Medical Center District Travel Guide
San Antonio
Visit Medical Center District
Popular places to visit
South Texas Medical Center
If South Texas Medical Center is what brings you to town, hopefully you'll have a chance to explore more of San Antonio.
River Walk
River Walk is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the acclaimed theatre scene and shops in this walkable area.
Six Flags Fiesta Texas
Enjoy the excitement at Six Flags Fiesta Texas and see why people love this theme park in San Antonio. Experience the acclaimed theatre scene and entertainment choices in this family-friendly area.
Lackland Air Force Base
Lackland Air Force Base is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the entertainment venues and shops in this family-friendly area.
Alamo
You can browse the exhibits at Alamo, a museum with a story of its own, during your trip to San Antonio. Experience the entertainment choices and fascinating museums in this walkable area.
Alamodome
Catch an event at Alamodome during your trip to San Antonio. Experience the acclaimed theatre scene and lively festivals in this walkable area.
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
The room was spotless & the people there was so nice, helpful. Im so thankful. I absolutely recommend this place.
Reviewed on 11 Jan 2026
San Antonio Marriott Northwest Medical Center
Great hotel and amenities, clean, nice bar area and attentive staff.
Reviewed on 8 Jan 2026
Park Inn by Radisson
Convenient for those who has a love one’s in Methodist Hospital
Reviewed on 7 Jan 2026
Hotel Valencia Riverwalk
The stay was so wonderful, it was a very beautiful room, extra friendly staff and a lovely time all around!
Reviewed on 12 Jan 2026
Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Friendly staff. Clean facilities. Lots of amenities like a putting green & lots of nighttime lights. Loved the several Fire Pits. Enjoyed the whole place...Steam room was awesome too & we were surprised how long the water slides stayed open...NICE !!
Reviewed on 12 Jan 2026
Riverwalk Plaza
Great stay. Older hotel but service was good. Hotel was clean.
Reviewed on 12 Jan 2026
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Other neighbourhoods around Medical Center District
Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.
Shearer Hills - Ridgeview
While visiting Shearer Hills - Ridgeview, you might make a stop by sights like North Star Mall and San Pedro Driving Range & Par 3 Course.
Midtown
Unique features of Midtown include the river views and bars. Make a stop by San Antonio River or The DoSeum while you're exploring the area.
La Cantera District
If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.
Tobin Hill
Tobin Hill might not have many top sights, but San Antonio River and San Antonio Museum of Art are two attractions nearby that you can check out.
Uptown
If you're spending some time in Uptown, San Antonio River and Marion Koogler McNay Art Museum are top sights worth seeing.
