Compare and book 4 Star hotels in Clayton, St. Louis

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Clayton 4 Star Hotels

Tonight
27 Sep - 28 Sep
Tomorrow
28 Sep - 29 Sep
Next weekend
3 Oct - 5 Oct
In two weeks
10 Oct - 12 Oct

Top Clayton 4 Star Hotels

Renaissance St. Louis Airport Hotel
Exterior

Renaissance St. Louis Airport Hotel

4.0 star property
8.4 out of 10, Very good, (1018)
"Beautiful hotel and we loved the music in the dining room."
The price is 3.353.181 ₫
3.922.820 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Renaissance St. Louis Airport Hotel
Hyatt Regency St. Louis at The Arch
Lobby

Hyatt Regency St. Louis at The Arch

4.0 star property
8.4 out of 10, Very good, (4022)
"Close to all events great stay"
The price is 3.300.375 ₫
3.892.100 ₫ total
includes taxes & fees
2 Oct - 3 Oct
Hyatt Regency St. Louis at The Arch
21C Museum Hotel St Louis
Interior

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1390)
"Wonderful stay! "
The price is 3.988.173 ₫
4.795.346 ₫ total
includes taxes & fees
30 Sept - 1 Oct
21C Museum Hotel St Louis
St. Louis Union Station Hotel, Curio Collection by Hilton
Lobby

St. Louis Union Station Hotel, Curio Collection by Hilton

4.0 star property
8.4 out of 10, Very good, (1022)
"Great room and property. "
The price is 4.555.838 ₫
5.418.215 ₫ total
includes taxes & fees
5 Oct - 6 Oct
St. Louis Union Station Hotel, Curio Collection by Hilton
Marriott St. Louis Grand
Exterior

Marriott St. Louis Grand

4.0 star property
8.2 out of 10, Very good, (1043)
"Very convenient to the local sites we wanted to visit."
The price is 4.013.256 ₫
4.772.926 ₫ total
includes taxes & fees
4 Oct - 5 Oct
Marriott St. Louis Grand
DoubleTree by Hilton St. Louis Airport
Bar (on property)

DoubleTree by Hilton St. Louis Airport

4.0 star property
7.8 out of 10, Good, (820)
"Very clean and nice staff "
The price is 3.007.302 ₫
3.528.709 ₫ total
includes taxes & fees
5 Oct - 6 Oct
DoubleTree by Hilton St. Louis Airport
River City Casino & Hotel
Daily cooked-to-order breakfast for a fee

River City Casino & Hotel

4.0 star property
9.0 out of 10, Wonderful, (1394)
"The hotel was very clean, hospitality was awesome and the ease of check in and check out was perfect. We will be back for sure!!!"
The price is 2.323.200 ₫
3.087.567 ₫ total
includes taxes & fees
19 Oct - 20 Oct
River City Casino & Hotel
Live by Loews - St.Louis
Breakfast, lunch and dinner served

Live by Loews - St.Louis

4.0 star property
9.2 out of 10, Wonderful, (1060)
"Great quick stay!"
The price is 4.462.107 ₫
5.306.739 ₫ total
includes taxes & fees
5 Oct - 6 Oct
Live by Loews - St.Louis
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Bar (on property)

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4.0 star property
8.8 out of 10, Excellent, (1047)
"Very comfortable bed, convenient location, friendly people. "
The price is 2.798.718 ₫
3.328.488 ₫ total
includes taxes & fees
12 Oct - 13 Oct
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
DoubleTree by Hilton St. Louis Forest Park
In-room safe, desk, blackout curtains, iron/ironing board

DoubleTree by Hilton St. Louis Forest Park

4.0 star property
8.2 out of 10, Very good, (1009)
"Enjoyed our visit"
The price is 3.456.153 ₫
4.075.807 ₫ total
includes taxes & fees
12 Oct - 13 Oct
DoubleTree by Hilton St. Louis Forest Park
Hilton St. Louis Frontenac
Lobby

Hilton St. Louis Frontenac

4.0 star property
8.8 out of 10, Excellent, (1008)
"Great stay. "
The price is 3.792.791 ₫
4.418.147 ₫ total
includes taxes & fees
19 Oct - 20 Oct
Hilton St. Louis Frontenac
Ameristar Casino Resort and Spa
Casino

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very good, (1025)
"Beautiful hotel with friendly staff!"
The price is 4.690.493 ₫
5.920.081 ₫ total
includes taxes & fees
5 Oct - 6 Oct
Ameristar Casino Resort and Spa
Moonrise Hotel
Exterior

Moonrise Hotel

4.0 star property
9.0 out of 10, Wonderful, (1905)
"Food on the rooftop was amazing "
The price is 3.764.012 ₫
4.476.893 ₫ total
includes taxes & fees
6 Oct - 7 Oct
Moonrise Hotel
The Westin St. Louis
Lounge

The Westin St. Louis

4.5 star property
8.6 out of 10, Excellent, (1011)
"Very clean and friendly staff. "
The price is 3.568.365 ₫
4.172.455 ₫ total
includes taxes & fees
12 Oct - 13 Oct
The Westin St. Louis
The Royal Sonesta Chase Park Plaza St. Louis
Seasonal outdoor pool

The Royal Sonesta Chase Park Plaza St. Louis

4.5 star property
9.0 out of 10, Wonderful, (1013)
"Great and family friendly!! Would stay again!"
The price is 5.489.184 ₫
7.251.700 ₫ total
includes taxes & fees
12 Oct - 13 Oct
The Royal Sonesta Chase Park Plaza St. Louis
Marriott St. Louis Airport
Lobby

Marriott St. Louis Airport

4.0 star property
8.0 out of 10, Very good, (1013)
"Very pleasant staff."
The price is 3.369.023 ₫
4.020.525 ₫ total
includes taxes & fees
4 Oct - 5 Oct
Marriott St. Louis Airport
Hilton St. Louis at the Ballpark
3 bars/lounges, rooftop bar

Hilton St. Louis at the Ballpark

4.0 star property
7.6 out of 10, Good, (1029)
"I enjoyed this stay."
The price is 3.613.251 ₫
4.297.203 ₫ total
includes taxes & fees
23 Oct - 24 Oct
Hilton St. Louis at the Ballpark
Hilton Pennywell St. Louis at the Arch
Exterior

Hilton Pennywell St. Louis at the Arch

4.0 star property
8.8 out of 10, Excellent, (949)
"Fantastic property to stay at! "
The price is 3.358.462 ₫
3.960.601 ₫ total
includes taxes & fees
13 Oct - 14 Oct
Hilton Pennywell St. Louis at the Arch
The Cheshire
Terrace/patio

The Cheshire

4.0 star property
8.6 out of 10, Excellent, (1013)
"Great staff, wonderful property."
The price is 3.564.410 ₫
4.232.309 ₫ total
includes taxes & fees
12 Oct - 13 Oct
The Cheshire
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Terrace/patio

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4.0 star property
8.8 out of 10, Excellent, (1018)
"I had a great experience this weekend and I would absolutely recommend this property."
The price is 3.358.462 ₫
3.960.600 ₫ total
includes taxes & fees
5 Oct - 6 Oct
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Clayton.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street, St. Louis, MO
The price is 11.221.275 ₫ per night from 4 Oct to 5 Oct
11.221.275 ₫
13.120.924 ₫ total
4 Oct - 5 Oct
includes taxes & fees
9.4/10 Exceptional! (1,002 reviews)
Still don't see what you're looking for?
See all properties in Clayton.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Clayton Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Clayton?
Le Méridien St. Louis Clayton is a 4-star hotel in Clayton that ranks highly among Expedia guests. A swimming pool and a terrace are just a couple of its amenities. Travellers also recommend The Cheshire. From designer toiletries to a pillowtop mattress, it offers conveniences that cater to every aspect of your enjoyment and relaxation.
How much does it cost to stay in a 4-star hotel in Clayton?
With Expedia's search and sort filters, locking in a superb deal on a 4-star hotel in Clayton just got easier. Start by entering your chosen travel dates and length of your stay. Then sort the results by price and pick the option that best fits your style and budget.

  • Search for the lowest price from 13.120.924 ₫

What's the difference between 5-star and 4-star hotels in Clayton?
If you choose to holiday at a 4-star hotel in Clayton, you'll usually find loads of conveniences to ensure you're comfortable, such as a restaurant, pool and gym. You can look forward to high-quality service and upscale surroundings. Go for a 5-star hotel and you'll get a few extra bells and whistles — think on-site spas, 24-hour front desk and opulent turndown services. You're likely to get extra amenities and premium services at a 5-star retreat, but both are awesome options for luxury guests.

Explore a world of travel with Expedia

Explore a world of travel with Expedia