South Main Travel Guide

Houston

A city skyline with modern buildings and a park with a lake.
A modern urban street with a metro train, buildings, and a clear blue sky.

Top hotels in South Main

Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
The price is 2.868.580 ₫ per night from 7 Sept to 8 Sept
2.868.580 ₫
3.356.238 ₫ total
7 Sept - 8 Sept
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the restaurant and the helpful staff ...
8.6/10 Excellent! (4,501 reviews)
"Location was perfect for our one night stay. Walkable to Jones Hall and very convenient to food locations. We ate at table 7 bistro convenient and it was good. Room was clean and sufficient, carpets are aged and need updating but that aside everything else was fine."

Reviewed on 29 Aug 2026

Club Quarters Hotel Downtown, Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
The price is 2.590.178 ₫ per night from 6 Sept to 7 Sept
2.590.178 ₫
3.051.896 ₫ total
6 Sept - 7 Sept
includes taxes & fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and the clean ...
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Grand Tuscany Hotel

Grand Tuscany Hotel

4 out of 5
12801 Northwest Fwy Houston TX
The price is 2.240.466 ₫ per night from 31 Aug to 1 Sept
2.240.466 ₫
2.621.345 ₫ total
31 Aug - 1 Sept
includes taxes & fees
Stay at this family-friendly hotel in Houston. Enjoy free Wi-Fi, an outdoor pool and breakfast (surcharge). Our guests praise the pool and the helpful staff ...
8.2/10 Very good! (282 reviews)
"Very clean room, everything was accessible, super convenient area with lots of stores and restaurants even walking distance! 10/10 will come again."

Reviewed on 26 Aug 2026

Grand Tuscany Hotel
Marriott Marquis Houston

Marriott Marquis Houston

4 out of 5
1777 Walker Street Houston TX
The price is 5.658.926 ₫ per night from 17 Sept to 18 Sept
5.658.926 ₫
7.352.684 ₫ total
17 Sept - 18 Sept
includes taxes & fees
Stay at this spa hotel in Houston. Enjoy 2 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their reviews. ...
Marriott Marquis Houston
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
The price is 3.651.046 ₫ per night from 6 Sept to 7 Sept
3.651.046 ₫
4.271.725 ₫ total
6 Sept - 7 Sept
includes taxes & fees
Stay at this spa hotel in Houston. Enjoy a full-service spa, 2 bars/lounges and a rooftop terrace. Our guests praise the pool and the helpful staff in their ...
Blossom Hotel Houston, Curio Collection by Hilton
La Quinta Inn & Suites by Wyndham Houston Bush IAH South

La Quinta Inn & Suites by Wyndham Houston Bush IAH South

3 out of 5
15510 JFK Blvd Houston TX
The price is 2.083.893 ₫ per night from 4 Sept to 5 Sept
2.083.893 ₫
2.438.154 ₫ total
4 Sept - 5 Sept
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
La Quinta Inn & Suites by Wyndham Houston Bush IAH South
See all 7,407 properties in South Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Main

Find the best South Main areas for the activities you enjoy most.
A cityscape with modern skyscrapers and a park with trees and people.

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.

A large, modern shopping mall with a glass ceiling and multiple levels.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

A cityscape with tall buildings, including a prominent one with 'Texas Children's Hospital' on it, under a partly cloudy sky.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

An art gallery with a minimalist design, featuring a central bench and large abstract paintings on the walls.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or The Chapel of St. Basil while you're exploring the area.

A modern cityscape with a tram and tall buildings.
Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

South Main Travel Guide

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