Find hotels in South San Francisco, CA from 1.881.968 ₫

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for South San Francisco hotels

Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point
3.5 star property
The East Side
8.6 out of 10, Excellent, (1,308 reviews)
"It was a nice room with a great breakfast 😋 "
United States
Joshua Joseph
The price is 3.610.181 ₫
4.242.282 ₫ total
includes taxes & fees
13 Mar - 14 Mar
Embassy Suites by Hilton San Francisco Airport Oyster Point

Home2 Suites by Hilton San Francisco Airport North

Home2 Suites by Hilton San Francisco Airport North
3.0 star property
The East Side
8.8 out of 10, Excellent, (1,189 reviews)
"Had an amazing stay here, felt like home "
United States
Miguel
The price is 2.903.171 ₫
3.402.507 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Home2 Suites by Hilton San Francisco Airport North

DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd
4.0 star property
South San Francisco
8.4 out of 10, Very good, (2,154 reviews)
"Clean room, safe, excellent service"
United States
Nathan
The price is 2.722.762 ₫
3.215.583 ₫ total
includes taxes & fees
27 Mar - 28 Mar
DoubleTree by Hilton San Francisco South Airport Blvd

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
4.0 star property
Oyster Point
9.2 out of 10, Wonderful, (1,001 reviews)
"Great place to stay and staff are helpful. "
United States
Smile
The price is 3.039.846 ₫
3.635.419 ₫ total
includes taxes & fees
5 Apr - 6 Apr
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
3.0 star property
The East Side
9.0 out of 10, Wonderful, (460 reviews)
"Clean room, helpful staff, complimentary breakfast. "
United States
Veronica
The price is 2.933.616 ₫
3.437.527 ₫ total
includes taxes & fees
3 Apr - 4 Apr
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.0 out of 10, Very good, (2,003 reviews)
"Pleasant stay "
United States
Alok
The price is 2.983.383 ₫
3.495.462 ₫ total
includes taxes & fees
3 Apr - 4 Apr
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Days Inn by Wyndham San Francisco S/Oyster Point Airport

Days Inn by Wyndham San Francisco S/Oyster Point Airport
2.0 star property
Paradise Valley
8.8 out of 10, Excellent, (6 reviews)
"The room was nice and clean. "
United States
Kyle
The price is 2.425.855 ₫
2.910.657 ₫ total
includes taxes & fees
7 Mar - 8 Mar
Days Inn by Wyndham San Francisco S/Oyster Point Airport

Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel
3.0 star property
South San Francisco
8.4 out of 10, Very good, (1,730 reviews)
"Great breakfast and walking distance to where I was working."
United States
Karyn
The price is 2.303.842 ₫
2.726.436 ₫ total
includes taxes & fees
7 Mar - 8 Mar
Best Western Plus Grosvenor Airport Hotel

Hilton Garden Inn San Francisco Arpt North

Hilton Garden Inn San Francisco Arpt North
3.0 star property
The East Side
8.6 out of 10, Excellent, (1,004 reviews)
"rooms are spacious and staff is very helpful"
United States
RAVINDER
The price is 2.198.378 ₫
2.592.408 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Hilton Garden Inn San Francisco Arpt North

Hampton Inn San Francisco Airport

Hampton Inn San Francisco Airport
2.5 star property
The East Side
8.8 out of 10, Excellent, (1,003 reviews)
"Amazing place, 100% recommend "
United States
Ana catherine
The price is 2.922.023 ₫
3.457.754 ₫ total
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn San Francisco Airport

Holiday Inn Express San Francisco-Airport North by IHG

Holiday Inn Express San Francisco-Airport North by IHG
2.5 star property
South San Francisco
8.2 out of 10, Very good, (1,007 reviews)
"Great room delicious breakfast wonderful customer service "
United States
Stephanie
The price is 2.451.665 ₫
3.189.798 ₫ total
includes taxes & fees
15 Mar - 16 Mar
Holiday Inn Express San Francisco-Airport North by IHG

Hotel Focus SFO

Hotel Focus SFO
3.0 star property
The East Side
7.6 out of 10, Good, (1,544 reviews)
"Good place to stay"
United States
Ricardo
The price is 2.100.416 ₫
2.479.807 ₫ total
includes taxes & fees
4 Apr - 5 Apr
Hotel Focus SFO

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North
2.0 star property
South San Francisco
5.8 out of 10, (3,270 reviews)
"Staff were very pleasant "
United States
Karla
The price is 1.571.580 ₫
1.881.968 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Travelodge by Wyndham San Francisco Airport North

Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta Select San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point
8.6 out of 10, Excellent, (1,983 reviews)
"I love this hotel :)"
United States
Daniel
The price is 2.671.686 ₫
3.190.570 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
3.0 star property
Oyster Point
8.4 out of 10, Very good, (1,009 reviews)
"It was a great stay, clean, comfortable wirh everything you need!"
United States
Chee
The price is 2.881.230 ₫
3.420.544 ₫ total
includes taxes & fees
1 Apr - 2 Apr
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

Comfort Inn and Suites San Francisco Airport North

Comfort Inn and Suites San Francisco Airport North
2.5 star property
The East Side
7.8 out of 10, Good, (1,007 reviews)
"Hotel is rather old but very clean and comfortable. Staff was very friendly. Fitness area could use some work - treadmill didn’t work at all. "
United States
Gwyn M
The price is 2.857.089 ₫
3.349.540 ₫ total
includes taxes & fees
7 Mar - 8 Mar
Comfort Inn and Suites San Francisco Airport North

Four Points by Sheraton Hotel & Suites San Francisco Airport

Four Points by Sheraton Hotel & Suites San Francisco Airport
3.0 star property
South San Francisco
7.8 out of 10, Good, (1,000 reviews)
"all good; the staff, the room, the breakfast; i would definitely stay there again."
United States
Bennett
The price is 2.304.104 ₫
2.713.911 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Four Points by Sheraton Hotel & Suites San Francisco Airport

Larkspur Landing Extended Stay Suites South San Francisco

Larkspur Landing Extended Stay Suites South San Francisco
3.0 star property
The East Side
7.8 out of 10, Good, (1,003 reviews)
"Friendly staff and the room was clean. "
United States
Sia
The price is 2.560.366 ₫
3.027.697 ₫ total
includes taxes & fees
8 Mar - 9 Mar
Larkspur Landing Extended Stay Suites South San Francisco

Rodeway Inn South San Francisco Airport

Rodeway Inn South San Francisco Airport
2.0 star property
South San Francisco
7.2 out of 10, Good, (1,005 reviews)
"The best hotel "
United States
Taner
The price is 1.963.725 ₫
2.318.766 ₫ total
includes taxes & fees
9 Mar - 10 Mar
Rodeway Inn South San Francisco Airport

Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (990 reviews)
"Very clean room, friendly staff and secure parking."
United States
Christopher
The price is 2.593.107 ₫
3.041.007 ₫ total
includes taxes & fees
8 Mar - 9 Mar
Airport Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Where to stay in South San Francisco

Find the best South San Francisco areas for the activities you enjoy most. Learn more about South San Francisco
Learn more about South San Francisco

Downtown South San Francisco

City centre South San Francisco blends business energy with cultural richness just minutes from San Francisco proper. Modern biotech campuses stand alongside vibrant ethnic markets on Grand Avenue. The area hums with professional activity while celebrating its diverse heritage through colourful murals. This well-connected hub offers excellent transport options via BART and Caltrain stations. Authentic dining reflects the area's Hispanic and Asian communities. After business hours, the atmosphere becomes quietly residential with limited evening entertainment.

Oyster Point

Oyster Point blends sleek biotech campuses with refreshing waterfront beauty along San Francisco Bay. Modern glass buildings reflect the calm waters where walking paths invite you to explore. The area showcases contemporary plazas and public art installations throughout the business district. Corporate lunch spots serve the weekday crowd while evening options remain limited. The Bay Trail offers panoramic views and peaceful walks away from the office buzz. Visitors can observe both cutting-edge architecture and natural bay ecosystems during business hours.

The East Side

The East Side of South San Francisco blends cultural diversity with suburban charm just minutes from San Francisco Bay. Hispanic and Asian communities contribute authentic flavours to local eateries along Grand Avenue. Views of San Bruno Mountain create a distinctive backdrop for this working-class area. Visitors can explore Orange Memorial Park's recreational areas or hike nearby mountain trails. Budget-conscious travellers appreciate the area's affordable dining options and practical accommodation. Easy connections to BART and Caltrain make exploring the greater Bay Area convenient without downtown's premium prices.

Paradise Valley

Paradise Valley offers a quiet retreat from San Francisco's hustle while keeping you connected to the Bay Area. This peaceful residential area boasts wide streets and modest homes where local families live their everyday lives. Travellers appreciate the genuine suburban atmosphere and significantly lower prices than city centre. Just minutes from San Francisco International Airport, Paradise Valley serves as a practical base for exploring the region. Small local parks provide green spaces for relaxation. Though lacking tourist attractions within its boundaries, the neighborhood's proximity to major highways makes Bay Area adventures easily accessible.

Avalon

Though Avalon may not have many top sights, you can venture to the surrounding area to see attractions like See's Candies and Artichoke Joe's Casino.

Stay near popular South San Francisco attractions

Learn more about South San Francisco

Perched on the edge of San Francisco Bay, this family-friendly city boasts a surprising castle and stunning mountain views. Foodies flock to local restaurants, while thrill-seekers race go-karts at K1 Speed or tour the famous See's Sweets factory.

#BVSBlue Aristodes Demetries, One Of Americas Best Known Sculptors Created This Steel Sculpture As A Symbol Of Cabot Cabot And Forbes Industrial Park. Situated 243 Feet Above Sea Level It Rises To A Be Seen From The Bay Bridge, The East Bay and SFO. Called The Wind Harp Locally. It emits eerie sounds when the wind 💨is at its strongest.
Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀
Open Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀

Top South San Francisco Hotel Reviews

More cheap stays in South San Francisco

Hotels in South San Francisco with star rating

Frequently asked questions

What's the weather like in South San Francisco?
The hottest months are usually September and August, with an average temperature of 17°C, while the coldest months are February and January, with an average of 11°C. Average annual precipitation for South San Francisco is 574 mm.