Compare and book 5 Star hotels in Lake Nona Medical City, Orlando

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Check availability on Lake Nona Medical City 5 Star Hotels

Tonight
27 Jun - 28 Jun
Tomorrow
28 Jun - 29 Jun
This weekend
27 Jun - 29 Jun
Next weekend
4 Jul - 6 Jul

Top Lake Nona Medical City 5 Star Hotels

Waldorf Astoria Orlando - An Official Walt Disney World® Hotel
Exterior

Waldorf Astoria Orlando - An Official Walt Disney World® Hotel

5.0 star property
9.2 out of 10, Wonderful, (282)
"Excellent service and food "
The price is 7.501.664 ₫
9.908.622 ₫ total
includes taxes & fees
11 Jul - 12 Jul
Waldorf Astoria Orlando - An Official Walt Disney World® Hotel
Conrad Orlando at Evermore
Outdoor pool, pool cabanas (surcharge), pool umbrellas

Conrad Orlando at Evermore

5.0 star property
9.4 out of 10, Exceptional, (223)
"The lagoon was perfect"
The price is 11.179.360 ₫
13.882.780 ₫ total
includes taxes & fees
14 Jul - 15 Jul
Conrad Orlando at Evermore
The Ritz-Carlton Orlando, Grande Lakes
Property amenity

The Ritz-Carlton Orlando, Grande Lakes

5.0 star property
9.2 out of 10, Wonderful, (1005)
"Well maintained, high-end property and friendly staff. "
The price is 10.683.080 ₫
13.634.772 ₫ total
includes taxes & fees
29 Jun - 30 Jun
The Ritz-Carlton Orlando, Grande Lakes
Four Seasons Resort Orlando at WALT DISNEY WORLD® Resort
3 outdoor pools, pool cabanas (surcharge), pool umbrellas

Four Seasons Resort Orlando at WALT DISNEY WORLD® Resort

5.0 star property
9.6 out of 10, Exceptional, (851)
"Great stay highly recommended "
The price is 26.018.255 ₫
30.741.418 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Four Seasons Resort Orlando at WALT DISNEY WORLD® Resort
Reunion Resort & Golf Club
Water park

Reunion Resort & Golf Club

5.0 star property
8.6 out of 10, Excellent, (1313)
"We had a fantastic time, enjoyed our stay and will definitely go back again"
The price is 5.472.986 ₫
7.451.301 ₫ total
includes taxes & fees
29 Jun - 30 Jun
Reunion Resort & Golf Club
ette hotel
Outdoor pool, open 9:00 AM to 6:00 PM, free pool cabanas, pool umbrellas

ette hotel

5.0 star property
9.8 out of 10, Exceptional, (310)
"great hotel and very friendly staff very clean rooms and fast service "
ette hotel
Encore Resort and Water Park At Reunion by Rentyl
Outdoor pool, a heated pool, pool cabanas (surcharge), pool umbrellas

Encore Resort and Water Park At Reunion by Rentyl

5.0 star property
8.4 out of 10, Very good, (1002)
"Can’t wait to come back, our family loved our stay, close enough to all the major parks, plazas and airport and then a touch of home when you get back and relax with the privacy of the yard "
Encore Resort and Water Park At Reunion by Rentyl
Splendid 5Bd Close to Disney at Storey Lake 4251
Water park

Splendid 5Bd Close to Disney at Storey Lake 4251

5.0 star property
9.0 out of 10, Wonderful, (10)
"Amazing Stay...Home away from Home... Definitely recommend for families..."
Splendid 5Bd Close to Disney at Storey Lake 4251
Marvelous 5Bd w/ Pool Close to Disney @ Storey Lake 2629
Exclusive House | Private pool

Marvelous 5Bd w/ Pool Close to Disney @ Storey Lake 2629

5.0 star property
8.8 out of 10, Excellent, (3)
"Nice "
Marvelous 5Bd w/ Pool Close to Disney @ Storey Lake 2629
2 Bedroom l Waterpark & Resort Amenities Included, Themed Rooms
Outdoor pool

2 Bedroom l Waterpark & Resort Amenities Included, Themed Rooms

5.0 star property
8.0 out of 10, Very good, (13)
"The kids really enjoyed it and everyone was comfortable, no complaints."
2 Bedroom l Waterpark & Resort Amenities Included, Themed Rooms
Family Vacation Home, Water Park+Endless Amenities
Water park

Family Vacation Home, Water Park+Endless Amenities

5.0 star property
8.2 out of 10, Very good, (20)
"Property is very well kept and close to attractions. Nick, the property manager is very attentive and responds immediately"
Family Vacation Home, Water Park+Endless Amenities
Reunion Resort & Golf Club
10 outdoor pools, pool umbrellas, pool loungers

Reunion Resort & Golf Club

5.0 star property
8.8 out of 10, Excellent, (12)
"Enjoy the accommodations view was wonderful and close to everything"
Reunion Resort & Golf Club
Family Friendly Four Bedroom w GameRoom @Disney 5145
Exclusive House | In-room safe, individually decorated, individually furnished, desk

Family Friendly Four Bedroom w GameRoom @Disney 5145

5.0 star property
8.4 out of 10, Very good, (5)
"It was fantastic!"
Family Friendly Four Bedroom w GameRoom @Disney 5145
Stunning 4 Bd Close to Disney @ Storey Lake 2569
Water park

Stunning 4 Bd Close to Disney @ Storey Lake 2569

5.0 star property
10.0 out of 10, Exceptional, (2)
Stunning 4 Bd Close to Disney @ Storey Lake 2569
Gorgeous 4 Bedroom w/ Pool Close to Disney 920
Exclusive House | 5 bedrooms, in-room safe, individually decorated, individually furnished

Gorgeous 4 Bedroom w/ Pool Close to Disney 920

5.0 star property
Gorgeous 4 Bedroom w/ Pool Close to Disney 920
Gorgeous 4 Bedroom w/ Pool Close to Disney 4836
Townhome, 4 Bedrooms | Private pool

Gorgeous 4 Bedroom w/ Pool Close to Disney 4836

5.0 star property
9.4 out of 10, Exceptional, (10)
"Super clean and confortable. "
Gorgeous 4 Bedroom w/ Pool Close to Disney 4836
Stunning 2 Bd Condo Close to Disney 304 3191
Exterior

Stunning 2 Bd Condo Close to Disney 304 3191

5.0 star property
6.6 out of 10, (4)
"The Place Awesome it was a family trip we had great time my 2 kids love the Pool, the Lazy river. they love the hold place. places are not far from Condo. Great communication they always was checking if we needed anything it was great. Thank You "
Stunning 2 Bd Condo Close to Disney 304 3191
Luxury 8Bd with Pool @ Sonoma Resort 2639
Outdoor pool, a heated pool, pool loungers, lifeguards on site

Luxury 8Bd with Pool @ Sonoma Resort 2639

5.0 star property
2.0 out of 10, (1)
"The property had 8 bedrooms, only 2 were king size. All the beds are so low to the ground. The refrigerator was broken. The coffee table was broken. They charge a massive deposit. Then they send you an email after check out that they deducted money from your deposit and say that you have things damaged. I called the first day to tell them the defects and no one response. I wonder never recommend this place. "
Luxury 8Bd with Pool @ Sonoma Resort 2639
7 Bedroom Villa, Private Pool, Resort Amenities
Luxury Villa, Multiple Bedrooms, Private Pool | Courtyard view

7 Bedroom Villa, Private Pool, Resort Amenities

5.0 star property
9.0 out of 10, Wonderful, (11)
"The house was beautiful. Most of the upstairs televisions did not work but overall it was great would recommend it to friends and family "
7 Bedroom Villa, Private Pool, Resort Amenities
Marvelous 4Bd with Pool at Storey Lake Resort 2601
Water park

Marvelous 4Bd with Pool at Storey Lake Resort 2601

5.0 star property
10.0 out of 10, Exceptional, (2)
Marvelous 4Bd with Pool at Storey Lake Resort 2601
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lake Nona Medical City.
Hyatt Regency Orlando International Airport

Hyatt Regency Orlando International Airport

9300 Jeff Fuqua Boulevard, Orlando, FL
The price is 5.197.880 ₫ per night from 8 Jul to 9 Jul
5.197.880 ₫
5.847.746 ₫ total
8 Jul - 9 Jul
includes taxes & fees
9.4/10 Exceptional! (3,314 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Lake Nona Medical City?
There are several pricing options for a 5-star hotel in Lake Nona Medical City on Expedia. The amount you pay will depend on your holiday dates, length of stay and other factors. Compare all of the available accommodation for your preferred dates and make use of our pricing and other filters to lock in the perfect luxury stay.

  • Search for the lowest price per night from 2.197.998 ₫

What makes a hotel 5 stars in Lake Nona Medical City?
In Lake Nona Medical City, a hotel must provide a certain amount of high-end amenities to be designated 5 stars. These may include saunas and spas, on-site gyms, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding standard of service. You can look forward to things like nightly turn-down services, concierge services and in-room massages. Some may also offer extra touches such as welcome gifts.
Are there any 5-star all-inclusive resorts in Lake Nona Medical City?
Our handy filters are the best way to narrow down what you want. Select "All inclusive" and "5-star" to show the finest hotels in Lake Nona Medical City where your room, meals, entertainment and activities are included in the price. At these getaways, your trip is pure indulgence from the moment you step foot in the lobby.