Search Spa Hotels in Southern Indiana

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southern Indiana Spa Hotels

Tonight
1 Dec - 2 Dec
Tomorrow
2 Dec - 3 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Southern Indiana Spa Hotels

Exterior
Belterra Casino Resort

Belterra Casino Resort

3.5 star property
Florence
8.6 out of 10, Excellent, (1005)
"Room was clean and the staff was good."
United States
Gary
The price is 2.565.314 ₫
3.197.705 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Belterra Casino Resort
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3832)
"Great place to stay "
United States
Tia
The price is 2.460.119 ₫
2.894.575 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Galt House Hotel Trademark Collection by Wyndham
32-inch Smart TV with cable channels
The Reserve on Main

The Reserve on Main

4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is 3.559.275 ₫
5.449.646 ₫ total
includes taxes & fees
3 Dec - 4 Dec
The Reserve on Main
Indoor pool
Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination

3.5 star property
Elizabeth
8.2 out of 10, Very good, (1021)
"Easy parking, Very friendly/helpful staff, easy check in/out, Nice casino, Good food options"
United States
Leslie
The price is 1.877.188 ₫
2.610.978 ₫ total
includes taxes & fees
2 Dec - 3 Dec
Caesars Southern Indiana - A Caesars Rewards Destination
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1704)
"Wonderful property and staff. Would love to stay again. "
United States
Hanna
The price is 4.408.439 ₫
5.186.970 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Omni Louisville Hotel
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1005)
" Loved our stay, would definitely plan to come back if we are ever in the area again."
United States
Erica
The price is 3.664.735 ₫
4.444.084 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
21c Museum Hotel Louisville
Lobby
Quality Inn Seymour I-65

Quality Inn Seymour I-65

2.5 star property
Seymour
7.0 out of 10, Good, (558)
"Had a room on first floor close to breakfast and desk."
United States
Karlyn
The price is 2.191.722 ₫
2.454.729 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Quality Inn Seymour I-65
Exterior detail
Central Park Bed & Breakfast

Central Park Bed & Breakfast

4.0 star property
Old Louisville
9.4 out of 10, Exceptional, (56)
"The room was beautiful, breakfast was delicious and the park across the street was lovely. I especially enjoyed having coffee on the back veranda."
United States
Cher
The price is 3.574.567 ₫
4.149.060 ₫ total
includes taxes & fees
2 Dec - 3 Dec
Central Park Bed & Breakfast
Bar (on property)
Pillow and Paddock B&B

Pillow and Paddock B&B

3.5 star property
La Grange
10.0 out of 10, Exceptional, (51)
"This has been our second time staying here and we will continue to come back. Beautiful home, amazing breakfasts, and wonderful hosts, not much else we could ask for. "
United States
Rachel
The price is 8.889.408 ₫
9.799.683 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Pillow and Paddock B&B
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southern Indiana Hotel Reviews

Explore a world of travel with Expedia