Medical Center District Travel Guide

San Antonio

Photo by Linda Cronan

Popular places to visit


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
The price is 2.332.954 ₫ per night from 18 Aug to 19 Aug
2.332.954 ₫
2.757.510 ₫ total
18 Aug - 19 Aug
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,870 reviews)
"It was good rooms and facility clean. I was however taken back by the $10 charge for parking. I don't think that fair."

Reviewed on 15 Aug 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is 2.338.208 ₫ per night from 31 Aug to 1 Sept
2.338.208 ₫
2.778.684 ₫ total
31 Aug - 1 Sept
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free local area shuttle and room service. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,001 reviews)
"A good place for a quick, one-night stay. I had to stay somewhere overnight for work-related reasons and chose this Marriot. Room was spacious. Bed was large and comfortable. The only drawback for me was the location is right at the intersection of Interstate 10 and loop 410. All of the roads you ..."

Reviewed on 13 Aug 2025

San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 out of 5
7203 Wurzbach Road, San Antonio, TX
The price is 2.417.024 ₫ per night from 24 Aug to 25 Aug
2.417.024 ₫
2.821.875 ₫ total
24 Aug - 25 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (976 reviews)
"Hair shampoo and conditioner bottles need to be filled up each time a new guest checks into room."

Reviewed on 14 Aug 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr, San Antonio, TX
The price is 2.434.101 ₫ per night from 24 Aug to 25 Aug
2.434.101 ₫
2.877.326 ₫ total
24 Aug - 25 Aug
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,002 reviews)
"The stay was great overall. The only issue was the elevator was out."

Reviewed on 14 Aug 2025

Courtyard by Marriott Medical Center San Antonio
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the ...
8/10 Very Good! (5,699 reviews)
"I liked the valet guys. The room was very nice. I didn't like the mixed information about late check out. I did want a late check out because I wanted to attend mass at the Sam Fernando church, but it started at ten and would last til eleven. Not giving us time to return to the room to change and ..."

Reviewed on 17 Aug 2025

Riverwalk Plaza
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

3 out of 5
105 S Saint Marys Street, San Antonio, TX
The price is 3.362.553 ₫ per night from 22 Aug to 23 Aug
3.362.553 ₫
3.974.953 ₫ total
22 Aug - 23 Aug
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the pool ...
9.2/10 Wonderful! (3,631 reviews)
"Super family friendly."

Reviewed on 16 Aug 2025

Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Los Angeles Heights

While Northwest Los Angeles Heights may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Alamo and Alamodome.

Northwest Los Angeles Heights
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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

While visiting Tobin Hill, you might make a stop by sights like San Antonio River and Temple Beth-El.

Tobin Hill
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Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Uptown

Medical Center District Travel Guide

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