Medical Center District Travel Guide

San Antonio

Photo by Linda Cronan

Popular places to visit


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
The price is 2.338.992 ₫ per night from 13 Oct to 14 Oct
2.338.992 ₫
2.764.646 ₫ total
13 Oct - 14 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,983 reviews)
"Hotel clean good breakfast. Only disadvantage is they are now charging for parking. It is not advertised on the website parking fee per night."

Reviewed on 6 Oct 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410, San Antonio, TX
The price is 2.344.260 ₫ per night from 13 Oct to 14 Oct
2.344.260 ₫
2.785.877 ₫ total
13 Oct - 14 Oct
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free local area shuttle and room service. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,007 reviews)
"The building the restaurant the bar the room everything was lovely. The only minor issues I had were the toilet paper holder was coming out of the drywall and there was what looked like gunk (didn’t look like mold) around the border of the bathroom mirror"

Reviewed on 6 Oct 2025

San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 out of 5
7203 Wurzbach Road, San Antonio, TX
The price is 2.317.920 ₫ per night from 26 Oct to 27 Oct
2.317.920 ₫
2.706.171 ₫ total
26 Oct - 27 Oct
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,007 reviews)
"Friendly helpful staff. Awesome experience!!"

Reviewed on 3 Oct 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr, San Antonio, TX
The price is 2.216.511 ₫ per night from 19 Oct to 20 Oct
2.216.511 ₫
2.620.116 ₫ total
19 Oct - 20 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,005 reviews)
"Clean room and quiet hotel comfortable beds. Nice courtyard also"

Reviewed on 10 Oct 2025

Courtyard by Marriott Medical Center San Antonio
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is 3.342.546 ₫ per night from 30 Oct to 31 Oct
3.342.546 ₫
4.666.921 ₫ total
30 Oct - 31 Oct
includes taxes & fees
Stay at this 4.5-star luxury hotel in San Antonio. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the bar and the helpful ...
9.4/10 Exceptional! (2,032 reviews)
"Everything was super close by to the hotel, the Wifi wasn’t working due to a bursted pipe but aside from that it was an okay stay. Staff was extremely kind"

Reviewed on 8 Oct 2025

Hotel Valencia Riverwalk
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

3 out of 5
105 S Saint Marys Street, San Antonio, TX
The price is 3.160.537 ₫ per night from 19 Oct to 20 Oct
3.160.537 ₫
3.736.066 ₫ total
19 Oct - 20 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (3,825 reviews)
"Excellent location right on the riverwalk. Near pubs and great restaurants. The Alamo is about a 10 minute walk. Its a beautiful place just for a nice walk. Room was affordable and nice. We had free breafast included every morning and there is a free cocktail party in the early afternoon.. i would ..."

Reviewed on 6 Oct 2025

Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

Tobin Hill might not have many top sights, but Alamo and San Antonio Museum of Art are two attractions nearby that you can check out.

Tobin Hill
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Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Uptown
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Alamo Heights

You'll enjoy the museums and coffee shops in Alamo Heights. You might want to make time for a stop at San Antonio River or Toilet Seat Museum.

Alamo Heights


Medical Center District Travel Guide

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