Medical Center District Travel Guide

San Antonio

Photo by Linda Cronan

Popular places to visit


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
The price is 2.317.236 ₫ per night from 1 Jul to 2 Jul
2.317.236 ₫
2.738.931 ₫ total
1 Jul - 2 Jul
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,665 reviews)
"Everything was very good except that I call because I was going to do a late check in and the employee Margy was super rude"

Reviewed on 27 Jun 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical Center
3.5 out of 5
3233 NW Loop 410, San Antonio, TX
The price is 2.275.484 ₫ per night from 28 Jul to 29 Jul
2.275.484 ₫
2.703.917 ₫ total
28 Jul - 29 Jul
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free local area shuttle and room service. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,000 reviews)
"Down sides for us. There was no microwave in our room and I was told there would be, and the ice is not on every floor. It’s kept on one floor. Other than that it is well kept/clean, bed was comfortable and my room stayed cool… I can’t sleep in a hot room so this was was a major plus! Over all it ..."

Reviewed on 21 Jun 2025

San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center
2.5 out of 5
7203 Wurzbach Road, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is 2.400.740 ₫ per night from 13 Jul to 14 Jul
2.400.740 ₫
2.802.864 ₫ total
13 Jul - 14 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (890 reviews)
"The area is safe and quite."

Reviewed on 26 Jun 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Courtyard by Marriott Medical Center San Antonio
Courtyard by Marriott Medical Center San Antonio
3 out of 5
8585 Marriott Dr, San Antonio, TX
The price is 2.557.310 ₫ per night from 10 Jul to 11 Jul
2.557.310 ₫
3.022.970 ₫ total
10 Jul - 11 Jul
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,006 reviews)
"Very nice place to stay."

Reviewed on 26 Jun 2025

Courtyard by Marriott Medical Center San Antonio
Riverwalk Plaza
Riverwalk Plaza
4 out of 5
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
The price is 2.275.484 ₫ per night from 6 Jul to 7 Jul
2.275.484 ₫
2.689.828 ₫ total
6 Jul - 7 Jul
includes taxes & fees
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the ...
8/10 Very Good! (5,432 reviews)
"Close to River walk everything was within walking distance staff were pleasant and friendly"

Reviewed on 29 Jun 2025

Riverwalk Plaza
La Cantera Resort & Spa
La Cantera Resort & Spa
4 out of 5
16641 La Cantera Pkwy, San Antonio, TX
The price is 6.009.678 ₫ per night from 1 Jul to 2 Jul
6.009.678 ₫
8.562.808 ₫ total
1 Jul - 2 Jul
includes taxes & fees
Stay at this 4-star spa hotel in San Antonio. Enjoy 5 outdoor pools, a full-service spa and 5 restaurants. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (1,005 reviews)
"We splurged and stayed in the Villas. It was awesome. It comes with a golf cart to cruise around the resort. We had a patio and a pool and hot tub that was never crowded. The staff will do anything to help you. Hope we come back soon!"

Reviewed on 27 Jun 2025

La Cantera Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
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Shearer Hills - Ridgeview

While visiting Shearer Hills - Ridgeview, you might make a stop by sights like North Star Mall and Blessed Sacrament Catholic Church.

Shearer Hills - Ridgeview
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio Zoo and Aquarium or San Antonio River while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

While visiting Tobin Hill, you might make a stop by sights like San Antonio River and Temple Beth-El.

Tobin Hill
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Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and San Antonio River are top sights worth seeing.

Uptown

Medical Center District Travel Guide

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