Compare and book 3 Star hotels in Medical Center District, San Antonio

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Medical Center District 3 Star Hotels

This weekend
Next weekend

Top Medical Center District 3 Star Hotels

Crockett Hotel

3.0 star property
Downtown San Antonio
9.0 out of 10, Wonderful, (2500)
"Fabulous place to stay, highly recommend "
United States
Lisa
The price is 2.215.152 ₫
2.618.509 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Crockett Hotel

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

3.0 star property
Downtown San Antonio
7.8 out of 10, Good, (3757)
"The room is clean and staff is friendly"
United States
Michelle
The price is 1.874.409 ₫
2.677.336 ₫ total
includes taxes & fees
14 Dec - 15 Dec
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

3.0 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (4081)
"Very nice stay."
United States
Anthony
The price is 3.163.296 ₫
3.739.328 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Drury Plaza Hotel San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3.0 star property
Medical Center District
8.4 out of 10, Very good, (3099)
"quite place with good breakfast"
United States
Juan
The price is 2.341.034 ₫
2.767.060 ₫ total
includes taxes & fees
7 Dec - 8 Dec
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Spark By Hilton San Antonio Northwest near Six Flags

3.0 star property
La Cantera District
7.8 out of 10, Good, (1777)
"Great stay "
United States
Katherine
The price is 1.550.144 ₫
1.840.548 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Spark By Hilton San Antonio Northwest near Six Flags

Menger Hotel

3.5 star property
Downtown San Antonio
9.0 out of 10, Wonderful, (3555)
"Historic and classy, and you can beat the location."
United States
Warren
The price is 2.471.531 ₫
2.921.572 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Menger Hotel

La Quinta Inn & Suites by Wyndham San Antonio Downtown

3.0 star property
Downtown San Antonio
9.0 out of 10, Wonderful, (3114)
"Very clean hotel and friendly staff"
United States
antonio
The price is 2.097.440 ₫
2.479.362 ₫ total
includes taxes & fees
15 Dec - 16 Dec
La Quinta Inn & Suites by Wyndham San Antonio Downtown

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

3.5 star property
Far West Side
9.0 out of 10, Wonderful, (1267)
"Awesome place to stay at "
United States
Diego
The price is 1.877.046 ₫
3.307.629 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Sonesta ES Suites San Antonio Downtown Alamo Plaza

3.0 star property
Downtown San Antonio
8.4 out of 10, Very good, (1876)
"Staff and location! Also the room was very comfortable! "
United States
Jose Luis
The price is 2.293.581 ₫
2.711.219 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Sonesta ES Suites San Antonio Downtown Alamo Plaza

La Quinta Inn & Suites By Wyndham San Antonio At The Rim

3.0 star property
Forest Crest
9.2 out of 10, Wonderful, (798)
"Great place to stay!! "
United States
Stacy
The price is 2.218.446 ₫
2.590.036 ₫ total
includes taxes & fees
8 Dec - 9 Dec
La Quinta Inn & Suites By Wyndham San Antonio At The Rim

Embassy Suites San Antonio Riverwalk-Downtown

3.5 star property
Downtown San Antonio
9.0 out of 10, Wonderful, (1333)
"Great stay!"
United States
Maricella
The price is 3.353.374 ₫
3.984.552 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Embassy Suites San Antonio Riverwalk-Downtown

La Quinta Inn & Suites by Wyndham San Antonio Airport

3.0 star property
Uptown
7.6 out of 10, Good, (2800)
"Courteous staff , clean bed & bathrooms"
United States
Ralph
The price is 1.982.498 ₫
2.343.407 ₫ total
includes taxes & fees
14 Dec - 15 Dec
La Quinta Inn & Suites by Wyndham San Antonio Airport

Holiday Inn San Antonio - Riverwalk by IHG

3.0 star property
Downtown San Antonio
8.4 out of 10, Very good, (1164)
"great place to stay"
United States
Enrique
The price is 2.510.519 ₫
2.967.660 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Holiday Inn San Antonio - Riverwalk by IHG

Courtyard by Marriott San Antonio SeaWorld - Westover Hills

3.0 star property
Far West Side
8.6 out of 10, Excellent, (1080)
"good hotel"
United States
Deborah
The price is 2.442.532 ₫
2.902.584 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Courtyard by Marriott San Antonio SeaWorld - Westover Hills

Hyatt Place San Antonio–North/Stone Oak

3.0 star property
Stone Oak
8.8 out of 10, Excellent, (1001)
"Great Stay! "
United States
Rachel
The price is 2.609.937 ₫
3.084.998 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Hyatt Place San Antonio–North/Stone Oak

San Antonio Marriott Northwest Medical Center

3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1001)
"The room is clean and the hotel staff are all nice including the staff from the restourant"
United States
Frank Charles
The price is 2.346.307 ₫
2.788.309 ₫ total
includes taxes & fees
7 Dec - 8 Dec
San Antonio Marriott Northwest Medical Center

Drury Inn & Suites San Antonio Riverwalk

3.0 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (1746)
"location and value are really great "
United States
Michael D.
The price is 3.163.296 ₫
3.739.328 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Drury Inn & Suites San Antonio Riverwalk

Drury Plaza Hotel San Antonio Airport

3.0 star property
Uptown
9.4 out of 10, Exceptional, (1924)
"Great hotel in the center of everything. Loved all the food benefits and felt safe, nice parking too!"
United States
Ashley
The price is 2.372.406 ₫
2.804.232 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Drury Plaza Hotel San Antonio Airport

The Inn at Market Square

3.0 star property
Downtown San Antonio
4.0 out of 10, (656)
"Some of the hotel rooms had padlocks and there was a cop investigating a crime on the property. This place should not even be on the list, Expedia do better."
United States
Victoria
The price is 1.273.333 ₫
1.486.873 ₫ total
includes taxes & fees
7 Dec - 8 Dec
The Inn at Market Square

La Quinta Inn by Wyndham San Antonio I-35 N at Toepperwein

3.0 star property
Live Oak
5.6 out of 10, (1429)
"Very good "
United States
Luis
The price is 1.322.506 ₫
1.517.576 ₫ total
includes taxes & fees
21 Dec - 22 Dec
La Quinta Inn by Wyndham San Antonio I-35 N at Toepperwein
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 3-star hotels. See all 4-star hotels in Medical Center District.
Still don't see what you're looking for?
See all properties in Medical Center District.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Medical Center District Hotel Reviews

Frequently asked questions

What are the best 3-star hotels in Medical Centre District?
For a comfortable holiday in or near Medical Centre District, consider booking Courtyard by Marriott Medical Centre San Antonio. This 3-star hotel is among the top-rated properties in the area based on reviews by Expedia customers.
How much does it cost to stay in a 3-star hotel in Medical Centre District?
Use Expedia's search filters to lock in a wallet-friendly 3-star hotel for your Medical Centre District escape. Simply set your maximum rate with our pricing tool. You can also choose the amenities you need, neighbourhood and plenty more.

  • Search for the lowest price per night right now from 3.811.664 ₫

What is the difference between a 4-star and 3-star hotel in Medical Centre District?
The big difference between a 3- and 4-star hotel in Medical Centre District is the quality of service and access to creature comforts. Three-star hotels are usually lower priced and offer the services and amenities required to be comfortable, such as a gym, breakfast and WiFi. You can expect a little bit more at a 4-star hotel — think upmarket décor, premium toiletries and perks like spa and wellness centres.