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Our top choices for San Francisco hotels

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,004 reviews)
"Great Hotel and great staff"
United States
Rudolph
The price is 7.329.888 ₫
8.062.877 ₫ total
includes taxes & fees
7 Feb - 8 Feb
JW Marriott Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,005 reviews)
"Super friendly staff"
United States
Geoffrey
The price is 3.394.342 ₫
3.733.777 ₫ total
includes taxes & fees
23 Jan - 24 Jan
Sheraton Grand Panama

Aloft Panama

Aloft Panama
3.5 star property
San Francisco
8.6 out of 10, Excellent, (916 reviews)
"Great staff..warm and welcoming...enjoyed our stay!"
United States
Alystra Marissa Arjoon
The price is 2.947.718 ₫
3.242.490 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Aloft Panama

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,002 reviews)
"Clean room, friendly staff, very good breakfast and more. "
United States
Patricia
The price is 2.434.101 ₫
2.677.511 ₫ total
includes taxes & fees
31 Jan - 1 Feb
Courtyard by Marriott Panama Multiplaza Mall

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.4 out of 10, Good, (165 reviews)
"Love it!! Very nice!! "
United States
TEYLING
The price is 1.607.374 ₫
5.451.445 ₫ total
includes taxes & fees
19 Jan - 20 Jan
Boutique Apartments Panamá Coco del Mar

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,145 reviews)
"Great staff, breakfast and location "
Canada
Corinne
The price is 2.813.731 ₫
3.095.104 ₫ total
includes taxes & fees
3 Feb - 4 Feb
Ramada Plaza by Wyndham Panama Punta Pacifica

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,002 reviews)
"Great staff, great room, great time in Panama"
United States
Darius
The price is 4.014.624 ₫
4.416.060 ₫ total
includes taxes & fees
9 Feb - 10 Feb
Las Americas Golden Tower Panama

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (558 reviews)
"Excellent room and location"
Canada
Calvin
The price is 4.443.909 ₫
4.888.300 ₫ total
includes taxes & fees
13 Feb - 14 Feb
Residence Inn by Marriott Panama City

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very good, (1,374 reviews)
"Lovely breakfast and very clean and friendly staff!!!"
United States
Ravindra
Megapolis Hotel Panamá

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
7.8 out of 10, Good, (29 reviews)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,149 reviews)
"Definitely a great place to stay. Staff was excellent. "
United States
Eric
The price is 2.947.693 ₫
3.242.462 ₫ total
includes taxes & fees
16 Feb - 17 Feb
Plaza Paitilla Inn Hotel

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,505 reviews)
"Nice comfortable hotel and very friendly staff."
Canada
norah
Decapolis Hotel Panama City

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (2 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is 4.377.441 ₫
8.832.174 ₫ total
includes taxes & fees
19 Jan - 20 Jan
Wanders Panama by Boutique Apartments

Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
8.0 out of 10, Very good, (5 reviews)
"For me was very convenient "
United States
Natalia
The price is 1.540.863 ₫
1.694.949 ₫ total
includes taxes & fees
18 Feb - 19 Feb
Casa Orquídea

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
3.0 star property
San Francisco
2.8 out of 10, (3 reviews)
"Inadequate heating in the pool , poor customer service. No hot water in the shower. It was a terrible experience but it’s a nice place, hopefully with better management can offer outstanding services "
United States
Herbert
The price is 5.024.520 ₫
5.527.103 ₫ total
includes taxes & fees
31 Jan - 1 Feb
Dovle Residences by HMS-Preferred Member

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is 1.750.898 ₫
5.852.720 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Living 73 Panamá by Boutique Apartments

w Engaging 1BR w Balcony in San Francisco

w Engaging 1BR w Balcony in San Francisco
2.0 star property
San Francisco
w Engaging 1BR w Balcony in San Francisco

Lovely 2BR Apt Close to Shops

Lovely 2BR Apt Close to Shops
2.0 star property
San Francisco
The price is 6.593.078 ₫
8.154.041 ₫ total
includes taxes & fees
22 Jan - 23 Jan
Lovely 2BR Apt Close to Shops

Relaxing 2BR Apt at Coco del mar

Relaxing 2BR Apt at Coco del mar
2.0 star property
San Francisco
The price is 6.593.078 ₫
7.252.386 ₫ total
includes taxes & fees
21 Jan - 22 Jan
Relaxing 2BR Apt at Coco del mar

Elegant Loft Pool Gym and Workspaces

Elegant Loft Pool Gym and Workspaces
2.0 star property
San Francisco
The price is 4.846.682 ₫
6.233.005 ₫ total
includes taxes & fees
21 Jan - 22 Jan
Elegant Loft Pool Gym and Workspaces
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Crown Casino.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Felipe

While visiting San Felipe, you might make a stop by sights like Interoceanic Canal Museum and Museum of History Panama.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Top San Francisco Hotel Reviews

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
How many hotels can I expect to find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 259 San Francisco hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.
What is there to do in this Panama City neighbourhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Pacific Center might be the perfect way to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90 and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.

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