Search Spa Hotels in West Main Historic District

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Check availability on West Main Historic District Spa Hotels

Tonight
4 Dec - 5 Dec
Tomorrow
5 Dec - 6 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top West Main Historic District Spa Hotels

Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1000)
" Loved our stay, would definitely plan to come back if we are ever in the area again."
United States
Erica
The price is 3.665.847 ₫
4.445.101 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
21c Museum Hotel Louisville
32-inch Smart TV with cable channels
The Reserve on Main

The Reserve on Main

4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is 3.204.319 ₫
5.037.903 ₫ total
includes taxes & fees
8 Dec - 9 Dec
The Reserve on Main
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1698)
"Wonderful property and staff. Would love to stay again. "
United States
Hanna
The price is 4.409.777 ₫
5.188.543 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Omni Louisville Hotel
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3814)
"10/10 best hotel in Louisville "
United States
James
The price is 2.861.470 ₫
3.366.804 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Galt House Hotel Trademark Collection by Wyndham
Exterior detail
Central Park Bed & Breakfast

Central Park Bed & Breakfast

4.0 star property
Old Louisville
9.4 out of 10, Exceptional, (56)
"The room was beautiful, breakfast was delicious and the park across the street was lovely. I especially enjoyed having coffee on the back veranda."
United States
Cher
The price is 3.575.651 ₫
4.150.319 ₫ total
includes taxes & fees
5 Dec - 6 Dec
Central Park Bed & Breakfast
Indoor pool
Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination

3.5 star property
Elizabeth
8.2 out of 10, Very good, (1025)
"Easy parking, Very friendly/helpful staff, easy check in/out, Nice casino, Good food options"
United States
Leslie
The price is 1.877.757 ₫
2.611.771 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Caesars Southern Indiana - A Caesars Rewards Destination
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top West Main Historic District Hotel Reviews

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Frequently asked questions

Looking to holiday at a spa hotel in West Main Historic District?
Forget the stress of everyday life and book yourself a lush spa hotel. Travellers highly recommend the restaurants and bars in West Main Historic District. Enjoy the live music and riverfront during your holiday. Spa hotels are a great way to break out of your daily routine and add a layer of luxury to your weekend away.
How many spa hotels are there in West Main Historic District?
Among Expedia's 237 accommodation options in West Main Historic District, there are 3 spa hotels.
What's there to see and do in West Main Historic District?
Experience all that West Main Historic District has to offer when you visit Frazier International History Museum, Louisville Slugger Museum and Louisville Science Center. If you have a bit of extra time while you're in the area, you might want to check out 21c Museum Hotel and Muhammad Ali Center.
What is a West Main Historic District spa hotel?
Spa hotels in West Main Historic District feature full on-site spas which offer services such as couples massages and a choice of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on holiday.