Compare and book 5 Star hotels in St. Charles, St. Louis

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Check availability on St. Charles 5 Star Hotels

Tonight
18 Apr - 19 Apr
Tomorrow
19 Apr - 20 Apr
Next weekend
24 Apr - 26 Apr
In two weeks
1 May - 3 May

Our top choices for St. Charles 5-star hotels

Meeting facility

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (564 reviews)
"Excellent hotel with various restaurants and expansive lobby area.. staff very attentive."
United States
Diane M
The price is 13.142.163 ₫
15.341.829 ₫ total
includes taxes & fees
10 May - 11 May
The Ritz-Carlton, St. Louis
Terrace/patio

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,001 reviews)
"The heated pool was great for the kids and the staff great"
United States
Jacob
The price is 12.378.390 ₫
14.473.928 ₫ total
includes taxes & fees
21 Apr - 22 Apr
Four Seasons Hotel St Louis
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in St. Charles.
21C Museum Hotel St Louis

21C Museum Hotel St Louis

1528 Locust street St. Louis MO
The price is 4.007.175 ₫ per night from 11 May to 12 May
4.007.175 ₫
4.817.235 ₫ total
11 May - 12 May
includes taxes & fees
9/10 Wonderful! (1,766 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

See all hotels in St. Charles
The historic 18th century Main Street through the brick paved old town of St. Charles, Missouri, along the Missouri River.

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Frequently asked questions

How much does it cost to stay in a 5-star hotel in St. Charles?
How much you pay for a 5-star hotel in St. Charles can vary depending on what time of year you travel and how long you plan to stay, among several factors. Take advantage of our price per night filter and other search tools to score the best rate on a high-end stay.

  • Search for the lowest price per night from 4.036.411 ₫

What makes a hotel 5 stars in St. Charles?
Outstanding guest service is integral to every 5-star hotel in St. Charles. From the moment you enter the lobby, staff cater to your every need, whether recommending activities and tours or providing in-room beauty treatments. Also, hotels have to offer upscale amenities to obtain a 5-star rating. These can include deluxe baths, an on-site spa, swimming pools, fine dining restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in St. Charles?
Use our filters to find an upscale escape in St. Charles where most of what you need is included. From there, narrow your results for accommodation that have a rating of 5 stars and are categorised as "All inclusive." The most important thing on the to-do list at these stays? Pure relaxation and indulgence.