Search Hotels in Otay Mesa West, San Diego

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Top Trending Hotels Near Otay Mesa West, San Diego

Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

3.5 star property
10.5 km from Otay Mesa West
9.2 out of 10, Wonderful, (3407)
"Clean, staff friendly, great place for a stay"
United States
Derrick
The price is 3.059.499 ₫
3.371.415 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Best Western Plus Marina Gateway Hotel
Lobby
El Cordova Hotel on Coronado Island

El Cordova Hotel on Coronado Island

3.5 star property
16.4 km from Otay Mesa West
8.8 out of 10, Excellent, (1004)
"Thank you - great spot! I will stay again ⭐️ "
United States
Donna
The price is 3.322.999 ₫
4.452.360 ₫ total
includes taxes & fees
30 Nov - 1 Dec
El Cordova Hotel on Coronado Island
Serves dinner and happy hour
The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
17.8 km from Otay Mesa West
9.0 out of 10, Wonderful, (2656)
"Beautiful and historic, very comfortable. Would definitely stay there again. "
United States
Amy
The Horton Grand, Downtown/Gaslamp Quarter
Exterior
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
Gaslamp Quarter, 17.6 km from Otay Mesa West
9.0 out of 10, Wonderful, (1208)
"Very friendly staff!"
United States
Glenn
The price is 3.561.203 ₫
4.129.037 ₫ total
includes taxes & fees
20 Nov - 21 Nov
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Rooftop terrace
Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 18.1 km from Otay Mesa West
8.6 out of 10, Excellent, (2034)
"staff was very friendly and hotel was clean"
United States
Stephany
The price is 3.030.250 ₫
3.513.246 ₫ total
includes taxes & fees
23 Nov - 24 Nov
Palihotel San Diego Gaslamp Quarter
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 star property
19.2 km from Otay Mesa West
8.4 out of 10, Very good, (6049)
"I enjoyed my stay."
United States
Kevin
The price is 3.561.203 ₫
4.893.186 ₫ total
includes taxes & fees
23 Nov - 24 Nov
Wyndham San Diego Bayside
Outdoor pool
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4.0 star property
Gaslamp Quarter, 17.5 km from Otay Mesa West
9.0 out of 10, Wonderful, (3079)
"Our stay was great! Would stay here again"
United States
Carla
The price is 4.234.162 ₫
6.121.048 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Hard Rock Hotel San Diego
Outdoor pool, pool loungers
Best Western Plus Suites Hotel Coronado Island

Best Western Plus Suites Hotel Coronado Island

2.5 star property
17.3 km from Otay Mesa West
8.8 out of 10, Excellent, (1005)
"Good to spend a night or two-- nice staff-- friendly ad awesome breakfast"
United States
MICHELE
The price is 4.024.172 ₫
4.426.589 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Best Western Plus Suites Hotel Coronado Island
Lobby
Gaslamp Plaza Suites

Gaslamp Plaza Suites

3.5 star property
Gaslamp Quarter, 18.2 km from Otay Mesa West
8.8 out of 10, Excellent, (1005)
"Had a great stay "
United States
Robert
The price is 2.924.850 ₫
3.327.017 ₫ total
includes taxes & fees
9 Dec - 10 Dec
Gaslamp Plaza Suites
Front of property
The Sofia Hotel

The Sofia Hotel

3.5 star property
18.5 km from Otay Mesa West
8.4 out of 10, Very good, (1633)
"Excellent stay all-around!"
United States
Nalani
The Sofia Hotel
Property entrance
The Bristol Hotel San Diego

The Bristol Hotel San Diego

3.5 star property
18.5 km from Otay Mesa West
8.6 out of 10, Excellent, (1429)
"Nice staff, comfortable beds"
United States
Amber
The Bristol Hotel San Diego
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
Gaslamp Quarter, 17.8 km from Otay Mesa West
9.4 out of 10, Exceptional, (1003)
"The room was immaculate, the staff were helpful and friendly and our stay was so wonderful. "
United States
Samantha Erin
The price is 2.815.223 ₫
4.025.625 ₫ total
includes taxes & fees
23 Nov - 24 Nov
Staypineapple, Hotel Z, Gaslamp San Diego
Presidential Suite, 2 Bedrooms, Non Smoking | Living room | 36-inch LCD TV with digital channels, TV, pay films
Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

4.0 star property
18.3 km from Otay Mesa West
9.0 out of 10, Wonderful, (845)
"Lovely hotel. Really enjoyed the complimentary bottle of wine as well as how convenient it was to walk to restaurants & bars . "
United States
Gisselle
The price is 3.346.450 ₫
4.949.325 ₫ total
includes taxes & fees
27 Nov - 28 Nov
Alma San Diego Downtown, a Tribute Portfolio Hotel
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Diego Mission Bay

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

3.0 star property
North Pacific Beach, 29.8 km from Otay Mesa West
8.0 out of 10, Very good, (1407)
"Great place We will stay here again. "
United States
Derek
The price is 2.689.808 ₫
3.092.459 ₫ total
includes taxes & fees
23 Nov - 24 Nov
La Quinta Inn & Suites by Wyndham San Diego Mission Bay
Exterior
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 star property
22.1 km from Otay Mesa West
9.2 out of 10, Wonderful, (3108)
"Great staff and beautiful location. "
United States
elaine
The price is 2.869.515 ₫
3.298.364 ₫ total
includes taxes & fees
24 Nov - 25 Nov
Bay Club Hotel & Marina
Check-in/check-out kiosk
Urban Boutique Hotel

Urban Boutique Hotel

3.0 star property
Little Italy, 19.3 km from Otay Mesa West
8.6 out of 10, Excellent, (1279)
"Alwsys clean , great staff andvperfect location"
United States
Colleen
Urban Boutique Hotel
Exterior
La Pensione Hotel

La Pensione Hotel

3.0 star property
Little Italy, 19.4 km from Otay Mesa West
8.6 out of 10, Excellent, (1900)
"Friendly staff, very nice room, great location!"
United States
Lisa
La Pensione Hotel
Outdoor pool, pool umbrellas, pool loungers
Lamplighter Inn & Suites at SDSU

Lamplighter Inn & Suites at SDSU

2.5 star property
21 km from Otay Mesa West
9.0 out of 10, Wonderful, (1297)
"Hotel was great for a quick stay. Friendly staff and clean rooms. "
United States
Veronica
The price is 2.863.711 ₫
3.228.834 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Lamplighter Inn & Suites at SDSU
Exterior
Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

4.0 star property
Gaslamp Quarter, 17.6 km from Otay Mesa West
9.0 out of 10, Wonderful, (1131)
"Great Hotel - good position and very helpful staff. "
United Kingdom
James
The price is 4.150.125 ₫
5.881.146 ₫ total
includes taxes & fees
23 Nov - 24 Nov
Margaritaville Hotel San Diego Gaslamp Quarter
Garden
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4.0 star property
22.9 km from Otay Mesa West
9.2 out of 10, Wonderful, (2938)
"Great hotel"
United States
Michael
The price is 4.637.589 ₫
5.330.677 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Legacy Resort Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter featuring a bar, night scenes and street scenes

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.

Pacific Beach Park showing a beach

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Belmont Park featuring a park and rides

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Otay Mesa West Hotel Reviews

Hampton Inn & Suites by Hilton San Diego SeaWorld

Hampton Inn & Suites by Hilton San Diego SeaWorld

10/10 Excellent
"Hotel, inside and outside clean. Rooms, lobby and gym and hallways clean, spacious, sufficient elevators. Modern, new and spacious. Gym was real nice with good equipment. The staff was real professional and friendly. Breakfast was delicious. The streets/areas/traffic near me of the hotel were sketchy."
Catalina 1-night trip
Posted 3 days ago
Hampton Inn & Suites by Hilton San Diego SeaWorld

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Frequently asked questions

What is Otay Mesa West like?
Otay Mesa West is a neighbourhood that travellers like for its cathedral.
If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?
Yes! The majority of room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.
What is there to do around this San Diego neighbourhood?
A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.
How can I get around Otay Mesa West and the greater San Diego area?
Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.