Medical Center District Travel Guide
San Antonio
Visit Medical Center District
Popular places to visit
South Texas Medical Center
If South Texas Medical Center is what brings you to town, hopefully you'll have a chance to explore more of San Antonio.
River Walk
River Walk is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the fascinating museums and shops in this walkable area.
Lackland Air Force Base
Lackland Air Force Base is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the entertainment venues and shops in this walkable area.
Six Flags Fiesta Texas
Enjoy the excitement at Six Flags Fiesta Texas and see why people love this theme park in San Antonio. Experience the lively festivals and acclaimed theatre scene in this family-friendly area.
San Antonio SeaWorld
Make time to visit the sea life at San Antonio SeaWorld, and find out why this is a popular attraction in San Antonio. Amble around this family-friendly area's seaside or experience its lively festivals.
San Antonio Zoo and Aquarium
Why not visit the animals who live at San Antonio Zoo and Aquarium and see why this is a favourite sight in San Antonio? Experience the great live music and lively festivals in this walkable area.
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Nice and friendly staff! Room was very clean and I had no issues whatsoever. I will definitely be booking here for future stays
Reviewed on 1 Mar 2026
San Antonio Marriott Northwest Medical Center
Everything was great!! Went for my birthday and it was so fun :) wish I had a chance to check out the pool but I was pretty tired 😴
Reviewed on 1 Mar 2026
Park Inn by Radisson
Nothing out of the ordinary but in a good way.
Reviewed on 28 Feb 2026
Crockett Hotel
Staff was friendly and helpful. Hotel and my room were clean. Excellent location to everywhere.
Reviewed on 2 Mar 2026
Hotel Valencia Riverwalk
Arrived and after 1 hr following check in was able to get keys to room. Went upstairs and the room was the basic king, not the deluxe king with balcony that we’d paid for. At no time when we first arrived or when we were given our keys were we told the room was not what we’d reserved. After calling ...
Reviewed on 2 Mar 2026
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Everything was good
Reviewed on 1 Mar 2026
Check Medical Center District hotel availability
Other neighbourhoods around Medical Center District
Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Dub Farris Athletic Complex are top sights worth seeing.
Midtown
Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or The DoSeum while you're exploring the area.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
Tobin Hill
Tobin Hill might not have many top sights, but San Antonio Zoo and Aquarium and San Antonio Museum of Art are two attractions nearby that you can check out.
Uptown
If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.
Alamo Heights
You'll enjoy the museums and coffee shops in Alamo Heights. You might want to make time for a stop at San Antonio River or Toilet Seat Museum.
