Santa Ana Travel Guide

Panama City

A gazebo with columns, a large tree with hanging roots, and a building in the background.
A waterfront cityscape with numerous boats docked along the shore and a clear sky.

Stay near popular Santa Ana attractions


Top hotels in Santa Ana

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste Panama City Provincia de Panamá
The price is 2.283.724 ₫ per night from 30 Jun to 1 Jul
2.283.724 ₫
3.301.036 ₫ total
30 Jun - 1 Jul
includes taxes & fees
Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
9/10 Wonderful! (100 reviews)
"Great layout with modern convenience for my family, sofa bed was generous and comfortable. Thoughtful kitchen tools made our stay easy."

Reviewed on 20 Jun 2026

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
The price is 3.655.566 ₫ per night from 30 Jun to 1 Jul
3.655.566 ₫
4.021.123 ₫ total
30 Jun - 1 Jul
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (5,658 reviews)
"Great hotel, I will come back again."

Reviewed on 29 Jun 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
The price is 3.339.846 ₫ per night from 9 Jul to 10 Jul
3.339.846 ₫
3.847.397 ₫ total
9 Jul - 10 Jul
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (2,604 reviews)
"All ok"

Reviewed on 29 Jun 2026

Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
The price is 7.875.199 ₫ per night from 14 Jul to 15 Jul
7.875.199 ₫
7.875.199 ₫ total
14 Jul - 15 Jul
includes taxes & fees
Stay at this beach resort in Veracruz. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the pool and the helpful staff in their reviews. ...
7.6/10 Good! (1,023 reviews)
"The best and clean is pool area and beautifull gardens, room nice and clean but the bathroom did not like bathroom door and entrance door rusty and with holes very ugly shower area needs a deep cleaning the area is very humid so the first room we got smelled very very bad so we asked for a change. ..."

Reviewed on 27 Jun 2026

Dreams Playa Bonita Panama - All Inclusive
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
The price is 1.491.097 ₫ per night from 30 Jun to 1 Jul
1.491.097 ₫
1.640.207 ₫ total
30 Jun - 1 Jul
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and room service. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (1,914 reviews)
"Nice place! Clean, quiet, good location. For us this was great value and a great place to stay!"

Reviewed on 28 Jun 2026

Principe Hotel and Suites
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Plaza de la Independencia Casco Viejo Panama City Panama
The price is 4.588.738 ₫ per night from 19 Jul to 20 Jul
4.588.738 ₫
5.047.638 ₫ total
19 Jul - 20 Jul
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and 3 restaurants. Our guests praise the helpful staff and the clean rooms in their ...
9.2/10 Wonderful! (1,007 reviews)
"We really enjoyed our stay in one of the family rooms. The hotel is beautiful and well maintained. The breakfast was really good. The only reason I did not rate 5 star was that the air conditioning control was not working well and the room was really cold. The staff was very friendly."

Reviewed on 27 Jun 2026

Central Hotel Panama Casco Viejo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.



Santa Ana Travel Guide

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