South Main Travel Guide
Houston
Visit South Main
Top hotels in South Main
Wyndham Houston at Reliant Park & Medical Center
"Very convenient stay if you have a concert to go to at the stadium. It was walkable and easy to get to. The place is nice and clean, just a little outdated. Over all comfortable."
Reviewed on 13 Oct 2026
Club Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
"The front desk staff rushed our check-in process, she did not explain parking just pointed at a QR code and told me to follow the directions. The valet parking staff actually explained parking once we checked in. The water in the shower was not hot. After calling the front desk we were told we had ..."
Reviewed on 14 Oct 2026
The Whitehall Houston
Grand Tuscany Hotel
"The property is lovely and esthetically pleasing. The staff are friendly and accommodating. There is always someone to assist no matter the time!"
Reviewed on 13 Oct 2026
Hyatt Regency Houston West
Where to stay in South Main
Downtown Houston
Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.
The Galleria
Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.
