Medical Center District Travel Guide

San Antonio

Photo by Linda Cronan

Popular places to visit


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is 2.194.886 ₫ per night from 3 Dec to 4 Dec
2.194.886 ₫
2.594.843 ₫ total
3 Dec - 4 Dec
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (3,079 reviews)
Excellent customer service, super clean and the hotel is very nice, I loved it, it's my first time staying here and I don't think it will be the last.

Reviewed on 23 Nov 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is 2.241.790 ₫ per night from 30 Nov to 1 Dec
2.241.790 ₫
2.663.975 ₫ total
30 Nov - 1 Dec
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy a free local area shuttle, room service and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,021 reviews)
Very friendly & helpful staff, clean & comfortable rooms. A pretty bar area and delicious breakfast for room service. We will definitely stay there again!

Reviewed on 24 Nov 2025

San Antonio Marriott Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
The price is 2.218.615 ₫ per night from 7 Dec to 8 Dec
2.218.615 ₫
2.622.602 ₫ total
7 Dec - 8 Dec
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,006 reviews)
Room was clean, staff was very friendly!!

Reviewed on 19 Nov 2025

Courtyard by Marriott Medical Center San Antonio
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is 2.762.607 ₫ per night from 14 Dec to 15 Dec
2.762.607 ₫
4.019.156 ₫ total
14 Dec - 15 Dec
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
9.4/10 Exceptional! (2,173 reviews)
An amazing experience

Reviewed on 27 Nov 2025

Hotel Valencia Riverwalk
Crockett Hotel

Crockett Hotel

3 out of 5
320 Bonham San Antonio TX
The price is 2.122.826 ₫ per night from 2 Dec to 3 Dec
2.122.826 ₫
2.509.372 ₫ total
2 Dec - 3 Dec
includes taxes & fees
Stay at this historic hotel in San Antonio. Enjoy free Wi-Fi, valet parking (surcharge) and a 24-hour front desk. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,507 reviews)
Everything was good. We Had room 213 and outside our window you could see the front desk and at midnight when we were trying to sleep a drunk man and the clerk were talking loud for 20 min straight, they both were super loud and it felt they were in our room but other than that it was good

Reviewed on 24 Nov 2025

Crockett Hotel
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the ...
8/10 Very Good! (6,137 reviews)
.

Reviewed on 27 Nov 2025

Riverwalk Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

Northwest Side
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

Tobin Hill might not have many top sights, but San Antonio Museum of Art and Historic Brackenridge Golf Course are two attractions nearby that you can check out.

Tobin Hill
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Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Uptown
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Alamo Heights

You'll enjoy the museums and coffee shops in Alamo Heights. You might want to make time for a stop at San Antonio River or Harry B Orem Stadium.

Alamo Heights


Medical Center District Travel Guide

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