Photo by Alice Andersen

Search Luxury Hotels in Clarksdale

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Clarksdale Luxury Hotels

Tonight
7 Dec - 8 Dec
Tomorrow
8 Dec - 9 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Top Clarksdale Luxury Hotels

No exact matches found, but these alternatives could be just right

Recommended hotels in Clarksdale

Front of property
Travelers Hotel

Travelers Hotel

2.5 star property
Clarksdale
9.8 out of 10, Exceptional, (276)
"Though a bit different, there was a great artsy feel to the hotel. "
United States
T
The price is 4.171.681 ₫
4.547.132 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Travelers Hotel
Reception
Hampton Inn Clarksdale

Hampton Inn Clarksdale

2.5 star property
Clarksdale
8.2 out of 10, Very good, (331)
"We would stay there again."
United States
Andrew Ray
The price is 3.493.361 ₫
3.807.763 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Clarksdale
Lobby sitting area
Quality Inn

Quality Inn

2.5 star property
Clarksdale
7.4 out of 10, Good, (705)
"Room was great! Staff is always nice and sociable."
United States
LaVonda
The price is 2.106.404 ₫
2.295.981 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Quality Inn
Lobby
Americas Best Value Inn & Suites Clarksdale

Americas Best Value Inn & Suites Clarksdale

2.5 star property
Clarksdale
6.0 out of 10, (403)
"Good location in town"
United States
Samuel
The price is 1.739.694 ₫
1.896.290 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Americas Best Value Inn & Suites Clarksdale
Restaurant
Auberge Clarksdale Blues Hostel

Auberge Clarksdale Blues Hostel

2.0 star property
Clarksdale
9.6 out of 10, Exceptional, (89)
"great stay!"
United States
mary
Auberge Clarksdale Blues Hostel
Rooftop bar
Cotton House, Cleveland, a Tribute Portfolio Hotel

Cotton House, Cleveland, a Tribute Portfolio Hotel

3.5 star property
Cleveland
9.0 out of 10, Wonderful, (617)
"Great place"
United States
Gregory
The price is 3.901.724 ₫
4.252.878 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Cotton House, Cleveland, a Tribute Portfolio Hotel
Free buffet breakfast
Holiday Inn Express Hotel & Suites Cleveland by IHG

Holiday Inn Express Hotel & Suites Cleveland by IHG

2.5 star property
Cleveland
7.8 out of 10, Good, (934)
"Was descent but under construction. I’ve stayed at better Holiday Inns"
United States
Alex
The price is 2.873.567 ₫
3.132.187 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Holiday Inn Express Hotel & Suites Cleveland by IHG
Lobby
Delta Inn

Delta Inn

2.0 star property
West Helena
6.8 out of 10, (363)
"It is a nice place to stay would like to have the same room when I come back "
United States
Janet
The price is 1.470.792 ₫
1.684.596 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Delta Inn
Desk, blackout curtains, bed sheets
Isle of Capri Casino Hotel Lula – A Caesars Rewards Destination

Isle of Capri Casino Hotel Lula – A Caesars Rewards Destination

2.5 star property
Lula
6.2 out of 10, (1001)
"I’d forgotten how peaceful this spot was- room was remodeled with microwave and mini-fridge and staff was kind! I’ll definitely revisit "
United States
Ida
The price is 1.364.285 ₫
1.487.071 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Isle of Capri Casino Hotel Lula – A Caesars Rewards Destination
Free WiFi, bed sheets
Motel 6 Cleveland, MS - Delta State University

Motel 6 Cleveland, MS - Delta State University

2.0 star property
Cleveland
8.2 out of 10, Very good, (225)
"Room is comfortable and convenient. Staff is always friendly"
United States
Brad
The price is 1.436.520 ₫
1.565.699 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Motel 6 Cleveland, MS - Delta State University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Clarksdale Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Clarksdale?
Use Expedia to arrange your flight to Tunica, MS (UTM-Tunica Municipal) airport or Greenville, MS (GLH-Mid Delta Regional) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to find what you need to make your stay special. If you want an upscale hotel with a spa, an indoor pool or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Clarksdale has to offer. During your visit, you might want to enjoy the restaurants which Clarksdale is known for.
When can I expect good weather in Clarksdale?
Planning for the weather is an important factor for making your trip to Clarksdale a success, especially when you're splurging. The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 9°C. Average annual precipitation for Clarksdale is 1403 mm.
What's there to see and do in Clarksdale?
Enjoy all that Clarksdale has to offer when you visit Delta Blues Museum, Red's Lounge and Mississippi River. If you have spare time during your trip, you might want to make a stop at The Holy Moly Theatre and Ground Zero Blues Club.