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Search Luxury Hotels in Cape Girardeau

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Check availability on Cape Girardeau Luxury Hotels

Tonight
27 Nov - 28 Nov
Tomorrow
28 Nov - 29 Nov
This weekend
28 Nov - 30 Nov
Next weekend
5 Dec - 7 Dec

Top Cape Girardeau Luxury Hotels

Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1004)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is 1.845.706 ₫
2.082.254 ₫ total
includes taxes & fees
2 Dec - 3 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center
Lobby
Quality Inn

Quality Inn

2.5 star property
Cape Girardeau
7.2 out of 10, Good, (677)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
The price is 1.518.970 ₫
1.713.611 ₫ total
includes taxes & fees
4 Dec - 5 Dec
Quality Inn
Business centre
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1005)
"Rooms are nice and big. Breakfast was above average and staff was very nice and friendly. "
United States
Sandra
The price is 2.373.126 ₫
2.676.920 ₫ total
includes taxes & fees
2 Dec - 3 Dec
Drury Inn & Suites Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

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Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Cape Girardeau?
Use Expedia to arrange your flight to Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport or Cairo, IL (CIR-Cairo Regional) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a holiday, so we make it easy to get what you want to make your stay relaxing and comfortable. If you want an upscale hotel that has fine dining, a spa or several swimming pools, Expedia can help you find the best luxury hotel experience that Cape Girardeau has to offer. During your visit, you might want to enjoy the university which Cape Girardeau is known for.
When can I expect good weather in Cape Girardeau?
Planning for the weather is an important factor for making your trip to Cape Girardeau a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Cape Girardeau is 1495 mm.
What's there to see and do in Cape Girardeau?
Enjoy all that Cape Girardeau has to offer and visit Isle Casino Cape Girardeau, Show Me Center and Cape Splash Family Aquatic Center. If you have a bit of extra time while you're in the area, you might want to check out Trail of Tears State Park and Shawnee National Forest.