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Top Trending Hotels Near Otay Mesa, San Diego

Quality Suites San Diego Otay Mesa
Desk, laptop workspace, blackout curtains, iron/ironing board

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1001)
"Clean, friendly staff and yummy breakfast :)"
The price is 2.613.204 ₫
2.972.520 ₫ total
includes taxes & fees
5 Oct - 6 Oct
Quality Suites San Diego Otay Mesa
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Exterior

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
8.0 out of 10, Very good, (1467)
"Very good to stayed "
The price is 3.009.144 ₫
3.422.901 ₫ total
includes taxes & fees
9 Oct - 10 Oct
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Palihotel San Diego Gaslamp Quarter
Rooftop terrace

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.8 out of 10, Excellent, (1871)
"would definitely stay again!"
The price is 3.062.254 ₫
3.550.474 ₫ total
includes taxes & fees
23 Oct - 24 Oct
Palihotel San Diego Gaslamp Quarter
The Horton Grand, Downtown/Gaslamp Quarter
Serves dinner and happy hour

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2584)
"Great location and lovely staff. "
The Horton Grand, Downtown/Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Exterior

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
9.0 out of 10, Wonderful, (1143)
"Great stay! "
The price is 4.461.500 ₫
5.172.886 ₫ total
includes taxes & fees
12 Oct - 13 Oct
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Wyndham San Diego Bayside
Terrace/patio

Wyndham San Diego Bayside

4.0 star property
8.4 out of 10, Very good, (5958)
"Great stay near the airport."
The price is 4.013.108 ₫
5.417.902 ₫ total
includes taxes & fees
29 Oct - 30 Oct
Wyndham San Diego Bayside
Gaslamp Plaza Suites
Lobby

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1007)
"Had a great stay "
The price is 2.848.608 ₫
3.240.292 ₫ total
includes taxes & fees
6 Oct - 7 Oct
Gaslamp Plaza Suites
Hard Rock Hotel San Diego
Outdoor pool

Hard Rock Hotel San Diego

4.0 star property
9.0 out of 10, Wonderful, (2974)
"Loved staying here. Will definitely stay again "
The price is 4.728.689 ₫
6.694.667 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Hard Rock Hotel San Diego
Ramada Suites by Wyndham San Diego/Hotel Circle Area
Outdoor pool

Ramada Suites by Wyndham San Diego/Hotel Circle Area

2.5 star property
6.2 out of 10, (1009)
"comfortable, easy access, friendly staff"
The price is 1.761.933 ₫
2.025.365 ₫ total
includes taxes & fees
6 Oct - 7 Oct
Ramada Suites by Wyndham San Diego/Hotel Circle Area
Best Western Plus Marina Gateway Hotel
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3299)
"Great hotel"
The price is 3.402.504 ₫
3.749.348 ₫ total
includes taxes & fees
5 Oct - 6 Oct
Best Western Plus Marina Gateway Hotel
El Cordova Hotel on Coronado Island
Lobby

El Cordova Hotel on Coronado Island

3.5 star property
8.8 out of 10, Excellent, (1003)
"We love this hotel. It gives a feel of having your own apartment on the island. The rooms is are clean and comfortable. The staff is welcoming and accommodating. The location is perfect. Close walking distance to the beach, dining, shopping, as well as the famous Del across the street. "
El Cordova Hotel on Coronado Island
The Sofia Hotel
Front of property

The Sofia Hotel

3.5 star property
8.4 out of 10, Very good, (1591)
"Close to a lot of areas, would stay here again."
The Sofia Hotel
Staypineapple, Hotel Z, Gaslamp San Diego
Premium bedding, pillow-top beds, desk, blackout curtains

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
9.4 out of 10, Exceptional, (1001)
"Great staff and clean rooms"
The price is 3.925.613 ₫
5.314.396 ₫ total
includes taxes & fees
22 Oct - 23 Oct
Staypineapple, Hotel Z, Gaslamp San Diego
Super 8 by Wyndham El Cajon/San Diego
Lobby

Super 8 by Wyndham El Cajon/San Diego

2.0 star property
7.8 out of 10, Good, (1001)
"Great place "
The price is 1.840.065 ₫
2.027.660 ₫ total
includes taxes & fees
19 Oct - 20 Oct
Super 8 by Wyndham El Cajon/San Diego
Loews Coronado Bay Resort
Exterior

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1036)
"Beautiful quiet hotel."
The price is 5.248.824 ₫
7.026.566 ₫ total
includes taxes & fees
26 Oct - 27 Oct
Loews Coronado Bay Resort
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter
Lobby sitting area

AC Hotel by Marriott San Diego Downtown Gaslamp Quarter

4.0 star property
8.8 out of 10, Excellent, (932)
"Would definitely stay again!"
The price is 4.246.536 ₫
4.923.646 ₫ total
includes taxes & fees
14 Oct - 15 Oct
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter
The Bristol Hotel San Diego
Property entrance

The Bristol Hotel San Diego

3.5 star property
8.4 out of 10, Very good, (1385)
"Very nice staff from check in, clean rooms, quiet and comfortable. "
The Bristol Hotel San Diego
Days Inn by Wyndham Chula Vista/San Diego
Lobby

Days Inn by Wyndham Chula Vista/San Diego

2.0 star property
6.2 out of 10, (1004)
"The staff was incredibly helpful"
The price is 1.883.246 ₫
2.075.263 ₫ total
includes taxes & fees
13 Oct - 14 Oct
Days Inn by Wyndham Chula Vista/San Diego
Days Inn by Wyndham San Diego-East/El Cajon
Standard Room, 1 King Bed, Smoking | Desk, laptop workspace, iron/ironing board, free WiFi

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1004)
"Place was nice and comfy. Decent stay at a very genuine price. "
The price is 2.082.649 ₫
2.294.976 ₫ total
includes taxes & fees
13 Oct - 14 Oct
Days Inn by Wyndham San Diego-East/El Cajon
Best Western Plus La Mesa San Diego
Lobby

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very good, (1002)
"Excelent place to stay."
The price is 2.618.483 ₫
2.880.331 ₫ total
includes taxes & fees
26 Oct - 27 Oct
Best Western Plus La Mesa San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Otay Mesa

Find the best Otay Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Pacific Beach Park showing a beach

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Belmont Park featuring a park and rides

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Otay Mesa Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"It was centrally located,. I had private car and they had parking in. It was perfect for me, the rooms were comfortable and clean. Pretty view."
Milagros 3-night trip
Posted 3 days ago
The DEXTRO Little Italy, BW Premier Collection

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! Most room reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.

What is there to do in this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.