The Best Hotels Closest to San Sebastiano in Milan - 2026 Updated Prices

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Our top choices for San Sebastiano hotels

A narrow cobblestone street lined with multi-story buildings, featuring balconies and large windows.

A modern hotel room with a large bed, a desk, and a patterned wall.

A modern kitchen with white cabinets, a red coffee machine, and a dining area with a round table and chairs.

A modern living room with a sofa, a dining table with chairs, a kitchen area with a red appliance, and a flat-screen TV mounted on a wooden panel.

1. Oriana Homèl Milano

Centro Storico, 0.1 km from San Sebastiano

Katrina

5.155.732 ₫

6.221.018 ₫ total

includes taxes & fees

11 Nov - 12 Nov

A modern hotel room with a large bathtub, a bed, a seating area, and a view of the city at night.

A modern living room with leather sofas, a coffee table, and a TV displaying 'AF DUOMO'.

A modern hotel room with a wooden parquet floor, a large bathtub, a dining area with a glass table and chairs, and a living area with sofas and a TV.

A dining table set with various breakfast items including pastries, fruits, and beverages.

2. AF Duomo - Milano Luxury Suites

Centro Storico, 0.3 km from San Sebastiano

Robert

13.662.137 ₫

15.838.455 ₫ total

includes taxes & fees

12 Nov - 13 Nov

A dining area with a table set for four, a lamp, and a framed picture on the wall.

A minimalist bedroom with a large bed, two bedside tables with lamps, a dresser, and two framed abstract artworks on the wall.

A modern kitchen with white cabinetry, a built-in oven, a sink, and a bar area with stools.

A dining area with a table, chairs, a potted plant, and a view of a balcony with a railing.

3. Palazzo Fulcorina Apartments

Centro Storico, 0.4 km from San Sebastiano

Bogdan

4.260.856 ₫

5.236.655 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A building with a sign reading 'CASA LAVENI' and a visible entrance with columns.

An outdoor seating area with two white cushioned chairs, a small round table with a lamp, and a potted plant.

A modern interior with a reception desk, seating area, and a large potted plant.

A modern living room with a sofa, chairs, a coffee table, and a bookshelf.

4. Casa Laveni

Brera, 0.6 km from San Sebastiano

Alexis

10.389.291 ₫

11.833.272 ₫ total

includes taxes & fees

2 Nov - 3 Nov

A balcony with a wooden table, two glasses of orange juice, and a plate of croissants.

A modern living room with a white sofa, a dining table with chairs, a bookshelf, and a flat-screen TV mounted on the wall.

A modern kitchen with a dining area, wooden flooring, and a large wall clock.

A modern bedroom with a large bed, a white bench, and a glass partition wall.

5. Heart Milan Apartments Duomo Missori

Centro Storico, 0.2 km from San Sebastiano

5.954.184 ₫

7.099.315 ₫ total

includes taxes & fees

2 Nov - 3 Nov

A bedroom with a bed, bedside table, and a mirror.

A modern bedroom with a bed, a seating area, and a wardrobe.

A hallway with a geometric ceiling design, potted plants, a glass table, and a view of the outside.

A hotel room with a bed, a wardrobe, a dining table with chairs, and a window with curtains.

6. Casa Brivio

Centro Storico, 0.4 km from San Sebastiano

Chandi

7.301.454 ₫

8.581.312 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A restaurant with a view of a historic building, outdoor seating with tables and chairs, and a modern interior with a sofa and cushions.

A breakfast setup with pastries, coffee, and a vase of flowers in front of a large window with a grid pattern.

A modern bathroom with a freestanding bathtub, a large mirror, and a vanity with a marble countertop.

A classical building facade with a central entrance, large windows, and decorative moldings.

7. Park Hyatt Milano

Centro Storico, 0.4 km from San Sebastiano

Ruth

34.718.733 ₫

38.884.981 ₫ total

includes taxes & fees

2 Nov - 3 Nov

A modern living room with a grey sofa, a dining table, and a TV mounted on the wall.

A modern living room with a sofa, a dining table with chairs, and a TV mounted on the wall.

A hotel room with a bed, pillows, and a view of a tower through a glass door.

A modern hallway with a wooden panel wall, a metal sculpture, and a chair.

8. Heart Milan Apartments - Duomo District

Centro Storico, 0.1 km from San Sebastiano

William

4.561.591 ₫

8.326.175 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A rooftop terrace with two chairs, a table, and a glass of wine. In the background, there is a cityscape with a prominent church and a tall building.

A modern hotel lobby with a red sofa, a table with chairs, a potted plant, and a suitcase.

A modern bedroom with a bed, two green armchairs, a round coffee table, and a painting on the wall.

A modern building with large glass windows, a visible entrance, and a number '48' on the door.

9. Bob W Milan Crocetta

Centro Storico, 0.7 km from San Sebastiano

Maria karolinna

3.690.845 ₫

4.611.333 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A historic building with a prominent entrance, arched windows, and a balcony with balustrades.

A buffet with various fruits, vegetables, and prepared dishes.

A modern outdoor living area with a sofa, chairs, and a table, surrounded by potted plants and a glass door leading to a balcony.

A modern lobby with green and red seating, a patterned carpet, and artwork on the walls.

10. Room Mate Collection Giulia, Milan

Centro Storico, 0.4 km from San Sebastiano

John

11.735.984 ₫

13.488.229 ₫ total

includes taxes & fees

10 Nov - 11 Nov

A spacious indoor dining area with multiple seating arrangements, including booths and tables, and is adorned with large chandeliers and potted plants.

A dining table with a variety of dishes, a glass of wine, and a potted plant.

A modern indoor pool area with a waterfall feature, lounge seating, and contemporary decor.

A modern hotel lobby with a reception desk, potted plants, a pool area, and a chandelier.

11. Palazzo Cordusio Gran Meliá – The Leading Hotels of the World

Centro Storico, 0.4 km from San Sebastiano

Laurel

23.671.926 ₫

26.733.493 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with high ceilings, large columns, and a central seating area.

A restaurant with a modern interior, featuring a central walkway, high ceilings, and a view of the city through large windows.

An outdoor dining area with tables set for two, surrounded by lush greenery and architectural elements.

A spacious lobby with large windows, a central chandelier, and a view of the cityscape.

12. Palazzo Touring Club Milan, A Radisson Collection Hotel

Centro Storico, 0.4 km from San Sebastiano

Jing

11.230.984 ₫

13.048.457 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a large bed, a desk, a chair, a television, and a chandelier.

A modern hotel room with a large bed, a chandelier, and a balcony with a city view.

A modern hotel room with a sofa, a round coffee table with a book and teapot, a TV on a cabinet, and a large mirror with a decorative frame.

A modern hotel room with a dining area, a flat-screen TV, a small table with a vase of flowers, and a bar area with stools.

13. Luxury Suite Milano Duomo

Centro Storico, 0.4 km from San Sebastiano

Ashwani

5.715.107 ₫

6.838.022 ₫ total

includes taxes & fees

9 Nov - 10 Nov

A modern restaurant with glass tables and chairs, large windows, and indoor plants.

A modern interior with a glass desk, a white chair, and a large window.

A modern interior with glass walls, a staircase, and a large illuminated artwork.

A hotel entrance with a glass door, outdoor seating area with planters, and a sign indicating the hotel's name.

14. The Street Milano Duomo | a Design Boutique Hotel

Centro Storico, 0.6 km from San Sebastiano

Jerry

9.915.880 ₫

11.486.114 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A historic building with large windows, ornate balconies, and a prominent entrance.

A modern interior with a central table, orange chairs, a bookshelf, and a kitchen area.

A modern bathroom with a large bathtub, a separate shower area, and a vanity with a mirror.

A narrow doorway leading to a bathroom with a red sink and a mirror above it.

15. Palazzo Segreti

Brera, 0.6 km from San Sebastiano

George

7.522.392 ₫

8.853.277 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A hotel entrance with a sign 'Ostello Bello' and a glass door. There are outdoor seating areas with chairs and tables, surrounded by potted plants and flowers.

A rooftop terrace with potted plants, colorful seating, and a white paper lantern.

A cozy indoor cafe with a variety of seating options, including wicker chairs and tables, and a bar area with a counter and shelves of bottles.

A yellow vintage car with 'Ostello Bello' written on its side parked in a narrow street with outdoor seating and greenery.

16. Ostello Bello Milano Duomo

0.4 km from San Sebastiano

Juanita

4.045.856 ₫

4.624.569 ₫ total

includes taxes & fees

9 Nov - 10 Nov

A table with two drinks and snacks, surrounded by chairs and a green hedge in the background.

A modern hotel lobby with marble flooring, seating areas, a bar, and large windows offering a view of greenery.

A hotel reception area with a marble reception desk, a large window, and a view of the outside.

A modern hotel room with a large bed, a built-in desk, and a large mirror.

17. Hotel Milano Castello

Brera, 0.6 km from San Sebastiano

Junghee

6.864.840 ₫

7.956.376 ₫ total

includes taxes & fees

11 Nov - 12 Nov

A restaurant with checkered flooring, tables set with white tablecloths, and shelves with glassware.

A modern living room with a sofa, armchairs, a coffee table, and a dining area with a table and chairs.

A hotel room with a bed, a sofa, a chair, a small table, and a balcony with a view of buildings.

A hotel room with a bed, a nightstand, a lamp, a window with curtains, and a view of the outside.

18. Speronari Suites

Centro Storico, 0.2 km from San Sebastiano

Christine

8.797.438 ₫

10.226.982 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A rooftop pool area with lounge seating and a city view.

A bar area with stools and a sofa, a bar counter with shelves of bottles, and a seating area with orange furniture.

A modern hotel room with a large window, a sofa, a coffee table, and a side table with books and bottles.

A modern lounge area with seating and tables, a green sofa, and a large portrait on the wall.

19. Casa Brera, a Luxury Collection Hotel, Milan

Scala, 0.7 km from San Sebastiano

Theresa

17.885.408 ₫

20.368.323 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A hallway with a modern design, featuring a sign that reads "THE ROOMS BOUTIQUE HOTEL MILANO".

A modern restaurant with a long counter, yellow chairs, and a seating area with a sofa and tables.

A modern reception area with a marble reception desk, a white chair, and a glass partition.

A modern hotel room with a large bed, bedside lamps, a built-in desk, and a minibar.

20. TheROOMS by TheFLOOR Collection

0.3 km from San Sebastiano

Isal

4.164.946 ₫

5.131.154 ₫ total

includes taxes & fees

1 Nov - 2 Nov

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Top San Sebastiano Hotel Reviews

Hotel Dei Cavalieri Milano Duomo

10/10 Excellent

"Enjoyed our stay. Room was immaculate. Rooftop was great. Staff very accommodating in making reservations and then changing them when we got there late. Breakfast was terrific. I would stay here again."

Room Mate Collection Giulia, Milan

10/10 Excellent

"Amazing location! Within the same building as the Galleria and 50 yards from the Duomo square. Clean modern room and helpful pleasant staff. The only negative is the name. I was put off by the name “ Room Mate” and envisioned back packers.. The hotel is quite the opposite"

Hotel Gran Duca di York True Stay

10/10 Excellent

"Truly enjoyed our stay and would highly recommend!"

Hotel Brunelleschi

8/10 Good

"We enjoyed our stay at this hotel. The hotel was central in Milan to most of the tourist attractions like the Doumo and La Scala. The staff were friendly and accommodating. Looks a little run down, but they make up for it. Recommend this hotel."

The Square Milano Duomo - Preferred Hotels & Resorts

10/10 Excellent

"Great"

Hotel Berna

10/10 Excellent

"The staff was so helpful and friendly! The room was clean and had a comfortable bed. I was upgraded to the main building after booking the annex."

Rosa Grand Milano - Starhotels Collezione

10/10 Excellent

"Top notch absolutely updated hotel and stunning accommodation perfect location"

Ostello Bello Milano Duomo

10/10 Excellent

"."

Hotel Manin

10/10 Excellent

"Thoughtfully designed rooms. Great lighting, bath and shower (rare these days). Lovely garden dining area. Close to good bars and a range of restaurants. Spacious room and bathroom."

Other attractions near San Sebastiano

Biblioteca Ambrosiana

10.0/10 (1 review)

You can learn about the history of Milan with a visit to Biblioteca Ambrosiana. Discover the area's fascinating museums and stunning cathedral.

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Via Torino

During your visit to Milan, you can browse for the perfect souvenirs at Via Torino. Make time to visit the area's stunning cathedral or simply enjoy its charming cafes.

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Chiesa di San Sepolcro

Chiesa di San Sepolcro is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Discover the area's acclaimed art galleries and stunning cathedral.

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Chiesa di Sant'Alessandro in Zebedia

Chiesa di Sant'Alessandro in Zebedia is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Add the area's shops or stunning cathedral to your travel plans.

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Chiesa Santa Maria Presso di San Satiro

9.0/10 (12 reviews)

Chiesa Santa Maria Presso di San Satiro is just one of the places to see in Milan, so why not enjoy the other things to explore during your travels? Add the area's stunning cathedral or shops to your travel plans.

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Museo Mangini Bonomi

You can study the exhibits at Museo Mangini Bonomi, a museum with a storied past, during your holiday in Milan. Experience the area's fascinating museums and acclaimed art galleries.

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Trezzo Live Club

You can make plans for a show at Trezzo Live Club on your trip to Milan. Make time to visit the area's stunning cathedral or simply enjoy its charming cafes.

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Casa Ferrario

You can study the exhibits at Casa Ferrario, a museum with a storied past, during your trip to Milan. Discover the area's acclaimed art galleries and stunning cathedral.

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Frequently asked questions

What's the area like around San Sebastiano?

San Sebastiano is located in a historic area of Milan known for its stunning cathedral and top museums. If you're looking for a convenient place to stay, take a look at the 1327 hotels and other accommodation options you'll find within a mile.

How many hotels will I be able to find close to San Sebastiano?

Expedia has 1327 hotels and other accommodation options within a mile from San Sebastiano.

If I need to cancel the hotel reservation for my stay near San Sebastiano, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the best options available near San Sebastiano.

What can I see and do near San Sebastiano?

Castello Sforzesco, Pinacoteca di Brera and Leonardo da Vinci Museum of Science and Technology feature captivating exhibits. Sights like Cathedral of Milan, Milan Baptistery and Galleria Vittorio Emanuele II are must-sees while exploring the area. You can check out the local talent at Teatro Dal Verme, Teatro alla Scala and Teatro San Babila.

How can I get to San Sebastiano?

With so many choices for transport, seeing the area around San Sebastiano is easy. You can access metro transport at Duomo Station, Via Orefici P.za Cordusio Tram Stop and Cordusio M1 Tram Stop. If you're taking a train into town, Milan Cadorna Nord Station and Milan (XNC-Cadorna Train Station) are the closest stations to Milan Centre.

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for San Sebastiano hotels

1. Oriana Homèl Milano

2. AF Duomo - Milano Luxury Suites

3. Palazzo Fulcorina Apartments

4. Casa Laveni

5. Heart Milan Apartments Duomo Missori

6. Casa Brivio

7. Park Hyatt Milano

8. Heart Milan Apartments - Duomo District

9. Bob W Milan Crocetta

10. Room Mate Collection Giulia, Milan

11. Palazzo Cordusio Gran Meliá – The Leading Hotels of the World

12. Palazzo Touring Club Milan, A Radisson Collection Hotel

13. Luxury Suite Milano Duomo

14. The Street Milano Duomo | a Design Boutique Hotel

15. Palazzo Segreti

16. Ostello Bello Milano Duomo

17. Hotel Milano Castello

18. Speronari Suites

19. Casa Brera, a Luxury Collection Hotel, Milan

20. TheROOMS by TheFLOOR Collection

Top San Sebastiano Hotel Reviews

Hotel Dei Cavalieri Milano Duomo

Room Mate Collection Giulia, Milan

Hotel Gran Duca di York True Stay

Hotel Brunelleschi

The Square Milano Duomo - Preferred Hotels & Resorts

Hotel Berna

Rosa Grand Milano - Starhotels Collezione

Ostello Bello Milano Duomo

Hotel Manin

Other attractions near San Sebastiano

Biblioteca Ambrosiana

Via Torino

Chiesa di San Sepolcro

Chiesa di Sant'Alessandro in Zebedia

Chiesa Santa Maria Presso di San Satiro

Museo Mangini Bonomi

Trezzo Live Club

Casa Ferrario

Frequently asked questions

Explore a world of travel with Expedia