees
13 Jan - 14 Jan

Best Western Plus St. Louis West-Westport
Best Western Plus St. Louis West-WestportMaryland Heights
8.0 out of 10, Very good, (1030)
The price is 1.987.628 ₫
2.305.410 ₫ total
includes taxes & fees
1 Feb - 2 Feb

Hilton Garden Inn St. Louis/O'Fallon MO
Hilton Garden Inn St. Louis/O'Fallon MOO'Fallon
8.8 out of 10, Excellent, (722)
The price is 2.468.180 ₫
2.926.644 ₫ total
includes taxes & fees
23 Jan - 24 Jan

Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St LouisSt. Charles
8.4 out of 10, Very good, (1000)
The price is 1.986.314 ₫
2.282.812 ₫ total
includes taxes & fees
11 Jan - 12 Jan

Comfort Inn Near Six Flags St. Louis
Comfort Inn Near Six Flags St. LouisPacific
8.4 out of 10, Very good, (882)
The price is 2.388.569 ₫
2.734.314 ₫ total
includes taxes & fees
30 Jan - 31 Jan

Holiday Inn Express & Suites Wentzville St Louis West by IHG
Holiday Inn Express & Suites Wentzville St Louis West by IHGWentzville
9.4 out of 10, Exceptional, (857)
The price is 2.890.140 ₫
3.468.036 ₫ total
includes taxes & fees
18 Jan - 19 Jan

Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. PetersSt. Peters
9.4 out of 10, Exceptional, (1000)
The price is 2.889.877 ₫
3.322.084 ₫ total
includes taxes & fees
15 Jan - 16 Jan

Wingate by Wyndham St. Louis/Fenton Route 66
Wingate by Wyndham St. Louis/Fenton Route 66Fenton
7.8 out of 10, Good, (1135)
The price is 2.076.960 ₫
2.398.639 ₫ total
includes taxes & fees
11 Jan - 12 Jan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

Top Defiance Hotel Reviews

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
10/10 Excellent
More cheap stays in Defiance

Relax Inn Saint Charles
3800 Harry S Truman Blvd St. Charles MO
The price is 1.655.262 ₫ per night from 9 Jan to 10 Jan
1.655.262 ₫
1.902.238 ₫ total
9 Jan - 10 Jan
includes taxes & fees
6.6/10 (999 reviews)
Hotels in Defiance with star rating

4 Star Hotels
6 properties







































































