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Compare and book 5 Star hotels in Medical Center District, San Antonio

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Check availability on Medical Center District 5 Star Hotels

Tonight
4 Jul - 5 Jul
Tomorrow
5 Jul - 6 Jul
This weekend
4 Jul - 6 Jul
Next weekend
11 Jul - 13 Jul

Top Medical Center District 5 Star Hotels

Thompson San Antonio - Riverwalk, by Hyatt
Outdoor pool, open 7:00 AM to 10:00 PM, pool cabanas (surcharge)

Thompson San Antonio - Riverwalk, by Hyatt

5.0 star property
9.0 out of 10, Wonderful, (771)
"It was Amazing! Classy clean and great hospitality! Best place yet and I will definitely book at the Thompson in the future! "
The price is 5.540.997 ₫
7.442.296 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Thompson San Antonio - Riverwalk, by Hyatt
The Luxury Suites at Arrive Eilan
Terrace/patio

The Luxury Suites at Arrive Eilan

5.0 star property
7.4 out of 10, Good, (129)
"Very nice. Easy and Clean"
The Luxury Suites at Arrive Eilan
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Medical Center District.
Riverwalk Plaza

Riverwalk Plaza

100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
The price is 2.282.896 ₫ per night from 28 Jul to 29 Jul
2.282.896 ₫
2.698.588 ₫ total
28 Jul - 29 Jul
includes taxes & fees
8/10 Very Good! (5,440 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Medical Centre District?
The amount you pay for a 5-star hotel in Medical Centre District can vary based on when you decide to travel and how long you plan to stay, among other factors. Use our price per night filter and other search tools to find the best rate on a high-end getaway.

  • Search for the lowest price per night from 2.282.896 ₫

What makes a hotel 5 stars in Medical Centre District?
Exemplary guest service is at the heart of every 5-star hotel in Medical Centre District. From the minute you step through the door, staff cater to your every whim, whether arranging valet parking or providing a turn-down service. On top of that, hotels have to feature upscale amenities to meet the standard for a 5-star rating. These can include luxury bathrooms, spa facilities, pools, fine dining restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Medical Centre District?
Our convenient filters are the quickest way to narrow down what you want. Check the "All inclusive" and "5-star" boxes to see the most luxurious properties in Medical Centre District where your meals, accommodation, activities and entertainment are included in the upfront price. At these stays, your holiday is pure indulgence from the moment you pull up to the entrance.