Compare and book 4 Star hotels in Serra Mesa, San Diego

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Check availability on Serra Mesa 4 Star Hotels

Top Serra Mesa 4 Star Hotels

Manchester Grand Hyatt San Diego
6 restaurants, breakfast, lunch, dinner served; seafood

Manchester Grand Hyatt San Diego

4.0 star property
9.0 out of 10, Wonderful, (2796)
"We had a great stay here. "
The price is 4.468.867 ₫
6.610.624 ₫ total
includes taxes & fees
31 Aug - 1 Sept
Manchester Grand Hyatt San Diego
Hyatt Regency Mission Bay Spa and Marina
Exterior

Hyatt Regency Mission Bay Spa and Marina

4.0 star property
8.4 out of 10, Very good, (1506)
"Its a great hotel "
The price is 4.232.419 ₫
6.161.215 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Hyatt Regency Mission Bay Spa and Marina
Wyndham San Diego Bayside
Terrace/patio

Wyndham San Diego Bayside

4.0 star property
8.4 out of 10, Very good, (5864)
"Great location great price. "
The price is 3.997.285 ₫
5.283.658 ₫ total
includes taxes & fees
3 Sept - 4 Sept
Wyndham San Diego Bayside
Embassy Suites by Hilton San Diego Bay Downtown
Lobby

Embassy Suites by Hilton San Diego Bay Downtown

4.0 star property
9.0 out of 10, Wonderful, (1368)
"Great location and breakfast, would stay here again."
The price is 4.890.533 ₫
6.410.936 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Embassy Suites by Hilton San Diego Bay Downtown
Sheraton Mission Valley San Diego Hotel
Outdoor pool

Sheraton Mission Valley San Diego Hotel

4.0 star property
8.6 out of 10, Excellent, (1503)
"Very nice stay. Will definitely stay here anytime I come back to SD. "
The price is 3.336.544 ₫
3.835.191 ₫ total
includes taxes & fees
25 Aug - 26 Aug
Sheraton Mission Valley San Diego Hotel
Paradise Point Resort & Spa
Property grounds

Paradise Point Resort & Spa

4.0 star property
8.6 out of 10, Excellent, (2231)
"Its amazing place for vacation "
The price is 4.783.343 ₫
6.828.102 ₫ total
includes taxes & fees
25 Aug - 26 Aug
Paradise Point Resort & Spa
Sheraton San Diego Resort
Room, 1 King Bed with Sofa bed, Marina View | View from room

Sheraton San Diego Resort

4.0 star property
8.2 out of 10, Very good, (2932)
"Excellent stay.. "
The price is 3.336.544 ₫
4.922.325 ₫ total
includes taxes & fees
31 Aug - 1 Sept
Sheraton San Diego Resort
San Diego Marriott La Jolla
Outdoor pool

San Diego Marriott La Jolla

4.0 star property
8.6 out of 10, Excellent, (1998)
"Enjoyed my stay."
The price is 4.933.356 ₫
5.674.162 ₫ total
includes taxes & fees
1 Sept - 2 Sept
San Diego Marriott La Jolla
DoubleTree by Hilton San Diego - Del Mar
Courtyard

DoubleTree by Hilton San Diego - Del Mar

4.0 star property
8.0 out of 10, Very good, (1427)
"Great stay."
The price is 3.215.693 ₫
3.664.121 ₫ total
includes taxes & fees
24 Aug - 25 Aug
DoubleTree by Hilton San Diego - Del Mar
The Little Italy Hotel Downtown San Diego
View from room

The Little Italy Hotel Downtown San Diego

4.0 star property
8.0 out of 10, Very good, (1029)
"Great stay"
The price is 3.100.096 ₫
3.588.360 ₫ total
includes taxes & fees
1 Sept - 2 Sept
The Little Italy Hotel Downtown San Diego
Hilton San Diego Bayfront
Outdoor pool, pool loungers

Hilton San Diego Bayfront

4.0 star property
8.4 out of 10, Very good, (1673)
"Beautiful stay!"
The price is 4.716.875 ₫
6.734.238 ₫ total
includes taxes & fees
31 Aug - 1 Sept
Hilton San Diego Bayfront
Marriott Marquis San Diego Marina
2 outdoor pools, open 6 AM to 10:00 PM, pool cabanas (surcharge)

Marriott Marquis San Diego Marina

4.0 star property
9.2 out of 10, Wonderful, (1822)
"Great place to stay."
The price is 5.727.296 ₫
7.813.949 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Marriott Marquis San Diego Marina
Hard Rock Hotel San Diego
Outdoor pool

Hard Rock Hotel San Diego

4.0 star property
9.0 out of 10, Wonderful, (2811)
"Always an enjoyable stay"
The price is 4.710.044 ₫
6.668.269 ₫ total
includes taxes & fees
12 Sept - 13 Sept
Hard Rock Hotel San Diego
Embassy Suites by Hilton San Diego La Jolla
Terrace/patio

Embassy Suites by Hilton San Diego La Jolla

4.0 star property
8.8 out of 10, Excellent, (1629)
"Great accommodations. "
The price is 4.512.216 ₫
5.186.566 ₫ total
includes taxes & fees
28 Aug - 29 Aug
Embassy Suites by Hilton San Diego La Jolla
Hotel del Coronado, Curio Collection by Hilton
Lobby

Hotel del Coronado, Curio Collection by Hilton

4.0 star property
8.0 out of 10, Very good, (1007)
"Family friendly. Loved our stay. "
The price is 7.901.304 ₫
10.230.647 ₫ total
includes taxes & fees
7 Sept - 8 Sept
Hotel del Coronado, Curio Collection by Hilton
Loews Coronado Bay Resort
Exterior

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1014)
"Loved our stay very accommodating "
The price is 5.228.128 ₫
6.998.861 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Loews Coronado Bay Resort
Palihotel San Diego Gaslamp Quarter
Rooftop terrace

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.8 out of 10, Excellent, (1636)
"Enjoyed the stay !! "
The price is 2.758.560 ₫
3.193.099 ₫ total
includes taxes & fees
27 Aug - 28 Aug
Palihotel San Diego Gaslamp Quarter
Legacy Resort Hotel & Spa
Garden

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2865)
"Great stay"
The price is 4.029.599 ₫
4.632.016 ₫ total
includes taxes & fees
5 Sept - 6 Sept
Legacy Resort Hotel & Spa
Town and Country San Diego
2 outdoor pools, a heated pool, pool cabanas (surcharge), pool loungers

Town and Country San Diego

4.0 star property
8.6 out of 10, Excellent, (1257)
"this is really nice family hotel"
The price is 5.887.555 ₫
7.674.051 ₫ total
includes taxes & fees
23 Aug - 24 Aug
Town and Country San Diego
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
Terrace/patio

The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott

4.0 star property
9.0 out of 10, Wonderful, (1010)
"Nice places to stay "
The price is 3.651.808 ₫
4.226.968 ₫ total
includes taxes & fees
1 Sept - 2 Sept
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Serra Mesa.
Pendry San Diego

Pendry San Diego

550 J Street, San Diego, CA
The price is 6.568.000 ₫ per night from 31 Aug to 1 Sept
6.568.000 ₫
8.936.027 ₫ total
31 Aug - 1 Sept
includes taxes & fees
9.2/10 Wonderful! (1,006 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Serra Mesa?
Enjoy the quality and comfort of San Diego Marriott Mission Valley. This 4-star hotel around Serra Mesa is highly recommended by many Expedia guests and comes with concierge services and a terrace. Another sought-after choice in or near this neighbourhood is DoubleTree by Hilton Hotel San Diego - Mission Valley. Premium bedding and designer toiletries help make it popular.
How much does it cost to stay in a 4-star hotel in Serra Mesa?
Expedia can help you quickly locate the ideal 4-star hotel for your stay in Serra Mesa. Use our filter tool to tailor your search by things like price, amenities and hotel star rating and get access to awesome deals in a few clicks.

  • Search for the lowest price from 6.568.000 ₫

What's the difference between 5-star and 4-star hotels in Serra Mesa?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Serra Mesa holiday. These kinds of stays generally feature lots of useful amenities that make it a breeze to unpack and relax — think 24-hour room service, restaurants and pools. Or enjoy even more lavishness at a 5-star hotel designed to pamper with exclusive perks and amenities. Concierge assistance, premium toiletries and gourmet dining are typically featured at these deluxe properties.