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Top Trending Hotels Near Otay Mesa, San Diego

Exterior
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
Otay Mesa
8.0 out of 10, Very good, (1534)
"Good comfortable beds good breakfast "
United States
Andrey
The price is 3.399.537 ₫
3.866.974 ₫ total
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Desk, laptop workspace, blackout curtains, iron/ironing board
Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa

2.5 star property
Otay Mesa
7.2 out of 10, Good, (1001)
"Clean, friendly staff and yummy breakfast :)"
United States
Iliana
The price is 2.608.650 ₫
2.967.340 ₫ total
includes taxes & fees
22 Nov - 23 Nov
Quality Suites San Diego Otay Mesa
Exterior
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
Gaslamp Quarter, 24.1 km from Otay Mesa
9.0 out of 10, Wonderful, (1208)
"Very friendly staff!"
United States
Glenn
The price is 3.561.608 ₫
4.129.506 ₫ total
includes taxes & fees
21 Nov - 22 Nov
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Serves dinner and happy hour
The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
24.3 km from Otay Mesa
9.0 out of 10, Wonderful, (2654)
"Beautiful and historic, very comfortable. Would definitely stay there again. "
United States
Amy
The Horton Grand, Downtown/Gaslamp Quarter
Outdoor pool
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4.0 star property
Gaslamp Quarter, 24 km from Otay Mesa
9.0 out of 10, Wonderful, (3085)
"Our stay was great! Would stay here again"
United States
Carla
The price is 5.667.885 ₫
7.780.628 ₫ total
includes taxes & fees
21 Nov - 22 Nov
Hard Rock Hotel San Diego
Rooftop terrace
Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 24.5 km from Otay Mesa
8.6 out of 10, Excellent, (2034)
"staff was very friendly and hotel was clean"
United States
Stephany
The price is 2.767.065 ₫
3.208.274 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Palihotel San Diego Gaslamp Quarter
Exterior
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter

AC Hotel by Marriott San Diego Downtown Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 24.4 km from Otay Mesa
8.8 out of 10, Excellent, (953)
"Great spot "
United States
George
The price is 3.373.184 ₫
3.911.038 ₫ total
includes taxes & fees
14 Dec - 15 Dec
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 star property
25.7 km from Otay Mesa
8.4 out of 10, Very good, (6032)
"I enjoyed my stay."
United States
Kevin
The price is 3.561.203 ₫
4.893.186 ₫ total
includes taxes & fees
25 Nov - 26 Nov
Wyndham San Diego Bayside
Lobby
El Cordova Hotel on Coronado Island

El Cordova Hotel on Coronado Island

3.5 star property
23.5 km from Otay Mesa
8.8 out of 10, Excellent, (1002)
"Thank you - great spot! I will stay again ⭐️ "
United States
Donna
The price is 3.323.377 ₫
4.452.867 ₫ total
includes taxes & fees
30 Nov - 1 Dec
El Cordova Hotel on Coronado Island
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 star property
16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3409)
"Clean, staff friendly, great place for a stay"
United States
Derrick
The price is 3.059.847 ₫
3.371.799 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Best Western Plus Marina Gateway Hotel
Lobby
Gaslamp Plaza Suites

Gaslamp Plaza Suites

3.5 star property
Gaslamp Quarter, 24.6 km from Otay Mesa
8.8 out of 10, Excellent, (1001)
"Had a great stay "
United States
Robert
The price is 2.925.183 ₫
3.327.396 ₫ total
includes taxes & fees
9 Dec - 10 Dec
Gaslamp Plaza Suites
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
Gaslamp Quarter, 24.2 km from Otay Mesa
9.4 out of 10, Exceptional, (1000)
"The room was immaculate, the staff were helpful and friendly and our stay was so wonderful. "
United States
Samantha Erin
The price is 2.933.089 ₫
4.162.457 ₫ total
includes taxes & fees
23 Nov - 24 Nov
Staypineapple, Hotel Z, Gaslamp San Diego
Outdoor pool, pool loungers
Best Western Plus Suites Hotel Coronado Island

Best Western Plus Suites Hotel Coronado Island

2.5 star property
24.1 km from Otay Mesa
8.8 out of 10, Excellent, (1005)
"Good to spend a night or two-- nice staff-- friendly ad awesome breakfast"
United States
MICHELE
The price is 4.024.630 ₫
4.427.093 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Best Western Plus Suites Hotel Coronado Island
Front of property
The Sofia Hotel

The Sofia Hotel

3.5 star property
24.9 km from Otay Mesa
8.4 out of 10, Very good, (1623)
"Excellent stay all-around!"
United States
Nalani
The Sofia Hotel
Property entrance
The Bristol Hotel San Diego

The Bristol Hotel San Diego

3.5 star property
24.9 km from Otay Mesa
8.6 out of 10, Excellent, (1430)
"Bed so comfy and staff very friendly room very nice"
United States
JODI
The price is 2.933.089 ₫
3.400.770 ₫ total
includes taxes & fees
19 Nov - 20 Nov
The Bristol Hotel San Diego
Lobby
Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego

2.5 star property
24.5 km from Otay Mesa
8.2 out of 10, Very good, (1007)
"Great place "
United States
Fadi
The price is 2.508.806 ₫
2.759.686 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Best Western Plus La Mesa San Diego
Pillow-top beds, in-room safe, desk, blackout curtains
Holiday Inn Express San Diego Downtown by IHG

Holiday Inn Express San Diego Downtown by IHG

2.5 star property
24.9 km from Otay Mesa
8.4 out of 10, Very good, (1528)
"Very nice hotel. "
United States
James
The price is 2.714.359 ₫
3.147.163 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Holiday Inn Express San Diego Downtown by IHG
Presidential Suite, 2 Bedrooms, Non Smoking | Living room | 36-inch LCD TV with digital channels, TV, pay films
Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

4.0 star property
24.7 km from Otay Mesa
9.0 out of 10, Wonderful, (845)
"Lovely hotel. Really enjoyed the complimentary bottle of wine as well as how convenient it was to walk to restaurants & bars . "
United States
Gisselle
The price is 3.302.031 ₫
4.897.945 ₫ total
includes taxes & fees
24 Nov - 25 Nov
Alma San Diego Downtown, a Tribute Portfolio Hotel
2 outdoor pools, open 6 AM to 10:00 PM, pool cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4.0 star property
24.5 km from Otay Mesa
9.2 out of 10, Wonderful, (1916)
"The hotel was beautiful and the staff was amazingly kind, warm, and accommodating!"
United States
Leila
The price is 4.189.650 ₫
6.243.436 ₫ total
includes taxes & fees
25 Nov - 26 Nov
Marriott Marquis San Diego Marina
Exterior
Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 24.1 km from Otay Mesa
9.0 out of 10, Wonderful, (1131)
"Great Hotel - good position and very helpful staff. "
United Kingdom
James
The price is 4.150.597 ₫
5.881.814 ₫ total
includes taxes & fees
23 Nov - 24 Nov
Margaritaville Hotel San Diego Gaslamp Quarter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels in Otay Mesa with free breakfast

Standard Room, 1 King Bed, Smoking | Desk, laptop workspace, iron/ironing board, free WiFi
Days Inn by Wyndham San Diego-East/El Cajon
Days Inn by Wyndham San Diego-East/El Cajon
2.0 star property
  • Breakfast included
7.6 out of 10, Good, (1000)
The price is 1.724.608 ₫
1.900.626 ₫ total
includes taxes & fees
25 Nov - 26 Nov
Days Inn by Wyndham San Diego-East/El Cajon
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Top guest rated hotels in Otay Mesa

Desk, laptop workspace, blackout curtains, iron/ironing board
Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay Mesa
2.5 star property
    7.2 out of 10, Good, (1001)
    The price is 2.608.650 ₫
    2.967.340 ₫ total
    includes taxes & fees
    22 Nov - 23 Nov
    Quality Suites San Diego Otay Mesa
    See more properties

    Where to stay in Otay Mesa

    Find the best Otay Mesa areas for the activities you enjoy most.

    Downtown San Diego

    Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

    Gaslamp Quarter featuring a bar, night scenes and street scenes

    Gaslamp Quarter

    Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.

    Pacific Beach Park showing a beach

    Pacific Beach

    The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

    Belmont Park featuring a park and rides

    Mission Beach

    If you're spending some time in Mission Beach, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

    Ocean Beach

    Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

    Top Otay Mesa Hotel Reviews

    Courtyard by Marriott San Diego Downtown Little Italy

    Courtyard by Marriott San Diego Downtown Little Italy

    10/10 Excellent
    "Nice clean room with nice balcony. Nice neighborhood. Friendly staff. "
    Julie 2-night trip
    Posted 17 hours ago
    Courtyard by Marriott San Diego Downtown Little Italy

    Explore a world of travel with Expedia

    Frequently asked questions

    What's it like in Otay Mesa?
    Otay Mesa is a neighbourhood that travellers like for its beaches, restaurants and shopping.
    If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
    Yes! Most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view top deals in Otay Mesa.
    What is there to do in this San Diego neighbourhood?
    A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.