
Find hotels in Defiance, MO from 1.883.646 ₫
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Our top choices for Defiance hotels

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by WyndhamFenton
8.0 out of 10, Very good, (1,117 reviews)
The price is 2.337.368 ₫
2.699.562 ₫ total
includes taxes & fees
8 Mar - 9 Mar

Quality Inn Foristell
Quality Inn ForistellForistell
8.2 out of 10, Very good, (947 reviews)
The price is 1.782.552 ₫
2.013.393 ₫ total
includes taxes & fees
22 Mar - 23 Mar

Baymont by Wyndham Warrenton
Baymont by Wyndham WarrentonWarrenton
7.4 out of 10, Good, (1,002 reviews)
The price is 1.939.836 ₫
2.215.778 ₫ total
includes taxes & fees
9 Mar - 10 Mar

Wingate by Wyndham St. Louis/Fenton Route 66
Wingate by Wyndham St. Louis/Fenton Route 66Fenton
8.0 out of 10, Very good, (1,152 reviews)
The price is 2.072.217 ₫
2.393.161 ₫ total
includes taxes & fees
8 Mar - 9 Mar

WoodSpring Suites St Peters-OFallon
WoodSpring Suites St Peters-OFallonSt. Peters
9.0 out of 10, Wonderful, (48 reviews)
The price is 2.330.821 ₫
2.759.656 ₫ total
includes taxes & fees
13 Mar - 14 Mar

Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
9.0 out of 10, Wonderful, (1,009 reviews)
The price is 2.074.169 ₫
2.446.482 ₫ total
includes taxes & fees
15 Mar - 16 Mar

Best Western Plus Fenton
Best Western Plus FentonFenton
9.2 out of 10, Wonderful, (222 reviews)
The price is 2.390.717 ₫
2.760.992 ₫ total
includes taxes & fees
8 Mar - 9 Mar

Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St LouisSt. Charles
8.4 out of 10, Very good, (1,004 reviews)
The price is 2.283.764 ₫
2.624.662 ₫ total
includes taxes & fees
15 Mar - 16 Mar

Best Western Plus Washington Hotel
Best Western Plus Washington HotelWashington
9.2 out of 10, Wonderful, (663 reviews)
The price is 3.378.381 ₫
3.846.287 ₫ total
includes taxes & fees
5 Apr - 6 Apr

Super 8 by Wyndham St Charles
Super 8 by Wyndham St CharlesSt. Charles
8.0 out of 10, Very good, (1,003 reviews)
The price is 2.094.761 ₫
2.407.445 ₫ total
includes taxes & fees
15 Mar - 16 Mar

Quality Inn Near Six Flags St. Louis
Quality Inn Near Six Flags St. LouisPacific
8.4 out of 10, Very good, (366 reviews)
The price is 2.592.711 ₫
2.968.006 ₫ total
includes taxes & fees
10 Mar - 11 Mar

Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. PetersSt. Peters
9.4 out of 10, Exceptional, (1,003 reviews)
The price is 2.883.278 ₫
3.314.326 ₫ total
includes taxes & fees
15 Mar - 16 Mar

Hampton Inn St. Louis Wentzville
Hampton Inn St. Louis WentzvilleWentzville
9.0 out of 10, Wonderful, (666 reviews)
The price is 3.121.729 ₫
3.572.819 ₫ total
includes taxes & fees
15 Mar - 16 Mar

Holiday Inn Express & Suites Wentzville St Louis West by IHG
Holiday Inn Express & Suites Wentzville St Louis West by IHGWentzville
9.4 out of 10, Exceptional, (874 reviews)
The price is 3.475.976 ₫
4.144.084 ₫ total
includes taxes & fees
8 Mar - 9 Mar

Holiday Inn St. Louis West Six Flags by IHG
Holiday Inn St. Louis West Six Flags by IHGEureka
9.0 out of 10, Wonderful, (1,000 reviews)
The price is 3.040.824 ₫
3.542.195 ₫ total
includes taxes & fees
10 Mar - 11 Mar

Fairfield Inn & Suites Wentzville
Fairfield Inn & Suites WentzvilleWentzville
9.0 out of 10, Wonderful, (659 reviews)
The price is 3.352.246 ₫
3.836.647 ₫ total
includes taxes & fees
12 Mar - 13 Mar

Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. PetersSt. Charles
8.0 out of 10, Very good, (1,003 reviews)
The price is 2.643.944 ₫
3.038.605 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

Top Defiance Hotel Reviews

Drury Plaza Hotel St. Louis Chesterfield
8/10 Good
More cheap stays in Defiance

Relax Inn Saint Charles
3800 Harry S Truman Blvd St. Charles MO
The price is 1.649.907 ₫ per night from 6 Apr to 7 Apr
1.649.907 ₫
1.896.084 ₫ total
6 Apr - 7 Apr
includes taxes & fees
6.8/10 (1,004 reviews)
Hotels in Defiance with star rating

4 Star Hotels
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