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Check availability on St. Louis Luxury Hotels

Our top choices for St. Louis luxury hotels

Terrace/patio
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1002)
"Everything exceeded my expectations from the welcoming staff to the luxuriously appointed room, to the 4 feet deep bathtub in which to soak my cares away--it was a total dream come true. I would come back in a heartbeat at this home away from home. "
United States
Lynne
The price is 10.917.405 ₫
12.765.613 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Four Seasons Hotel St Louis
Meeting facility
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (553)
"Service is exceptional!!!"
United States
Jorge
The price is 13.127.193 ₫
15.324.354 ₫ total
includes taxes & fees
21 Dec - 22 Dec
The Ritz-Carlton, St. Louis
Seasonal outdoor pool
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very good, (1004)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is 4.002.610 ₫
5.114.081 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Ameristar Casino Resort and Spa
Breakfast, lunch and dinner served
Live by Loews - St.Louis

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1097)
"Great staff"
United States
Phillip
The price is 3.919.743 ₫
4.661.710 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Live by Loews - St.Louis
Property amenity
Moonrise Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1915)
"Great service, unique hotel. Would absolutely stay again!"
United States
Michael
The price is 2.963.679 ₫
3.524.672 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Moonrise Hotel
Seasonal outdoor pool
The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.0 out of 10, Wonderful, (1001)
"Always, a great time and place to stay."
United States
Lubna
The price is 4.182.813 ₫
5.708.279 ₫ total
includes taxes & fees
23 Dec - 24 Dec
The Royal Sonesta Chase Park Plaza St. Louis
Exterior
Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1001)
"Clean room, felt like a mini apartment! The surrounding was beautiful. "
United States
Jane
The price is 3.429.907 ₫
3.995.430 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton St. Louis Frontenac
Rooftop bar
Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (467)
"Everything was definitely worth the stay! "
United States
Briana
The price is 4.077.585 ₫
4.849.431 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hotel Saint Louis, Autograph Collection
Restaurant
21C Museum Hotel St Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1499)
"Room was perfect and parking was a breeze. We really enjoyed the art was wonderful. "
United States
London
The price is 3.527.769 ₫
4.256.520 ₫ total
includes taxes & fees
21 Dec - 22 Dec
21C Museum Hotel St Louis
Reception
DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
4.0 star property
Chesterfield
8.6 out of 10, Excellent, (1000)
"Great hotel!"
United States
John
The price is 3.331.782 ₫
3.864.467 ₫ total
includes taxes & fees
27 Dec - 28 Dec
DoubleTree by Hilton Hotel St. Louis - Chesterfield
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Louis Hotel Reviews

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Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in St. Louis?
Travel to Lambert-St. Louis International Airport (STL) Airport or St. Louis, MO (SUS-Spirit of St. Louis) Airport, and then treat yourself to a stay at one of 7 St. Louis luxury hotels. Known for its art and theatre, St. Louis also has some interesting things to see and do including St. Louis Union Station and Gateway Arch, so you may want to take in the local sights during your visit.
How many luxury hotels will I find in St. Louis?
Lie in the lap of luxury during your getaway to St. Louis in one of Expedia's 7 luxury hotels.
When can I expect good weather in St. Louis?
Planning for the weather is a good way to make your trip to St. Louis relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Louis is 1374 mm.
What's there to see and do in St. Louis?
Take in some sights and attractions while you're in St. Louis by visiting St. Louis Union Station, Gateway Arch and St. Louis Aquarium at Union Station. If you have extra time while you're in the area, you might want to see St. Louis Union Station Mini Golf and The St. Louis Wheel.
How can I get around St. Louis?
It's easier to get around town comfortably when you know your options. Take advantage of metro transport at Stadium Station, 8th and Pine Station and Convention Center Station.