Santo Spirito Travel Guide
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art galleries and stunning cathedral in this vibrant area.
Porta Romana
Find out about the history of Arcetri when you spend time at Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.
Brancacci Chapel
You can learn about the history of Florence when you stop by Brancacci Chapel. Stroll along the riverfront or visit the notable monuments in this vibrant area.
Ponte Vecchio
Ponte Vecchio is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Visit the notable monuments and stunning cathedral in this vibrant area.
Piazza di Santa Maria Novella
After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the fascinating museums in this vibrant area.
Uffizi Gallery
You can study the exhibits at Uffizi Gallery, a museum with a story of its own, during your trip to Florence. Stroll along the riverfront or visit the churches in this vibrant area.
Top hotels in Santo Spirito
Hotel Horto Convento
Room was clean, staff from front desk to breakfast room was courteous, accommodating with brilliant smile. My husband and I had a perfect stay 👍
Reviewed on 18 Nov 2025
Palazzo Mannaioni Suites
Perfect stay
Reviewed on 18 Nov 2025
La Torre Del Cestello
What a great place. Great communication and staff. The apartment was lovely and large for our family. The location was very good and close to everything.
Reviewed on 26 Nov 2025
UNA Hotels Vittoria Firenze
Super nice reception staffs, everyone is so friendly and welcoming. But don’t like the red room decoration.
Reviewed on 5 Nov 2025
B&B Mia Palace
Extremely helpful and friendly staff.
Reviewed on 11 Oct 2025
Casa Santo Nome di Gesù
I always enjoy my stay here. Nicely located, pleasant breakfast, terrific courtyard, nicely priced.
Reviewed on 11 Nov 2025
Other neighbourhoods around Santo Spirito
San Frediano
San Frediano is known for its stunning river views, and you can plan a trip to Piazza Santo Spirito and Boboli Gardens while you're in town.
Oltrarno
Oltrarno is a destination visitors seek out for its fascinating museums, picturesque gardens and beautiful river views. You might also want to check out attractions like Pitti Palace or Piazza Santo Spirito while you're exploring the neighbourhood.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Duomo
Visitors to Duomo rave about its fascinating museums, stunning cathedral and popular shops. You might also want to make some time to see Via de' Calzaiuoli or Giotto's Campanile while you're exploring the neighbourhood.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Via de' Calzaiuoli and Piazza della Repubblica are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Santo Spirito Travel Guide
- Places of interest
- Hotels in Santo Spirito by Star Rating
- Choose Your Santo Spirito Hotel Style
- Hotels in top Florence neighborhoods
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- Piazza Santo Spirito
- Santo Spirito Basilica
- Il Nabucco di Matteo Gabellini
- Church of St Felix
- Piazza di Santa Maria Novella
- Uffizi Gallery
- Cathedral of Santa Maria del Fiore
- Piazza del Duomo
- Pitti Palace
- Mugello Circuit
- Piazza della Signoria
- Palazzo Vecchio
- Piazzale Michelangelo
- Careggi Hospital
- Fortezza da Basso
- Central Market
- Gallery of the Academy of Florence
- Basilica of Santa Maria Novella
- Antinori nel Chianti Classico
- Arno River
- Piazza San Marco
- The Mall Luxury Outlet
- Basilica of Santa Croce
- Boboli Gardens
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