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Search Adults Only Resorts & Hotels in Southeast Missouri

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Check availability on Southeast Missouri Adults Only Resorts & Hotels

Tonight
4 Dec - 5 Dec
Tomorrow
5 Dec - 6 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Southeast Missouri Adults Only Resorts & Hotels

No exact matches found, but these alternatives could be just right

Recommended hotels in Southeast Missouri

Front of property
Echo Bluff State Park

Echo Bluff State Park

2.5 star property
Eminence
9.6 out of 10, Exceptional, (216)
"Beautiful location…excellent service and facilities / grounds were clean and well kept."
United States
William
The price is 4.193.307 ₫
4.433.374 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Echo Bluff State Park
Exterior
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
Perryville
9.2 out of 10, Wonderful, (536)
"Clean room and pleasant staff"
United States
David
The price is 2.294.451 ₫
2.626.572 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Holiday Inn Express & Suites Perryville by IHG
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1000)
"Clean room, great location and friendly staff"
United States
Mark
The price is 2.373.306 ₫
2.728.550 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Drury Inn & Suites Sikeston, MO
Breakfast, lunch, dinner served; Italian cuisine
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (695)
"Amazing place"
United States
Mladen
The price is 2.616.202 ₫
2.955.654 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Holiday Inn Poplar Bluff by IHG
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1000)
"Great place and staff, very accommodating!"
United States
Megan
The price is 2.373.306 ₫
2.677.123 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (955)
"Delicious, well-ran breakfast and quiet peaceful hotel. "
United States
Janene
The price is 2.716.155 ₫
3.068.762 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Drury Inn & Suites Poplar Bluff
Front of property
The Farmstead Hotel

The Farmstead Hotel

2.5 star property
Caruthersville
8.8 out of 10, Excellent, (460)
"Clean rooms and really comfortable beds!"
United States
Andrea
The price is 2.254.891 ₫
2.564.374 ₫ total
includes taxes & fees
7 Dec - 8 Dec
The Farmstead Hotel
Terrace/patio
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (796)
"Staff was kind and provided a lot of information during check out."
United States
Shea
The price is 2.574.005 ₫
2.882.042 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Poplar Bluff
Lobby lounge
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (846)
"Very clean, great check in"
United States
Teresa
The price is 2.742.792 ₫
3.098.669 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Fairfield Inn & Suites by Marriott Poplar Bluff
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 star property
Sikeston
9.0 out of 10, Wonderful, (437)
"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."
United States
Doncheial
The price is 2.510.710 ₫
2.842.751 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southeast Missouri Hotel Reviews

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