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June 2026

July 2026

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Where to stay in Mark Twain

Find the best Mark Twain areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

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Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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Central West End

If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.

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Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

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Top Mark Twain Hotel Reviews

River City Casino & Hotel

10/10 Excellent

"A clean, comfortable, quiet room at a reasonable price. I really liked the walking path along the Mississippi River across the street from the hotel."

Hollywood Casino & Hotel St. Louis

8/10 Good

"Overall room was nice. A few things I noticed to make me give it 4 stars. - the coffee maker was gross covered with dust and grime - I understand being charged a deposit for the room, but being charged for parking and wifi when I’m already paying a lot of money for a room is ridiculous, also I did not see anything when booking the room about needing to pay for parking and WiFi upon checking in - they require you to bring your own water bottle to refill with water at their water stations, which I do not remember seeing anything about this either until already checked in"

Live by Loews - St.Louis

2/10 Terrible

"I honestly didn’t like anything about it compared to other hotels at the same stars. The room that we paid for supposed two queen size I but they are more like full or double sizes. (4.6-4.9 ft wide to be exact). The sheets had spots on them, same the furniture. I had to call the supervisor to clean some blood spots or something red/brown from the nightstand. the phone had like green toothpaste on it. I have pictures of all of these. I asked to change the room , they refused and sent someone to do a little wiping. like seriously it was the worst experience we had… there were spots on the carpet; just awful! Waste of money and luckily, we stayed only one night… awful view as well. We Supposed to have a courtyard view but we faced a full wall in front of us. Parking valet was $50 or $40 to park yourself. When we stayed at the Four seasons, a night before, the parking was included. The room was nice and clean. Everything was great and for $60 more as you don’t have to pay the parking,it was more it was worth it. Won’t stay at this Live by Lowe again."

Hilton St. Louis at the Ballpark

6/10 Okay

"Check-in was not available at 4pm. No comp was offered. Never received the promised call when our room was ready. I had to get back in line and inquire again. My 8 year old was told by staff the pool was closed for weather; it was not. Thankfully we went and checked the area out and discovered it was fully open with other swimmers."

Clayton Plaza Hotel & Extended Stay

4/10 Poor

"An event was occurring in the ballroom right above our room. It was after 9 pm and the room was bouncing and creaking with the dancing and hopping up and down, enough to feel like motion sickness. We requested to be moved and the staff person said they were fully booked, and was rude about the situation. I checked the website and discovered the staff lied and several rooms were available that night. We were moved to another room where the toilet was broken and the shower head didn’t work. "

Frequently asked questions

What's it like in Mark Twain?

Travellers will be sure to find plenty to entertain them in St. Louis's Mark Twain neighbourhood.

If I need to cancel my hotel reservation in Mark Twain, will I receive a refund?

Yes, the majority of hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to review the best deals available in Mark Twain.

What is there to do around this St. Louis neighbourhood?

Bellefontaine Cemetery, Calvary Cemetery and Julia Davis Branch Library are just a few of the places to visit in and around Mark Twain. Shelley House and The Ville Monument are also worth a visit when you're out sightseeing in St. Louis.

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Our top choices for Mark Twain hotels

Hyatt Select St. Louis Airport

Holiday Inn Express Troy by IHG

Drury Plaza Hotel St. Louis at the Arch

Pear Tree Inn St. Louis Airport

Super 8 by Wyndham Troy IL/St. Louis Area

The Principal Hotel

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Wingate by Wyndham St. Louis Airport

Comfort Inn Edwardsville - St. Louis

Drury Inn & Suites St. Louis Airport

River City Casino & Hotel

Drury Inn & Suites St. Louis O'Fallon, IL

Hampton Inn St. Charles St. Peters

Pear Tree Inn St. Louis Near Union Station

Super 8 by Wyndham St Charles

Holiday Inn Express & Suites Edwardsville by IHG

Hilton St. Louis Airport

Wingate by Wyndham St. Louis/Fenton Route 66

Best Western St. Louis Inn

Drury Inn & Suites St. Louis Collinsville

Where to stay in Mark Twain

Downtown St. Louis

Clayton

Creve Coeur

Central West End

Downtown West

Top Mark Twain Hotel Reviews

River City Casino & Hotel

Frequently asked questions

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