South San Francisco Holiday Rentals, San Francisco: Private House Rentals

An aerial view of San Francisco with the Golden Gate Bridge, hills, and the ocean.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in South San Francisco

Pet friendly

Pool

Apartment

Hot tub

Family friendly

Condo

Spa

Waterpark

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for South San Francisco hotels

1. Best Western Plus Grosvenor Airport Hotel

South San Francisco

Kenneth

2.837.570 ₫

3.342.631 ₫ total

includes taxes & fees

2 Oct - 3 Oct

2. Embassy Suites by Hilton San Francisco Airport Oyster Point

The East Side

jenny

3.827.142 ₫

4.492.997 ₫ total

includes taxes & fees

11 Sept - 12 Sept

Deluxe Suite, Multiple Beds, Accessible, Non Smoking (Mobility/Hearing Impaired Accessible)

3. La Quinta Inn & Suites by Wyndham San Francisco Airport N

Downtown South San Francisco

Juan

3.080.643 ₫

3.606.743 ₫ total

includes taxes & fees

20 Sept - 21 Sept

4. DoubleTree by Hilton San Francisco South Airport Blvd

South San Francisco

Mokihana

3.399.528 ₫

3.998.269 ₫ total

includes taxes & fees

11 Sept - 12 Sept

5. Sonesta Select San Francisco Airport Oyster Point Waterfront

Oyster Point

reginald

3.181.028 ₫

3.745.474 ₫ total

includes taxes & fees

20 Sept - 21 Sept

6. Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

The East Side

Shivakumar

3.590.933 ₫

4.192.945 ₫ total

includes taxes & fees

6 Sept - 7 Sept

7. Hotel Nova SFO

South San Francisco

Brenden

2.818.260 ₫

3.299.191 ₫ total

includes taxes & fees

6 Sept - 7 Sept

Suite, 1 Bedroom, Non Smoking | Living area

8. Home2 Suites by Hilton San Francisco Airport North

The East Side

Evelyn

3.399.528 ₫

3.972.773 ₫ total

includes taxes & fees

19 Sept - 20 Sept

9. Hampton Inn San Francisco Airport

The East Side

Ruben

3.036.839 ₫

3.589.069 ₫ total

includes taxes & fees

4 Oct - 5 Oct

10. Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

Oyster Point

Eric

3.783.775 ₫

4.462.637 ₫ total

includes taxes & fees

7 Sept - 8 Sept

11. AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

Oyster Point

Lauren

4.673.615 ₫

5.525.210 ₫ total

includes taxes & fees

11 Sept - 12 Sept

12. Airport Inn

Downtown South San Francisco

Kelly

2.862.925 ₫

3.350.392 ₫ total

includes taxes & fees

5 Sept - 6 Sept

13. Hilton Garden Inn San Francisco Arpt North

The East Side

Margy

2.918.987 ₫

3.420.467 ₫ total

includes taxes & fees

7 Sept - 8 Sept

14. Hotel Focus SFO

The East Side

Cesar

2.428.793 ₫

2.856.961 ₫ total

includes taxes & fees

27 Sept - 28 Sept

15. Holiday Inn Express San Francisco-Airport North by IHG

South San Francisco

REAGAN

2.559.919 ₫

3.313.720 ₫ total

includes taxes & fees

6 Sept - 7 Sept

16. Comfort Inn and Suites San Francisco Airport North

The East Side

Sarah

2.751.064 ₫

3.227.395 ₫ total

includes taxes & fees

6 Sept - 7 Sept

17. Travelodge by Wyndham San Francisco Airport North

South San Francisco

Alice

1.996.267 ₫

2.369.002 ₫ total

includes taxes & fees

9 Sept - 10 Sept

18. Four Points by Sheraton Hotel & Suites San Francisco Airport

South San Francisco

pyae

2.687.785 ₫

3.154.712 ₫ total

includes taxes & fees

20 Sept - 21 Sept

19. Inn By The SFO

Downtown South San Francisco

Ben

1.935.994 ₫

2.286.738 ₫ total

includes taxes & fees

1 Oct - 2 Oct

20. Rodeway Inn South San Francisco Airport

South San Francisco

uriel

2.351.614 ₫

2.763.662 ₫ total

includes taxes & fees

27 Sept - 28 Sept

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Where to stay in South San Francisco

Find the best South San Francisco areas for the activities you enjoy most.Learn more about South San Francisco

A panoramic view of San Francisco's South Peninsula, highlighting the city's dense urban areas, rolling hills, and the iconic Golden Gate Bridge in the distance.

An aerial view of a city with a large stadium, several schools, and a dense residential area.

An aerial view of a coastal city with a dense urban area, a large port, and a mountainous backdrop.

Downtown South San Francisco

City centre South San Francisco blends business energy with cultural richness just minutes from San Francisco proper. Modern biotech campuses stand alongside vibrant ethnic markets on Grand Avenue. The area hums with professional activity while celebrating its diverse heritage through colourful murals. This well-connected hub offers excellent transport options via BART and Caltrain stations. Authentic dining reflects the area's Hispanic and Asian communities. After business hours, the atmosphere becomes quietly residential with limited evening entertainment.

See properties

A wooden bridge over a river, surrounded by autumn-colored vegetation and a distant mountain.

A nighttime view of the Golden Gate Bridge with its distinctive orange color and suspension cables.

A modern building complex by a calm river with sparse vegetation.

Oyster Point

Oyster Point blends sleek biotech campuses with refreshing waterfront beauty along San Francisco Bay. Modern glass buildings reflect the calm waters where walking paths invite you to explore. The area showcases contemporary plazas and public art installations throughout the business district. Corporate lunch spots serve the weekday crowd while evening options remain limited. The Bay Trail offers panoramic views and peaceful walks away from the office buzz. Visitors can observe both cutting-edge architecture and natural bay ecosystems during business hours.

See properties

A large, modern bridge with a unique design against a clear blue sky.

The Golden Gate Bridge with its distinctive red towers and cables, spanning across the San Francisco Bay.

The East Side

The East Side of South San Francisco blends cultural diversity with suburban charm just minutes from San Francisco Bay. Hispanic and Asian communities contribute authentic flavours to local eateries along Grand Avenue. Views of San Bruno Mountain create a distinctive backdrop for this working-class area. Visitors can explore Orange Memorial Park's recreational areas or hike nearby mountain trails. Budget-conscious travellers appreciate the area's affordable dining options and practical accommodation. Easy connections to BART and Caltrain make exploring the greater Bay Area convenient without downtown's premium prices.

See properties

A mountainous landscape with rolling hills, dense forests, and a distant view of hills.

Paradise Valley

Paradise Valley offers a quiet retreat from San Francisco's hustle while keeping you connected to the Bay Area. This peaceful residential area boasts wide streets and modest homes where local families live their everyday lives. Travellers appreciate the genuine suburban atmosphere and significantly lower prices than city centre. Just minutes from San Francisco International Airport, Paradise Valley serves as a practical base for exploring the region. Small local parks provide green spaces for relaxation. Though lacking tourist attractions within its boundaries, the neighborhood's proximity to major highways makes Bay Area adventures easily accessible.

See properties

Avalon

Though Avalon may not have many top sights, you can venture to the surrounding area to see attractions like See's Candies and The Shops at Tanforan.

See properties

Stay near popular South San Francisco attractions

San Bruno Point Park

7.8/10 (451 reviews)

Point San Bruno Park offers panoramic views of San Francisco Bay and close-up aircraft sightings from nearby SFO. Stroll the waterfront trails and find a peaceful picnic spot away from the city's bustle.

See properties

South San Francisco Convention Center

7.8/10 (668 reviews)

The South San Francisco Conference Centre offers versatile meeting spaces with modern amenities near SFO airport. Business travellers appreciate its convenient location and comprehensive event services.

See properties

San Francisco Baking Institute

7.6/10 (423 reviews)

Explore the campus of San Francisco Baking Institute as part of your travels around South San Francisco. Amble around this vibrant area's seaside and enjoy its top-notch restaurants.

See properties

See's Candies

8.0/10 (474 reviews)

This American-made chocolate factory store welcomes visitors with the intoxicating aroma of fresh confections. Customise your own box of premium sweets and savour the complimentary sample that greets every guest.

See properties

K1 Speed San Francisco

7.6/10 (330 reviews)

Race electric go-karts at top speeds on K1 Speed's professionally designed indoor track. For the ultimate experience, arrive on weekday afternoons when the track is less crowded.

See properties

South San Francisco Hillside Sign

You can find out about the history of South San Francisco with a visit to South San Francisco Hillside Sign.

See properties

Sign Hill Park

Explore the great outdoors at Sign Hill Park, a lovely green space in South San Francisco. Visit the shops and top-notch restaurants in this family-friendly area.

See properties

Learn more about South San Francisco

Perched on the edge of San Francisco Bay, this family-friendly city boasts a surprising castle and stunning mountain views. Foodies flock to local restaurants, while thrill-seekers race go-karts at K1 Speed or tour the famous See's Sweets factory.

See all hotels in South San Francisco

Top South San Francisco Hotel Reviews

Travelodge by Wyndham San Francisco Airport North

10/10 Excellent

"Gracias a Gabriel por ayudandome con mi reservación del hotel. I extended my stay for a 3rd night and he explained to me that they will give me back my security deposit, which is $100, tomorrow when I check out."

Handlery Union Square Hotel

10/10 Excellent

"Nice location. Clean, quiet and staff is always helpful. So easy to catch transportation nearby also!!"

Hilton San Francisco Union Square

10/10 Excellent

"今回は1人で滞在しました。お部屋は広く清潔で、立地も良く、スタッフの対応も非常に良かったです。 1階のショップには、きちんとしたカットフルーツやサラダ、サンドイッチなども販売されていて、ちょっとした食事を買うのにもとても便利でした。そして、最上階のバーはとにかく絶景です！宿泊するなら、ぜひ一度は行くことをおすすめします。"

Stanford Court San Francisco

10/10 Excellent

"Clean, charming, quiet, convenient, valet parking, great breakfast."

FOUND Hotel Carlton, Nob Hill

8/10 Good

"Extremely helpful staff. Could improve on the coffee experience."

Hilton San Francisco Financial District

8/10 Good

"Fix the elevators !"

Grand Hyatt San Francisco

10/10 Excellent

"The staff were pleasant and helpful, and the room very comfortable. The location is also very good."

More cheap stays in South San Francisco

Park Pointe Hotel

245 S Airport Blvd South San Francisco CA

1.447.107 ₫

1.728.706 ₫ total

5 Sept - 6 Sept

includes taxes & fees

Travelodge by Wyndham San Francisco Airport North

326 S Airport Blvd South San Francisco CA

1.996.267 ₫

2.369.002 ₫ total

9 Sept - 10 Sept

includes taxes & fees

6/10 (4,014 reviews)

FOUND Hotel Carlton, Nob Hill

1075 Sutter St San Francisco CA

2.312.761 ₫

2.722.005 ₫ total

10 Sept - 11 Sept

includes taxes & fees

8.6/10 Excellent! (1,853 reviews)

Good Nite Inn - Redwood City

485 Veterans Blvd Redwood City CA

2.581.326 ₫

2.915.334 ₫ total

6 Sept - 7 Sept

includes taxes & fees

Hotel Aluxor SFO

500 El Camino Real San Bruno CA

2.426.835 ₫

2.933.600 ₫ total

11 Sept - 12 Sept

includes taxes & fees

Comfort Inn by the Bay

2775 Van Ness Ave San Francisco CA

3.443.072 ₫

4.052.323 ₫ total

7 Sept - 8 Sept

includes taxes & fees

8.4/10 Very good! (1,666 reviews)

Hotels in South San Francisco with star rating

Frequently asked questions

What's the weather like in South San Francisco?

The hottest months are usually September and August, with an average temperature of 17°C, while the coldest months are February and January, with an average of 11°C. Average annual precipitation for South San Francisco is 574 mm.

Explore a world of travel with Expedia

More ways to book

Book Hotels in South San Francisco on Expedia.com

Find hotels in South San Francisco, CA from 1.728.706 ₫

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in South San Francisco

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for South San Francisco hotels

1. Best Western Plus Grosvenor Airport Hotel

2. Embassy Suites by Hilton San Francisco Airport Oyster Point

3. La Quinta Inn & Suites by Wyndham San Francisco Airport N

4. DoubleTree by Hilton San Francisco South Airport Blvd

5. Sonesta Select San Francisco Airport Oyster Point Waterfront

6. Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

7. Hotel Nova SFO

8. Home2 Suites by Hilton San Francisco Airport North

9. Hampton Inn San Francisco Airport

10. Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

11. AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

12. Airport Inn

13. Hilton Garden Inn San Francisco Arpt North

14. Hotel Focus SFO

15. Holiday Inn Express San Francisco-Airport North by IHG

16. Comfort Inn and Suites San Francisco Airport North

17. Travelodge by Wyndham San Francisco Airport North

18. Four Points by Sheraton Hotel & Suites San Francisco Airport

19. Inn By The SFO

20. Rodeway Inn South San Francisco Airport

Where to stay in South San Francisco

Downtown South San Francisco

Oyster Point

The East Side

Paradise Valley

Avalon

Stay near popular South San Francisco attractions

San Bruno Point Park

South San Francisco Convention Center

San Francisco Baking Institute

See's Candies

K1 Speed San Francisco

South San Francisco Hillside Sign

Sign Hill Park

Learn more about South San Francisco

Top South San Francisco Hotel Reviews

Travelodge by Wyndham San Francisco Airport North

Handlery Union Square Hotel

Hilton San Francisco Union Square

Stanford Court San Francisco

FOUND Hotel Carlton, Nob Hill

Hilton San Francisco Financial District

Grand Hyatt San Francisco

More cheap stays in South San Francisco

Park Pointe Hotel

Travelodge by Wyndham San Francisco Airport North

FOUND Hotel Carlton, Nob Hill

Good Nite Inn - Redwood City

Hotel Aluxor SFO

Comfort Inn by the Bay

Hotels in South San Francisco with star rating

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app