Compare and book 4 Star hotels in West Main Historic District, Louisville

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on West Main Historic District 4 Star Hotels

Tonight
4 Dec - 5 Dec
Tomorrow
5 Dec - 6 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top West Main Historic District 4 Star Hotels

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3814)
"10/10 best hotel in Louisville "
United States
James
The price is 2.861.470 ₫
3.366.804 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Galt House Hotel Trademark Collection by Wyndham
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1698)
"Wonderful property and staff. Would love to stay again. "
United States
Hanna
The price is 4.409.777 ₫
5.188.543 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Omni Louisville Hotel
Dinner served
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1102)
"Clean, hotel was amazing, great breakfast "
United States
Alana
The price is 3.143.662 ₫
3.698.832 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Embassy Suites Louisville Downtown
Premium bedding, in-room safe, desk, laptop workspace
Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

4.0 star property
Louisville
9.4 out of 10, Exceptional, (1664)
"Clean rooms and front desk staff very pleasant."
United States
Kim
Derby City Gaming & Hotel - A Churchill Downs Property
Lobby
The Brown Hotel

The Brown Hotel

4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1149)
"I loved everything about this place"
United States
Steven
The price is 3.119.926 ₫
3.670.858 ₫ total
includes taxes & fees
18 Dec - 19 Dec
The Brown Hotel
Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1012)
"Nice hotel and rooms. "
United States
James
The price is 3.564.311 ₫
4.193.768 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Hotel Genevieve part of JdV by Hyatt
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1000)
" Loved our stay, would definitely plan to come back if we are ever in the area again."
United States
Erica
The price is 3.665.847 ₫
4.445.101 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
21c Museum Hotel Louisville
Breakfast, lunch and dinner served
Hyatt Regency Louisville

Hyatt Regency Louisville

4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1002)
"Enjoyed our stay "
United States
Jedediah
The price is 3.059.268 ₫
3.599.536 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Hyatt Regency Louisville
Exterior
Marriott Louisville East

Marriott Louisville East

4.0 star property
Jeffersontown
9.0 out of 10, Wonderful, (1001)
"Very nice hotel, rooms were clean and comfortable, breakfast is great!"
United States
Miguel
The price is 2.891.799 ₫
3.402.491 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Marriott Louisville East
Deluxe Single Room, 1 King Bed, River View | View from room
The Grady

The Grady

4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1020)
"The location was outstanding and atmosphere was very nice."
United States
Malcolm
The price is 3.673.759 ₫
4.322.535 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The Grady
Restaurant
Louisville Marriott Downtown

Louisville Marriott Downtown

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1000)
"Room was great, but the service by the attendant that wait on me was exceptional in what she done for me."
United States
Michael
The price is 4.513.475 ₫
5.310.556 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Louisville Marriott Downtown
Exterior
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (427)
"Great location. Great restraunt, great staff. Pleasurable experience!"
United States
Harrison
The price is 4.461.331 ₫
5.249.201 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel Distil, Autograph Collection
Exterior
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (52)
"Lovely hotel in downtown Louisville. Well appointed room, comfy bed and outstanding dining. "
United States
Michelle
The price is 3.788.481 ₫
4.457.527 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Lobby
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1001)
"Room looked very nice when we checked in"
United States
Todd
The price is 3.026.531 ₫
3.561.016 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Seelbach Hilton Louisville Downtown
Signature Suite, 1 Queen Bed, Non Smoking | Premium bedding, down duvets, memory-foam beds, individually furnished
Stellar Suites

Stellar Suites

4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (117)
"Clean and great location "
United States
Greg
The price is 3.111.750 ₫
4.989.310 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Stellar Suites
Deluxe Room, 1 King Bed (Culbertson Suite) | Balcony
The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B

4.0 star property
New Albany
9.8 out of 10, Exceptional, (646)
"Have stayed here once before. Accommodations are wonderful and the sit down breakfast is lovely. Highly recommend this beautiful property."
United States
Kathy
The price is 2.397.569 ₫
2.709.034 ₫ total
includes taxes & fees
7 Dec - 8 Dec
The Pepin Mansion Historic B&B
Seasonal outdoor pool
CozySuites at Nulu

CozySuites at Nulu

4.0 star property
Downtown Louisville
8.2 out of 10, Very good, (26)
"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "
United States
William
The price is 1.661.499 ₫
5.295.962 ₫ total
includes taxes & fees
8 Dec - 9 Dec
CozySuites at Nulu
BBQ/picnic Area
stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville

4.0 star property
Clarksville
9.8 out of 10, Exceptional, (43)
"Excellent stay. One of my favorite hotels in the area. They never disappoint "
United States
Julia
stayAPT Suites Louisville North-Clarksville
32-inch Smart TV with cable channels
The Reserve on Main

The Reserve on Main

4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is 3.204.319 ₫
5.037.903 ₫ total
includes taxes & fees
8 Dec - 9 Dec
The Reserve on Main
Interior
Inn at St James Court

Inn at St James Court

4.0 star property
Old Louisville
9.8 out of 10, Exceptional, (131)
"Lovely Victorian house in a gorgeous and convenient gorgeous neighborhood. "
United States
marcia
Inn at St James Court
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in West Main Historic District.
Louisville Bourbon Inn

Louisville Bourbon Inn

1332 S 4th St Louisville KY
The price is 6.988.845 ₫ per night from 8 Dec to 9 Dec
6.988.845 ₫
8.111.952 ₫ total
8 Dec - 9 Dec
includes taxes & fees
10/10 Exceptional! (19 reviews)
Still don't see what you're looking for?
See all properties in West Main Historic District.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top West Main Historic District Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in West Main Historic District?
Kick back in the comfort and quality of 21c Museum Hotel Louisville. This 4-star hotel around West Main Historic District is ranked highly by many Expedia guests and comes with massage services and spa facilities. Another in-demand choice in or near this neighbourhood is Galt House Hotel Trademark Collection by Wyndham. Concierge services and massage services are two amenities that help make it popular.
How much does it cost to stay in a 4-star hotel in West Main Historic District?
With Expedia's search and sort filters, locking in a superb deal on a 4-star hotel in West Main Historic District just got simpler. Start by keying in your chosen arrival date and length of your stay. Then sort the results by price and pick a hotel that best fits your style and budget.

  • Search for the lowest price from 8.111.952 ₫

What's the difference between 5-star and 4-star hotels in West Main Historic District?
Give yourself the luxury treatment during your West Main Historic District escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are usually packed with amenities, including large beds, bathrobes and more. A 5-star hotel will go above and beyond to make your trip an even more indulgent and memorable one. Concierge assistance, luxurious spas and world-class dining are a few of the first-rate conveniences and services you'll likely have access to.

Explore a world of travel with Expedia