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Top Southeast Missouri Family-Friendly Hotels
Holiday Inn Express & Suites Perryville by IHG
Perryville
9.2 out of 10, Wonderful, (536)
"Clean room and pleasant staff"
David
The price is 2.294.451 ₫
2.626.572 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Drury Inn & Suites Sikeston, MO
Sikeston
9.4 out of 10, Exceptional, (1000)
"Clean room, great location and friendly staff"
Mark
The price is 2.373.306 ₫
2.728.550 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
9.6 out of 10, Exceptional, (1000)
"Great place and staff, very accommodating!"
Megan
The price is 2.373.306 ₫
2.677.123 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Drury Inn & Suites Poplar Bluff
Poplar Bluff
9.2 out of 10, Wonderful, (955)
"Delicious, well-ran breakfast and quiet peaceful hotel.
"
Janene
The price is 2.716.155 ₫
3.068.762 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Hampton Inn By Hilton Dexter
Dexter
10.0 out of 10, Exceptional, (1)
"Staff was helpful and professional. The rooms were clean and comfortable "
Michael
The price is 2.573.477 ₫
2.889.706 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
Pear Tree Inn Cape Girardeau Near the Medical Center
Cape Girardeau
9.0 out of 10, Wonderful, (1003)
"I liked how comfortable the beds and pillows were."
Christine
The price is 1.845.846 ₫
2.082.412 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
9.4 out of 10, Exceptional, (139)
"Nice hotel, clean and comfortable "
Laura
The price is 2.320.824 ₫
2.618.214 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Motel 6 Poplar Bluff, MO
Poplar Bluff
7.8 out of 10, Good, (1002)
"Check in was smooth and facilities are excellent "
Hector
The price is 2.004.348 ₫
2.114.060 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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