Photo by Leonardo De Leon

Search Hotels in Otay Mesa West, San Diego

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top Trending Hotels Near Otay Mesa West, San Diego

Hotel Zindel

2.0 star property
7.6 out of 10, Good, (478)
"Great location"
Hotel Zindel

Best Western Plus Suites Hotel Coronado Island

2.5 star property
8.8 out of 10, Excellent, (1006)
"Great location"
The price is 5.617.120 ₫
6.178.832 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Best Western Plus Suites Hotel Coronado Island

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.6 out of 10, Excellent, (1452)
"Excellent hotel!"
The price is 2.586.969 ₫
3.735.688 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Palihotel San Diego Gaslamp Quarter

Wyndham San Diego Bayside

4.0 star property
8.4 out of 10, Very good, (5693)
"Beautiful stay!"
The price is 3.975.832 ₫
5.367.569 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Wyndham San Diego Bayside

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2346)
"Love this hotel "
The Horton Grand, Downtown/Gaslamp Quarter

El Cordova Hotel on Coronado Island

3.5 star property
8.8 out of 10, Excellent, (1002)
"Nice place "
El Cordova Hotel on Coronado Island

Super 8 by Wyndham El Cajon/San Diego

2.0 star property
7.6 out of 10, Good, (1004)
"Nice staff and quiet "
The price is 2.328.272 ₫
2.561.099 ₫ total
includes taxes & fees
25 Jun - 26 Jun
Super 8 by Wyndham El Cajon/San Diego

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very good, (1010)
"Stayed here while visiting friends, best in the area and very comfortable. "
The price is 3.219.339 ₫
3.541.273 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Best Western Plus La Mesa San Diego

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
9.0 out of 10, Wonderful, (1004)
"It was great staying there. I am thinking of going back in a couple of weeks."
The price is 4.170.244 ₫
4.835.190 ₫ total
includes taxes & fees
26 Jun - 27 Jun
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1002)
"Great place!"
The price is 2.978.934 ₫
3.282.636 ₫ total
includes taxes & fees
26 Jun - 27 Jun
Days Inn by Wyndham San Diego-East/El Cajon

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3114)
"Great place to stay, amazing beds!"
The price is 4.680.323 ₫
5.157.481 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Best Western Plus Marina Gateway Hotel

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1006)
"Great place to stay! It’s so beautiful and very relaxing! "
The price is 7.046.455 ₫
9.037.537 ₫ total
includes taxes & fees
2 Jul - 3 Jul
Loews Coronado Bay Resort

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1005)
"Location was perfect "
The price is 3.693.495 ₫
4.201.350 ₫ total
includes taxes & fees
25 Jun - 26 Jun
Gaslamp Plaza Suites

Hard Rock Hotel San Diego

4.0 star property
8.8 out of 10, Excellent, (2697)
"Great location"
The price is 5.385.599 ₫
7.443.677 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Hard Rock Hotel San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
9.4 out of 10, Exceptional, (1000)
"Nice place to stay "
The price is 2.567.401 ₫
3.731.958 ₫ total
includes taxes & fees
7 Jul - 8 Jul
Staypineapple, Hotel Z, Gaslamp San Diego

The Sofia Hotel

3.5 star property
8.4 out of 10, Very good, (1477)
"Old timey vibe , perfect for a quick stay "
The Sofia Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

4.0 star property
9.0 out of 10, Wonderful, (642)
"Staff were kind and food was great. "
The price is 3.206.268 ₫
4.750.901 ₫ total
includes taxes & fees
8 Jul - 9 Jul
Alma San Diego Downtown, a Tribute Portfolio Hotel

Lamplighter Inn & Suites at SDSU

2.5 star property
9.2 out of 10, Wonderful, (1171)
"Nice place to stay "
Lamplighter Inn & Suites at SDSU

The Bristol Hotel San Diego

3.5 star property
8.4 out of 10, Very good, (1332)
"Awesome hotel"
The Bristol Hotel San Diego

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

3.0 star property
8.0 out of 10, Very good, (1274)
"For the price the hotel is clean, nice beds, and the staff is very pleasant. Would stay here again"
The price is 3.886.202 ₫
4.467.947 ₫ total
includes taxes & fees
6 Jul - 7 Jul
La Quinta Inn & Suites by Wyndham San Diego Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas for the activities you enjoy most.
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Seaport Village and Petco Park are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Mission Beach map

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach map

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Gaslamp Quarter map

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Ocean Beach map

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Ocean Beach.

Frequently asked questions

What is Otay Mesa West like?

Otay Mesa West is a neighbourhood that travellers like for its cathedral.

How many hotels are there in the Otay Mesa West area?

When you want to find places to stay in San Diego, start by booking one of Expedia's 5 hotels and other accommodation options in Otay Mesa West.

If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?

Yes! The majority of room reservations are refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.

What is there to do around this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.

How can I get around Otay Mesa West and the greater San Diego area?

Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.