A historic stone fortress with a central dome and surrounding walls.

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Check availability on Colon 4 Star Hotels

Tonight
3 Oct - 4 Oct
Tomorrow
4 Oct - 5 Oct
Next weekend
9 Oct - 11 Oct
In two weeks
16 Oct - 18 Oct

Our top choices for Colon 4-star hotels

A multi-story building with balconies, arched windows, and decorative railings.
A building with a balcony and a street view.
A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.
A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

1. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
United States
Olga
4.939.971 ₫
5.433.968 ₫ total
includes taxes & fees
5 Oct - 6 Oct
Central Hotel Panama Casco Viejo
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A rooftop lounge with modern seating and a panoramic city view.
A rooftop pool area with purple lounge chairs and a city skyline in the background.
A modern spa area with a hot tub, seating, and a city view.

2. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
Sheena
4.174.084 ₫
4.591.492 ₫ total
includes taxes & fees
26 Oct - 27 Oct
Megapolis Hotel Panamá
Pool
A buffet area with a variety of dishes, a long counter with food, and a seating area with tables and chairs.
A hotel room with a large bed, a smaller bed, a sofa, a TV mounted on the wall, and a dining area with a table and chairs.
A reception area with marble reception desks and a sign indicating the reception desk.

3. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Bella Vista
United States
abbigale
2.805.297 ₫
3.085.827 ₫ total
includes taxes & fees
29 Oct - 30 Oct
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
A balcony with wicker chairs and a view of the cityscape.
A reception area with a marble wall, a 'Free Wireless Internet' sign, and a floral arrangement.
A hotel room with a large bed, a desk with a lamp, a chair, and a view of a cityscape through a window.
A multi-story hotel with a modern facade, large windows, and a prominent entrance with a covered area.

4. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco
United States
Maria
2.716.941 ₫
2.988.635 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Ramada Plaza by Wyndham Panama Punta Pacifica
A resort with a large swimming pool, thatched-roof structures, and palm trees.
A hotel room with a large bed, a chair, a desk, and a view of the ocean.
A well-maintained garden with a pathway leading to a gazebo, surrounded by palm trees and a view of the sea.
An outdoor dining area with tables and chairs, overlooking a body of water and a forested island.

5. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
United States
Tony
7.228.564 ₫
7.228.564 ₫ total
includes taxes & fees
13 Oct - 14 Oct
Dreams Playa Bonita Panama - All Inclusive
A modern building with a glass facade, a curved structure, and a flat roof.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A rooftop lounge area with clear glass tables and chairs, a pool, and potted plants.
A modern hotel room with a large bed, a desk with a flat-screen TV, a city view, and a large painting on the wall.

6. Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
United States
Jorge Luis
2.465.756 ₫
2.712.332 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Decapolis Hotel Panama City
A buffet with various food items including fruits, juices, and cheeses.
A gym with treadmills, weight machines, and dumbbells.
An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.
A hotel reception area with a wooden reception desk, seating area with chairs and ottomans, and a large window providing natural light.

7. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
United States
Chaloma
2.629.884 ₫
2.892.872 ₫ total
includes taxes & fees
23 Oct - 24 Oct
Courtyard by Marriott Panama Metromall
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
A modern reception area with a wooden panel wall, a sign indicating 'Marriott Bonvoy', and three reception desks with digital displays.
A modern cafe with wooden tables and chairs, large windows, and decorative vases on shelves.
A modern lounge area with a wooden partition, a bar with a variety of bottles, and a seating area with chairs.

8. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
San Francisco
United States
SHARROW
2.950.044 ₫
3.245.048 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Courtyard by Marriott Panama Multiplaza Mall
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
An indoor swimming pool with lounge chairs and a modern interior design.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.
A spacious lobby with a staircase, seating area, and a bar.

9. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
United States
Armando
3.945.858 ₫
4.340.444 ₫ total
includes taxes & fees
11 Oct - 12 Oct
Las Americas Golden Tower Panama
A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.
A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.
A spacious lobby with high ceilings, large windows, and modern lighting fixtures.
A buffet setup with various dishes and utensils.

10. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
United States
Richard
4.389.606 ₫
4.828.566 ₫ total
includes taxes & fees
10 Oct - 11 Oct
Marriott Panama Hotel
A hotel room with a sofa, a coffee table, a TV, and a cabinet.
A rooftop swimming pool with lounge chairs and a city skyline in the background.
A cityscape with modern high-rise buildings, including a prominent tower labeled 'TOWERBANK.'
A hotel room with a bed, bedside tables, a nightstand, a lamp, a digital clock, a bathroom with a toilet, a sink, and a mirror.

11. Studio Coliving

Studio Coliving
Bella Vista
United States
Phillip
Studio Coliving
A rooftop pool with sun loungers and a city skyline in the background.
A bar area with a curved counter, multiple screens, and a patterned carpet.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.
A long, narrow hallway with a wooden floor and light-colored walls.

12. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
United States
kevin
2.318.179 ₫
3.978.567 ₫ total
includes taxes & fees
10 Oct - 11 Oct
Waymore Hotel Spa & Casino
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.
A buffet setup with various food items, including bread, pastries, and a variety of dishes in bowls.
A hotel room with a bed and a view of a cityscape through sheer curtains.
A bar area with a variety of liquor bottles, a counter, and seating with tables and chairs.

13. Novotel Panama City

Novotel Panama City
Bella Vista
United States
Angel
2.923.537 ₫
3.215.891 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Novotel Panama City
A resort with a pool area, lounge chairs, and a view of a bridge at night.
A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.
A formal dining area with round tables, white tablecloths, and blue lace borders.
A hotel room with a bed, a TV on a wooden cabinet, a nightstand with a lamp, and a view of the outdoors through a glass door.

14. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
Amador
United States
Jose
2.034.984 ₫
2.238.345 ₫ total
includes taxes & fees
17 Oct - 18 Oct
Radisson Hotel Panama Canal
A buffet with various food items and a decorative plant.
A spacious lobby with a high ceiling, a glass railing on the upper level, and a seating area with modern furniture.
A gym with treadmills, weight machines, and a red carpet.
A spa area with a hot tub, candles, and a curved bench.

15. Sheraton Grand Panama

Sheraton Grand Panama
San Francisco
United States
Noel
4.792.203 ₫
5.271.423 ₫ total
includes taxes & fees
12 Oct - 13 Oct
Sheraton Grand Panama
A poolside area with covered seating and palm trees.
A modern hotel lobby with a glass facade, seating area with loungers, and a wooden floor.
A modern living room with a city view, a flat-screen TV, and a dining area with white chairs and a table.
A modern reception area with a large window, a geometric patterned floor, and two potted plants.

16. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Bella Vista
United States
Jahzenia
6.730.633 ₫
7.403.696 ₫ total
includes taxes & fees
4 Oct - 5 Oct
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
A spacious indoor area with high ceilings, large windows, and multiple dining tables.
A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.
A white building with multiple balconies, large windows, and decorative railings.
A multi-story hotel with a central courtyard, balconies, and a view of the city skyline.

17. American Trade Hotel

American Trade Hotel
Casco Viejo
United States
Ashleigh-Ann
5.276.618 ₫
5.804.280 ₫ total
includes taxes & fees
13 Oct - 14 Oct
American Trade Hotel
A wooden door with a number plate, a black and white striped bag, and a lantern on the ground.
A rooftop terrace with a city skyline view, a pool, and outdoor seating.
A rooftop bar with potted plants, seating, and a view of a city skyline.
A restaurant with a wine display and a table set for two.

18. Hotel Casa Panamá

Hotel Casa Panamá
Casco Viejo
United States
Naveera Jyoti
1.671.304 ₫
1.838.434 ₫ total
includes taxes & fees
26 Oct - 27 Oct
Hotel Casa Panamá
A high-rise hotel with multiple floors, a prominent "Residence Inn by Marriott" sign, and a "Panama Clinic" sign.
A modern bar area with multiple seating options and a view of the cityscape.
A hotel room with two beds, a sofa, a bench, a TV, and a view of buildings.
A modern conference room with a long table, colorful chairs, and large windows offering a city view.

19. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
San Francisco
United States
Desmon
4.885.556 ₫
5.374.112 ₫ total
includes taxes & fees
27 Oct - 28 Oct
Residence Inn by Marriott Panama City
A rooftop pool with lounge chairs and a city skyline view.
A woman sitting on a bed in a hotel room with a city view.
A gym with treadmills, elliptical machines, free weights, and a bench.
A person seated on a wicker chair with a view of a cityscape through large windows.

20. Hotel Dann Carlton Marinn Place Panama Financial District

Hotel Dann Carlton Marinn Place Panama Financial District
Bella Vista
United States
Eliana
1.904.414 ₫
2.809.498 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Hotel Dann Carlton Marinn Place Panama Financial District
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Colon.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
3.576.889 ₫
3.934.578 ₫ total
25 Oct - 26 Oct
includes taxes & fees
9/10 Wonderful! (5,998 reviews)
Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

47th St. & Uruguay Street Panama City Panama
6.584.586 ₫
7.243.045 ₫ total
31 Oct - 1 Nov
includes taxes & fees
9/10 Wonderful! (1,001 reviews)
Waldorf Astoria Panama
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Calle Primera Oeste, San Felipe Panama City Panama
9.121.437 ₫
10.033.581 ₫ total
3 Nov - 4 Nov
includes taxes & fees
Sofitel Legend Casco Viejo, Panama City
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Colon

Explore the colourful Zona Libre free trade zone for duty-free shopping and visit the historic Colon 2000 cruise port. Discover Panama's colonial history at Fort San Lorenzo, located on the Caribbean coast outside the city.

See all hotels in Colon
A coastal archaeological site with ruins and a clear view of the ocean with boats.

Top Colon Hotel Reviews

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

10/10 Excellent
"Un servicio excelente y muy limpio el hotel. El desayuno muy regular, no muy buena calidad la comida, no varían."
patricia 8-night trip
Posted 13 hours ago
Waymore Hotel Spa & Casino
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

10/10 Excellent
"Todo bien"
Jorge 1-night trip
Posted 14 hours ago
Ramada Plaza by Wyndham Panama Punta Pacifica
Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"Excellent hotel with a convenient price with the breakfast included."
Armando Bey 1-night trip
Posted 21 hours ago
Decapolis Hotel Panama City
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

10/10 Excellent
"This is a great hotel, and the location was perfect. The rooms were nice, and the staff were very friendly. I would highly recommend it."
Thomas 5-night trip
Posted 2 days ago
Central Hotel Panama Casco Viejo
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

8/10 Good
"Muy bien ubicado.................."
ariel 1-night trip
Posted 6 days ago
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Frequently asked questions

What are the best 4-star hotels in Colon?
If you're looking for upscale comfort and loads of amenities on your Colon getaway, check out Radisson Colon 2,000 Hotel & Casino. This popular 4-star hotel offers proposal/romance packages and premium bedding. Melia Panama Canal also gets top reviews from Expedia customers. A terrace and a swimming pool are among its conveniences.
How much does it cost to stay in a 4-star hotel in Colon?
To lock in a 4-star hotel in Colon that's within your budget, take advantage of Expedia's filter tool. Take a look at what's available during your preferred dates and use our pricing filter to set your maximum rate. You can also list your results by the cheapest escape first.
  • Search for the lowest price from 3.934.578 ₫
What's the difference between 5-star and 4-star hotels in Colon?
Offering a welcoming traveller experience and upscale décor, 4-star hotels are a fantastic option for your Colon holiday. These types of stays generally feature lots of handy amenities that make it simple to unpack and recharge — think pillowtop mattresses, gyms and restaurants. Or live in the lap of luxury at a 5-star hotel designed to spoil you with luxury perks and amenities. On-site health clubs, complimentary toiletries and gourmet dining are typically featured at these swanky retreats.