Medical Center District Travel Guide

San Antonio

River walk in San Antonio
Tourists River Walk San Antonio Texas
Riverboat on the San Antonio River Walk, San Antonio, Texas, United States of America.
River walk in San Antonio
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Popular places to visit


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is 2.337.127 ₫ per night from 3 Jun to 4 Jun
2.337.127 ₫
2.762.442 ₫ total
3 Jun - 4 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (3,397 reviews)
"I was very disappointed in the fact of how early the pool closed the whole reason I stayed at that hotel instead of a nicer one were my son had stayed was because it has a hot tub but I never got to use it because it closed at 10 that's way too early especially when I had to pay an extra $10 to even ..."

Reviewed on 2 Jun 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is 2.818.122 ₫ per night from 14 Jun to 15 Jun
2.818.122 ₫
3.348.642 ₫ total
14 Jun - 15 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy a free local area shuttle, room service and a 24-hour fitness centre. Our guests praise the helpful ...
8.6/10 Excellent! (1,069 reviews)
"Very good"

Reviewed on 1 Jun 2026

San Antonio Marriott Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3 out of 5
9806 Interstate Hwy 10 W San Antonio TX
The price is 2.421.085 ₫ per night from 8 Jun to 9 Jun
2.421.085 ₫
2.861.940 ₫ total
8 Jun - 9 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,335 reviews)
"Just stay here , breakfast great, dinner /drinks great , pool great, hot tub great. San Antonio traffic , sucks ... But location to Lackland is great , New Braunfels great ... Staff ... And I mean all staff phenomenal ... Period"

Reviewed on 2 Jun 2026

Drury Inn & Suites San Antonio Northwest Medical Center
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
The price is 3.947.587 ₫ per night from 7 Jun to 8 Jun
3.947.587 ₫
4.666.403 ₫ total
7 Jun - 8 Jun
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (4,719 reviews)
"Everything was amazing"

Reviewed on 2 Jun 2026

Drury Plaza Hotel San Antonio Riverwalk
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is 2.889.466 ₫ per night from 22 Jun to 23 Jun
2.889.466 ₫
4.167.543 ₫ total
22 Jun - 23 Jun
includes taxes & fees
Stay at this luxury hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (2,779 reviews)
"Could not be happier with our whole experience from check in to room to dining to check out. Very well trained and friendly staff. Kudos to the management and entire staff. Great location near the River Walk! Thanks to the entire staff!"

Reviewed on 1 Jun 2026

Hotel Valencia Riverwalk
Menger Hotel

Menger Hotel

3.5 out of 5
204 Alamo Plaza San Antonio TX
The price is 2.438.455 ₫ per night from 7 Jun to 8 Jun
2.438.455 ₫
2.882.457 ₫ total
7 Jun - 8 Jun
includes taxes & fees
Stay at this historic hotel in San Antonio. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the bar in their reviews. ...
8.8/10 Excellent! (4,079 reviews)
"Minimum eating in the hotel itself. Really missed the formal dining room that use to be open for brunch and dinner."

Reviewed on 1 Jun 2026

Menger Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

The Alamo in San Antonio, Texas

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

Northwest Side
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Shearer Hills - Ridgeview

While visiting Shearer Hills - Ridgeview, you might make a stop by sights like North Star Mall and San Pedro Driving Range & Par 3 Course.

Shearer Hills - Ridgeview
River Walk in San Antonio, Texas

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio River or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
Texas Six Flags night light,2018

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
Tobin Hill

Tobin Hill

Tobin Hill might not have many top sights, but Alamo and San Antonio River are two attractions nearby that you can check out.

Tobin Hill
Dallas Skyline Reflection on Trinity River During Sunset, Dallas, Texas.

Uptown

If you're spending some time in Uptown, San Antonio River and Alamo Quarry Market are top sights worth seeing.

Uptown


Medical Center District Travel Guide

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