Find hotels in Defiance, MO from 1.693.685 ₫

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Check prices for these dates

Tonight
21 Jan - 22 Jan
Tomorrow
22 Jan - 23 Jan
This weekend
23 Jan - 25 Jan
Next weekend
30 Jan - 1 Feb

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Our top choices for Defiance hotels

Suite, 1 King Bed, Non Smoking (Upgraded) | In-room safe, laptop workspace, blackout curtains, iron/ironing board

Super 8 by Wyndham St. Clair MO

Super 8 by Wyndham St. Clair MO
2.0 star property
St. Clair
7.2 out of 10, Good, (953 reviews)
"Room was okay, definitely not the best but good for the price. "
United States
Mason
The price is 1.701.907 ₫
1.863.163 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Super 8 by Wyndham St. Clair MO
Lobby

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.2 out of 10, Wonderful, (649 reviews)
"Isa a great place to stay I always enjoy it!"
United States
vicki
The price is 3.388.056 ₫
3.857.302 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Best Western Plus Washington Hotel
Exterior

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (864 reviews)
"Beautiful hotel, friendly staff, good breakfast."
United States
Erika
The price is 3.545.640 ₫
4.224.762 ₫ total
includes taxes & fees
23 Jan - 24 Jan
Holiday Inn Express & Suites Wentzville St Louis West by IHG
Exterior

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,005 reviews)
"Great hotel for the money"
United States
Jere
The price is 2.046.044 ₫
2.351.457 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Comfort Suites St Charles - St Louis
Lobby

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
St. Charles
9.6 out of 10, Exceptional, (1,000 reviews)
"Great hotel "
United States
John Christopher
The price is 3.020.097 ₫
3.500.991 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Drury Plaza Hotel St. Louis St. Charles
Lobby

Quality Inn Near Six Flags St. Louis

Quality Inn Near Six Flags St. Louis
2.5 star property
Pacific
8.4 out of 10, Very good, (365 reviews)
"Excellent staff & very clean room"
United States
Karen
The price is 2.600.136 ₫
2.976.505 ₫ total
includes taxes & fees
29 Jan - 30 Jan
Quality Inn Near Six Flags St. Louis
Lobby

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
St. Charles
8.8 out of 10, Excellent, (1,000 reviews)
"My favorite hotel"
United States
Edward
The price is 3.208.936 ₫
3.687.933 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Embassy Suites by Hilton St. Louis St. Charles
Exterior

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,000 reviews)
"Great room, great amenities!"
United States
Linda or James
The price is 3.424.300 ₫
3.988.897 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Hilton St. Louis Frontenac
Free daily buffet breakfast

Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
St. Charles
9.2 out of 10, Wonderful, (643 reviews)
"The breakfast was delicious and contained a wide variety. The staff friendly and the rooms very clean. "
United States
Kim
The price is 2.982.653 ₫
3.589.024 ₫ total
includes taxes & fees
8 Feb - 9 Feb
Hampton Inn & Suites St. Charles Old Town Area
Lobby lounge

Fairfield Inn & Suites Wentzville

Fairfield Inn & Suites Wentzville
2.5 star property
Wentzville
9.0 out of 10, Wonderful, (649 reviews)
"Hotel staff was friendly and room was very clean "
United States
Danielle
The price is 3.358.640 ₫
3.843.963 ₫ total
includes taxes & fees
27 Jan - 28 Jan
Fairfield Inn & Suites Wentzville
Room, 2 Queen Beds, Non Smoking | In-room safe, desk, blackout curtains, iron/ironing board

Super 8 by Wyndham Washington

Super 8 by Wyndham Washington
2.0 star property
Washington
8.4 out of 10, Very good, (705 reviews)
"The staff was extremely nice & accommodating."
United States
Brenda
The price is 2.220.621 ₫
2.528.177 ₫ total
includes taxes & fees
29 Jan - 30 Jan
Super 8 by Wyndham Washington
Lobby sitting area

Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
St. Charles
8.2 out of 10, Very good, (1,005 reviews)
"Very nice at service desk, room clean and comfortable, breakfast really good. Would recommend, would stay again!"
United States
Melisa
The price is 2.321.738 ₫
2.691.520 ₫ total
includes taxes & fees
26 Jan - 27 Jan
Best Western Plus The Charles Hotel
Exterior

Holiday Inn Express & Suites St Peters by IHG

Holiday Inn Express & Suites St Peters by IHG
2.5 star property
St. Peters
9.2 out of 10, Wonderful, (383 reviews)
"Parking was easy and the room was nice."
United States
Martha
The price is 2.652.664 ₫
3.207.084 ₫ total
includes taxes & fees
29 Jan - 30 Jan
Holiday Inn Express & Suites St Peters by IHG
Exterior

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
9.4 out of 10, Exceptional, (34 reviews)
"Super clean , quiet place "
United States
Phoenix
The price is 2.337.496 ₫
2.767.438 ₫ total
includes taxes & fees
29 Jan - 30 Jan
WoodSpring Suites St Peters-OFallon
Exterior

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1,001 reviews)
"We had a great stay in a beautiful area. The staff were friendly, and Kay at the front desk was so kind and welcoming!"
United States
Audrey
The price is 3.094.017 ₫
3.555.860 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Country Inn & Suites by Radisson, St. Charles Historic District
Lobby

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (923 reviews)
"Clean rooms, pleasant staff."
United States
Karen
The price is 1.942.223 ₫
2.193.742 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Quality Inn Foristell
Family Studio Suite (No Elevator Access) | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds

River Sirens Hotel

River Sirens Hotel
2.5 star property
Washington
9.8 out of 10, Exceptional, (186 reviews)
"Great place"
United States
Herchel
River Sirens Hotel
Lobby

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.4 out of 10, Exceptional, (1,002 reviews)
"Awesome staff "
United States
John
The price is 2.888.777 ₫
3.320.820 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Drury Inn & Suites St. Louis St. Peters
Lobby

Days Inn by Wyndham St Peters/St Charles

Days Inn by Wyndham St Peters/St Charles
2.0 star property
St. Peters
6.2 out of 10, (1,000 reviews)
"Room was excellent and clean"
United States
catherine
The price is 1.473.410 ₫
1.693.685 ₫ total
includes taxes & fees
18 Feb - 19 Feb
Days Inn by Wyndham St Peters/St Charles
Reception

Hampton Inn St. Louis Wentzville

Hampton Inn St. Louis Wentzville
2.5 star property
Wentzville
9.0 out of 10, Wonderful, (645 reviews)
"Easy check in accessible room, comfortable bed and chairs"
United States
Maurine
The price is 3.190.025 ₫
3.650.982 ₫ total
includes taxes & fees
30 Jan - 31 Jan
Hampton Inn St. Louis Wentzville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Missouri wineries have some of the most superb wine we've ever tasted! We recommend sipping on some chambourcin while basking in the sunshine.
Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
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Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri

August A. Busch Memorial Conservation Area

This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

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A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

10/10 Excellent
"Room was nice and clean. Spacious suite."
James 1-night trip
Posted 7 days ago
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

More cheap stays in Defiance

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

1310 Bass Pro Drive St. Charles MO
The price is 1.562.445 ₫ per night from 1 Feb to 2 Feb
1.562.445 ₫
1.811.294 ₫ total
1 Feb - 2 Feb
includes taxes & fees
5.6/10 (1,004 reviews)

Hotels in Defiance with star rating

Frequently asked questions

What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.