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Check availability on South San Antonio Business Hotels

Tonight
6 Dec - 7 Dec
Tomorrow
7 Dec - 8 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Top South San Antonio Business Hotels

Exterior
Econo Lodge Inn & Suites Near Lackland AFB

Econo Lodge Inn & Suites Near Lackland AFB

3.0 star property
South San Antonio
8.4 out of 10, Very good, (563)
"great stay!"
United States
Asharia
The price is 1.568.335 ₫
1.830.910 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Econo Lodge Inn & Suites Near Lackland AFB
Lobby
Best Western Plus Palo Alto Inn & Suites

Best Western Plus Palo Alto Inn & Suites

2.5 star property
South San Antonio
8.2 out of 10, Very good, (1003)
"This is a solid hotel if you need to stay on the far south side to travel to Somerset and Poteet but also want to be convenient to San Antonio. I have stayed here before and would stay here again. Everyone was very nice and the rooms are good sized and clean, and breakfast was better than I expected it to be. Good coffee, too. "
United States
Sofia
The price is 2.372.406 ₫
2.769.784 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Best Western Plus Palo Alto Inn & Suites
Lobby
Days Inn by Wyndham San Antonio at Palo Alto

Days Inn by Wyndham San Antonio at Palo Alto

2.5 star property
South San Antonio
6.8 out of 10, (721)
"The interior of the room was clean and the property staff were courteous. "
United States
Bryan
The price is 1.232.470 ₫
1.438.909 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Days Inn by Wyndham San Antonio at Palo Alto
Water park
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

3.5 star property
Far West Side
9.0 out of 10, Wonderful, (1268)
"Great place!"
United States
Heath
The price is 1.982.498 ₫
3.432.283 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Outdoor pool, pool loungers
Hampton Inn San Antonio-Downtown (River Walk)

Hampton Inn San Antonio-Downtown (River Walk)

2.5 star property
Downtown San Antonio
8.4 out of 10, Very good, (2407)
"Great staff, close to the River Walk and the San Antonio Convention Center."
United States
Yunwei
The price is 2.076.086 ₫
2.454.121 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hampton Inn San Antonio-Downtown (River Walk)
Exterior
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

3.0 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (4090)
"Very nice stay."
United States
Anthony
The price is 3.163.296 ₫
3.739.328 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Drury Plaza Hotel San Antonio Riverwalk
Terrace/patio
Tru by Hilton San Antonio North

Tru by Hilton San Antonio North

2.5 star property
San Antonio
8.8 out of 10, Excellent, (619)
"I really enjoyed my stay. "
United States
Chris
The price is 1.855.955 ₫
2.166.827 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru by Hilton San Antonio North
Lobby
Menger Hotel

Menger Hotel

3.5 star property
Downtown San Antonio
9.0 out of 10, Wonderful, (3557)
"Historic and classy, and you can beat the location."
United States
Warren
The price is 2.471.531 ₫
2.921.572 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Menger Hotel
Lobby
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1001)
"The room is clean and the hotel staff are all nice including the staff from the restourant"
United States
Frank Charles
The price is 2.346.307 ₫
2.788.309 ₫ total
includes taxes & fees
11 Dec - 12 Dec
San Antonio Marriott Northwest Medical Center
Free daily buffet breakfast
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

3.0 star property
Downtown San Antonio
7.8 out of 10, Good, (3761)
"The room is clean and staff is friendly"
United States
Michelle
The price is 1.874.409 ₫
2.677.336 ₫ total
includes taxes & fees
14 Dec - 15 Dec
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top South San Antonio Hotel Reviews

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

10/10 Excellent
"Incredible location, beautiful room, loved all of it!"
Eden 4-night trip
Posted 2 days ago
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

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Frequently asked questions

Why book your business-friendly hotel in South San Antonio with Expedia?
With conveniences like room service, conference rooms and on-site restaurants, our business-friendly stays come with everything you'll need to get the job done — and then relax! Enter your travel dates and destination and Expedia will help you plan the rest.
How can I find cheap business-friendly hotels in South San Antonio?
When you're travelling for work in South San Antonio, our "business friendly" filter will help you find the right hotel. From dependable WiFi to workspaces and meeting rooms, they have the amenities you need for a productive and comfortable stay. You can also refine your search by your preferred star rating and budget to see the cheapest properties.