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Compare and book 4 Star hotels in Medical Center District, San Antonio

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Check availability on Medical Center District 4 Star Hotels

Top Medical Center District 4 Star Hotels

Riverwalk Plaza
Games room

Riverwalk Plaza

4.0 star property
8.2 out of 10, Very good, (5701)
"Good place to stay"
Riverwalk Plaza
InterContinental San Antonio Riverwalk by IHG
Exterior

InterContinental San Antonio Riverwalk by IHG

4.5 star property
9.4 out of 10, Exceptional, (522)
"Great place to stay! "
The price is 3.776.846 ₫
5.362.638 ₫ total
includes taxes & fees
28 Aug - 29 Aug
InterContinental San Antonio Riverwalk by IHG
La Cantera Resort & Spa
Property grounds

La Cantera Resort & Spa

4.0 star property
9.0 out of 10, Wonderful, (1001)
"We had a great stay. "
The price is 9.770.633 ₫
13.075.537 ₫ total
includes taxes & fees
24 Aug - 25 Aug
La Cantera Resort & Spa
Omni La Mansion del Rio
Balcony view

Omni La Mansion del Rio

4.0 star property
9.4 out of 10, Exceptional, (2678)
"Great stay!"
The price is 4.294.018 ₫
5.152.054 ₫ total
includes taxes & fees
4 Sept - 5 Sept
Omni La Mansion del Rio
Hotel Contessa
Terrace/patio

Hotel Contessa

4.0 star property
9.0 out of 10, Wonderful, (3188)
"Great place to stay. Excellent location and the staff is amazing."
Hotel Contessa
The Westin San Antonio North
Indoor pool, outdoor pool

The Westin San Antonio North

4.0 star property
8.6 out of 10, Excellent, (1053)
"Great place to stay."
The price is 2.073.124 ₫
2.488.478 ₫ total
includes taxes & fees
1 Sept - 2 Sept
The Westin San Antonio North
JW Marriott San Antonio Hill Country Resort & Spa
4 outdoor pools, pool cabanas (surcharge), pool umbrellas

JW Marriott San Antonio Hill Country Resort & Spa

4.5 star property
9.0 out of 10, Wonderful, (1001)
"Great family oriented place !"
The price is 9.183.237 ₫
12.574.720 ₫ total
includes taxes & fees
28 Aug - 29 Aug
JW Marriott San Antonio Hill Country Resort & Spa
Hotel Valencia Riverwalk
Terrace/patio

Hotel Valencia Riverwalk

4.5 star property
9.4 out of 10, Exceptional, (1981)
"It was a great stay! Best hotel we've stayed at in San Antonio. "
The price is 4.073.252 ₫
5.498.890 ₫ total
includes taxes & fees
4 Sept - 5 Sept
Hotel Valencia Riverwalk
Plaza San Antonio Hotel & Spa, Autograph Collection
Outdoor pool, open 9:00 AM to 10:00 PM, pool cabanas (surcharge)

Plaza San Antonio Hotel & Spa, Autograph Collection

4.0 star property
9.2 out of 10, Wonderful, (573)
"Great place everything is amazing "
The price is 3.556.202 ₫
4.998.443 ₫ total
includes taxes & fees
22 Aug - 23 Aug
Plaza San Antonio Hotel & Spa, Autograph Collection
The Westin Riverwalk, San Antonio
Breakfast, lunch, dinner served; Italian cuisine

The Westin Riverwalk, San Antonio

4.0 star property
8.8 out of 10, Excellent, (1298)
"Wonderful stay"
The price is 3.978.526 ₫
4.738.235 ₫ total
includes taxes & fees
24 Aug - 25 Aug
The Westin Riverwalk, San Antonio
Hyatt Regency Hill Country Resort & Spa
3 outdoor pools, pool cabanas (surcharge), pool loungers

Hyatt Regency Hill Country Resort & Spa

4.0 star property
8.8 out of 10, Excellent, (1004)
"Excellent and beautiful. Loved it!"
The price is 5.052.096 ₫
7.572.056 ₫ total
includes taxes & fees
24 Aug - 25 Aug
Hyatt Regency Hill Country Resort & Spa
Kimpton Santo San Antonio - Riverwalk by IHG
Outdoor pool

Kimpton Santo San Antonio - Riverwalk by IHG

4.5 star property
9.2 out of 10, Wonderful, (447)
"Amazing stay!"
The price is 3.553.364 ₫
4.876.377 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Kimpton Santo San Antonio - Riverwalk by IHG
AC Hotel by Marriott San Antonio Riverwalk
Rooftop terrace

AC Hotel by Marriott San Antonio Riverwalk

4.0 star property
9.0 out of 10, Wonderful, (884)
"Clean and friendly and staff"
The price is 3.128.748 ₫
3.698.462 ₫ total
includes taxes & fees
25 Aug - 26 Aug
AC Hotel by Marriott San Antonio Riverwalk
Grand Hyatt San Antonio River Walk
Premium bedding, pillow-top beds, in-room safe, desk

Grand Hyatt San Antonio River Walk

4.0 star property
9.0 out of 10, Wonderful, (1236)
"Great food !"
The price is 4.377.618 ₫
6.022.655 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Grand Hyatt San Antonio River Walk
Hyatt Regency San Antonio Riverwalk
View from property

Hyatt Regency San Antonio Riverwalk

4.0 star property
9.2 out of 10, Wonderful, (1788)
"We love and enjoyed our stay!"
The price is 3.525.757 ₫
5.094.686 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Hyatt Regency San Antonio Riverwalk
Element San Antonio Riverwalk
Restaurant

Element San Antonio Riverwalk

4.0 star property
9.0 out of 10, Wonderful, (974)
"Wonderful hotel with excellent staff and amenities. "
The price is 2.918.412 ₫
3.449.827 ₫ total
includes taxes & fees
26 Aug - 27 Aug
Element San Antonio Riverwalk
Canopy by Hilton San Antonio Riverwalk
Terrace/patio

Canopy by Hilton San Antonio Riverwalk

4.0 star property
9.2 out of 10, Wonderful, (1528)
"Great location, right on the riverwalk. Walkable to shopping and dining and the staff was wonderful! Would definitely stay there again."
The price is 3.256.790 ₫
4.559.822 ₫ total
includes taxes & fees
25 Aug - 26 Aug
Canopy by Hilton San Antonio Riverwalk
The St. Anthony, A Luxury Collection Hotel, San Antonio
2 restaurants, breakfast, lunch, dinner served; American cuisine

The St. Anthony, A Luxury Collection Hotel, San Antonio

4.5 star property
8.8 out of 10, Excellent, (1002)
"Really enjoyed stay!! Staff was super friendly!! We d"
The price is 4.443.348 ₫
5.252.353 ₫ total
includes taxes & fees
1 Sept - 2 Sept
The St. Anthony, A Luxury Collection Hotel, San Antonio
Marriott San Antonio Airport
Lobby

Marriott San Antonio Airport

4.0 star property
8.4 out of 10, Very good, (1000)
"Great location close to the airport. "
The price is 2.920.743 ₫
3.452.582 ₫ total
includes taxes & fees
6 Sept - 7 Sept
Marriott San Antonio Airport
Hilton Garden Inn San Antonio Downtown Riverwalk
Reception

Hilton Garden Inn San Antonio Downtown Riverwalk

4.0 star property
8.4 out of 10, Very good, (1002)
"Very Good hotel "
The price is 2.210.292 ₫
2.636.636 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Hilton Garden Inn San Antonio Downtown Riverwalk
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Medical Center District.
Thompson San Antonio - Riverwalk, by Hyatt

Thompson San Antonio - Riverwalk, by Hyatt

115 Lexington Avenue, San Antonio, TX
The price is 5.117.738 ₫ per night from 25 Aug to 26 Aug
5.117.738 ₫
6.945.783 ₫ total
25 Aug - 26 Aug
includes taxes & fees
9/10 Wonderful! (825 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Medical Center District Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Medical Centre District?
Put your suitcase down and relax into your holiday at The Westin San Antonio North. This 4-star hotel is one of Expedia's travellers' top picks around Medical Centre District.
How much does it cost to stay in a 4-star hotel in Medical Centre District?
We can help you quickly find the ideal 4-star hotel for your trip to Medical Centre District. Use our handy filter tool to tailor your search by things like budget, amenities and star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from 5.117.738 ₫

What's the difference between 5-star and 4-star hotels in Medical Centre District?
Give yourself the luxury treatment during your Medical Centre District escape by choosing a 4-star hotel. As well as featuring upmarket surroundings, these retreats are typically packed with amenities such as large beds, complimentary bathrobes and more. A 5-star hotel will go the extra mile to make your trip an even more lavish and unforgettable one. Concierge assistance, elegant furnishings and world-class dining are a few of the first-rate conveniences and services you'll likely have access to.