Compare and book 4 Star hotels in Medical Center District, San Antonio

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Check availability on Medical Center District 4 Star Hotels

Tonight
28 Nov - 29 Nov
Tomorrow
29 Nov - 30 Nov
This weekend
28 Nov - 30 Nov
Next weekend
5 Dec - 7 Dec

Top Medical Center District 4 Star Hotels

Terrace/patio
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (2176)
"Place was really great, great service and food, great location."
United States
Ward
The price is 2.762.397 ₫
4.018.850 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel Valencia Riverwalk
Games room
Riverwalk Plaza

Riverwalk Plaza

4.0 star property
Downtown San Antonio
8.2 out of 10, Very good, (6144)
"Yes beautiful hotel"
United States
MARYLUZ
Riverwalk Plaza
Breakfast, lunch, dinner served; Italian cuisine
The Westin Riverwalk, San Antonio

The Westin Riverwalk, San Antonio

4.0 star property
Downtown San Antonio
8.8 out of 10, Excellent, (1416)
"Clean room, very helpful staff. "
United States
Abby
The price is 4.098.209 ₫
4.880.846 ₫ total
includes taxes & fees
21 Dec - 22 Dec
The Westin Riverwalk, San Antonio
Balcony view
Omni La Mansion del Rio

Omni La Mansion del Rio

4.0 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (2797)
"Overall a great place To stay!"
United States
Scott
The price is 5.248.690 ₫
6.297.584 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Omni La Mansion del Rio
Terrace/patio
Hotel Contessa

Hotel Contessa

4.0 star property
Downtown San Antonio
9.0 out of 10, Wonderful, (3411)
"Great stay"
United States
Trent
The price is 3.009.273 ₫
4.078.909 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hotel Contessa
Outdoor pool, open 9:00 AM to 10:00 PM, pool cabanas (surcharge)
Plaza San Antonio Hotel & Spa, Autograph Collection

Plaza San Antonio Hotel & Spa, Autograph Collection

4.0 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (674)
"Clean and comfy rooms, reception staff very friendly "
United States
Adriana
The price is 4.012.804 ₫
5.442.973 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Plaza San Antonio Hotel & Spa, Autograph Collection
Exterior
InterContinental San Antonio Riverwalk by IHG

InterContinental San Antonio Riverwalk by IHG

4.5 star property
Downtown San Antonio
9.2 out of 10, Wonderful, (623)
"Love this hotel !"
United States
Amber
The price is 3.776.757 ₫
5.510.459 ₫ total
includes taxes & fees
14 Dec - 15 Dec
InterContinental San Antonio Riverwalk by IHG
View from property
Hyatt Regency San Antonio Riverwalk

Hyatt Regency San Antonio Riverwalk

4.0 star property
Downtown San Antonio
9.2 out of 10, Wonderful, (1901)
"Great hotel"
United States
David
The price is 4.012.500 ₫
5.672.881 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hyatt Regency San Antonio Riverwalk
Premium bedding, pillow-top beds, in-room safe, desk
Grand Hyatt San Antonio River Walk

Grand Hyatt San Antonio River Walk

4.0 star property
Downtown San Antonio
9.2 out of 10, Wonderful, (1310)
"everything was fine, very nice stay"
United States
Matthew
The price is 3.788.338 ₫
5.328.653 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Grand Hyatt San Antonio River Walk
2 restaurants, breakfast, lunch, dinner served; American cuisine
The St. Anthony, A Luxury Collection Hotel, San Antonio

The St. Anthony, A Luxury Collection Hotel, San Antonio

4.5 star property
Downtown San Antonio
8.8 out of 10, Excellent, (1007)
"Great hotel! "
United States
Kace
The price is 4.012.500 ₫
4.743.136 ₫ total
includes taxes & fees
22 Dec - 23 Dec
The St. Anthony, A Luxury Collection Hotel, San Antonio
Terrace/patio
Canopy by Hilton San Antonio Riverwalk

Canopy by Hilton San Antonio Riverwalk

4.0 star property
Downtown San Antonio
9.2 out of 10, Wonderful, (1587)
"We stay here every time we are in San Antonio and we love it!!"
United States
Shedrick
The price is 4.368.589 ₫
5.876.163 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Canopy by Hilton San Antonio Riverwalk
Outdoor pool
Kimpton Santo San Antonio - Riverwalk by IHG

Kimpton Santo San Antonio - Riverwalk by IHG

4.5 star property
Downtown San Antonio
9.4 out of 10, Exceptional, (620)
"Really beautiful hotel"
United States
BREE
The price is 3.565.765 ₫
5.013.305 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Kimpton Santo San Antonio - Riverwalk by IHG
Rooftop terrace
AC Hotel by Marriott San Antonio Riverwalk

AC Hotel by Marriott San Antonio Riverwalk

4.0 star property
Downtown San Antonio
9.0 out of 10, Wonderful, (1031)
"Room was nice great service. "
United States
Randy
The price is 3.006.636 ₫
3.554.114 ₫ total
includes taxes & fees
14 Dec - 15 Dec
AC Hotel by Marriott San Antonio Riverwalk
Indoor pool, outdoor pool
The Westin San Antonio North

The Westin San Antonio North

4.0 star property
Vance Jackson
8.6 out of 10, Excellent, (1197)
"Great place to stay! "
United States
Susan
The price is 2.229.922 ₫
2.675.266 ₫ total
includes taxes & fees
7 Dec - 8 Dec
The Westin San Antonio North
Restaurant
Hilton Palacio Del Rio

Hilton Palacio Del Rio

4.0 star property
Downtown San Antonio
8.8 out of 10, Excellent, (1083)
"Great location and overall great stay! "
United States
Arnose
The price is 4.236.662 ₫
5.008.116 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hilton Palacio Del Rio
4 outdoor pools, pool cabanas (surcharge), pool umbrellas
JW Marriott San Antonio Hill Country Resort & Spa

JW Marriott San Antonio Hill Country Resort & Spa

4.5 star property
San Antonio
9.0 out of 10, Wonderful, (1009)
"Another amazing stay !!"
United States
Richmond
The price is 8.272.205 ₫
11.570.492 ₫ total
includes taxes & fees
7 Dec - 8 Dec
JW Marriott San Antonio Hill Country Resort & Spa
Water view
Mokara Hotel & Spa San Antonio

Mokara Hotel & Spa San Antonio

4.5 star property
Downtown San Antonio
9.6 out of 10, Exceptional, (1010)
"great place to stay"
United States
Perry
The price is 6.831.130 ₫
8.094.973 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Mokara Hotel & Spa San Antonio
Exterior
DoubleTree by Hilton San Antonio Downtown

DoubleTree by Hilton San Antonio Downtown

4.0 star property
Vista Verde South
8.2 out of 10, Very good, (1009)
"Always a clean place to stay in the staff is always amazing"
United States
James
The price is 1.855.411 ₫
2.193.264 ₫ total
includes taxes & fees
14 Dec - 15 Dec
DoubleTree by Hilton San Antonio Downtown
3 outdoor pools, pool cabanas (surcharge), pool loungers
Hyatt Regency Hill Country Resort and Villas

Hyatt Regency Hill Country Resort and Villas

4.0 star property
Far West Side
8.8 out of 10, Excellent, (1005)
"Great stay"
United States
Lisa
The price is 7.621.508 ₫
10.414.074 ₫ total
includes taxes & fees
5 Dec - 6 Dec
Hyatt Regency Hill Country Resort and Villas
Exterior
Signia by Hilton La Cantera Resort & Spa

Signia by Hilton La Cantera Resort & Spa

4.0 star property
La Cantera District
9.0 out of 10, Wonderful, (1037)
"Great stay new hotel huge family friendly "
United States
Diane
The price is 6.883.614 ₫
9.826.306 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Signia by Hilton La Cantera Resort & Spa
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Medical Center District.
Thompson San Antonio - Riverwalk, by Hyatt

Thompson San Antonio - Riverwalk, by Hyatt

115 Lexington Avenue San Antonio TX
The price is 4.723.225 ₫ per night from 26 Dec to 27 Dec
4.723.225 ₫
6.480.578 ₫ total
26 Dec - 27 Dec
includes taxes & fees
9/10 Wonderful! (909 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Medical Center District Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Medical Centre District?
Put your suitcase down and relax into your holiday at The Westin San Antonio North. This 4-star hotel is one of Expedia's travellers' top picks around Medical Centre District.
How much does it cost to stay in a 4-star hotel in Medical Centre District?
We can help you quickly find the ideal 4-star hotel for your trip to Medical Centre District. Use our handy filter tool to tailor your search by things like budget, amenities and star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from 6.480.578 ₫

What's the difference between 5-star and 4-star hotels in Medical Centre District?
Give yourself the luxury treatment during your Medical Centre District escape by choosing a 4-star hotel. As well as featuring upmarket surroundings, these retreats are typically packed with amenities such as large beds, complimentary bathrobes and more. A 5-star hotel will go the extra mile to make your trip an even more lavish and unforgettable one. Concierge assistance, elegant furnishings and world-class dining are a few of the first-rate conveniences and services you'll likely have access to.

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