Santo Spirito Travel Guide
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art galleries and stunning cathedral in this vibrant area.
Porta Romana
Porta Romana is just one of the places to see in Arcetri, so why not enjoy the other things to explore during your travels? Discover the fascinating museums and notable monuments in this vibrant area.
Brancacci Chapel
You can learn about the history of Florence when you stop by Brancacci Chapel. Stroll along the riverfront or visit the churches in this vibrant area.
Piazza di Santa Maria Novella
After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the fascinating museums in this vibrant area.
Cathedral of Santa Maria del Fiore
Find out about the history of Cathedral of Santa Maria del Fiore, a well-known monument in Florence. Experience the acclaimed art galleries and fascinating museums in this vibrant area.
Uffizi Gallery
You can study the exhibits at Uffizi Gallery, a museum with a story of its own, during your trip to Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
Top hotels in Santo Spirito
Palazzo Mannaioni Suites
Great stay and conveniet. Room was excellent, great space and beautiful.
Reviewed on 22 Mar 2026
Foresteria Valdese di Firenze - Casa per Ferie
Room was very dated, old and cold. Shower seemed particularly dirty and the water was cold. Of the 9 hotels we have stayed in on our travels thus far this was the only 3 star that on this site rated 4.4. Good location. Lovely staff. Wouldn’t stay again.
Reviewed on 2 Jan 2026
UNA Hotels Vittoria Firenze
La Torre Del Cestello
Staff was great
Reviewed on 19 Mar 2026
Palazzo Oliveto
The room was not that clean, there was mold on the shower, there were some stains on the wall. The higienic part of the overall room is the reason why I give 2.
Reviewed on 10 Nov 2025
Casa Santo Nome di Gesù
Great
Reviewed on 21 Mar 2026
Other neighbourhoods around Santo Spirito
San Frediano
San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Boboli Gardens while you're in town.
Oltrarno
Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Piazza Santo Spirito while you're exploring the neighbourhood.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.
Historic Centre of Florence
Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are a few top attractions in Historic Centre of Florence. Hop around the city on the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop and check out the area's fascinating museums, stunning cathedral and stunning river views.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Cathedral of Santa Maria del Fiore or Piazza di Santa Maria Novella while you're exploring the neighbourhood.
