Santo Spirito Travel Guide
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the acclaimed art galleries and notable monuments in this vibrant area.
Porta Romana
Find out about the history of Arcetri when you spend time at Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.
Brancacci Chapel
You can learn about the history of Florence when you stop by Brancacci Chapel. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
Uffizi Gallery
Uffizi Gallery is a top museum in Florence with a rich history. Stroll along the riverfront or visit the churches in this vibrant area.
Ponte Vecchio
Ponte Vecchio is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Visit the stunning cathedral and notable monuments in this vibrant area.
Cathedral of Santa Maria del Fiore
Find out about the history of Cathedral of Santa Maria del Fiore, a well-known monument in Florence. Experience the acclaimed art galleries and fascinating museums in this vibrant area.
Top hotels in Santo Spirito
Hotel Horto Convento
Viale Ariosto, 13, Florence, FI
The price is 4.525.333 ₫ per night from 3 Nov to 4 Nov
4.525.333 ₫
5.411.478 ₫ total
3 Nov - 4 Nov
includes taxes & fees
Stay at this 4-star hotel in Florence. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in their reviews. ...
9.6/10 Exceptional! (567 reviews)
"I thought it was great but the wife didn’t think it was completely worthy of 5 stars. She’s hard to please."
Reviewed on 30 Sept 2025
Palazzo Mannaioni Suites
Via Maffia 9 - 17r, Florence, FI
Stay at this 4-star residence in Florence. Enjoy free Wi-Fi, concierge services and satellite TV channels. Our guests praise the helpful staff in their reviews. ...
9.2/10 Wonderful! (1,033 reviews)
"The apartment is beautiful, quite large (especially by European standards), very clean, and centrally located in the Santo Spirito, and only about a 5-minute walk to Ponte Vecchio. The people at reception were all very friendly and helpful. We would definitely stay here again when in Florence."
Reviewed on 30 Sept 2025
UNA Hotels Vittoria Firenze
Via Pisana 59, Florence, FI
The price is 4.364.277 ₫ per night from 5 Oct to 6 Oct
4.364.277 ₫
5.234.317 ₫ total
5 Oct - 6 Oct
includes taxes & fees
Stay at this 4-star boutique hotel in Florence. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. ...
8.4/10 Very Good! (990 reviews)
"Amazing place, love the decor!"
Reviewed on 28 Jul 2025
La Torre Del Cestello
Via Borgo San Frediano, 8, Florence, FI
Stay at this residence in Florence. Enjoy free Wi-Fi, valet parking (surcharge) and daily housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery ...
9/10 Wonderful! (211 reviews)
"Beautiful hotel in a great location! Staff was super friendly and helpful and the price is a bargain compared to some other hotels. We had a great experience!"
Reviewed on 25 Sept 2025
Casa Santo Nome di Gesù
Piazza del Carmine, 21, Florence, FI
Stay at this guesthouse in Florence. Enjoy free breakfast, free Wi-Fi and parking (surcharge). Our guests praise the helpful staff in their reviews. Popular ...
8.8/10 Excellent! (328 reviews)
"Solo woman traveler here. Felt very safe. Loved the convenience and options of breakfast every morning. The garden is lovely and wished I had spent more time there. The room was nothing fancy, but my time there was great. Thankfully nobody was staying next door to my room because the last night I ..."
Reviewed on 26 Sept 2025
Hotel Firenze 2000
Viale Raffaello Sanzio, 16, Florence, FI
Fully refundableReserve now, pay when you stay
The price is 2.935.328 ₫ per night from 12 Oct to 13 Oct
2.935.328 ₫
3.507.612 ₫ total
12 Oct - 13 Oct
includes taxes & fees
Stay at this hotel in Florence. Enjoy free breakfast, free Wi-Fi and parking (surcharge). Popular attractions Ponte Vecchio and Uffizi Gallery are located ...
7.2/10 Good! (178 reviews)
"The breakfast was great and the room was spacious. Transit in the area was a bit unreliable but not the hotel’s fault. Every available amenity like laundry and luggage holding was an extra 5 Euro which felt a bit excessive (5 for wash, another 5 to dry)."
Reviewed on 13 Sept 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Santo Spirito Travel Guide
- Places of interest
- Hotels in Santo Spirito by Star Rating
- Choose Your Santo Spirito Hotel Style
- Hotels in top Florence neighborhoods
- Search Santo Spirito Hotel Brands
- Piazza Santo Spirito
- Santo Spirito Basilica
- Church of St Felix
- Il Nabucco di Matteo Gabellini
- Uffizi Gallery
- Cathedral of Santa Maria del Fiore
- Piazza di Santa Maria Novella
- Piazza del Duomo
- Piazza della Signoria
- Palazzo Vecchio
- Pitti Palace
- Mugello Circuit
- Piazzale Michelangelo
- Gallery of the Academy of Florence
- Basilica of Santa Maria Novella
- Central Market
- Fortezza da Basso
- Antinori nel Chianti Classico
- The Mall Luxury Outlet
- Arno River
- Careggi Hospital
- Piazza San Marco
- Basilica of Santa Croce
- Boboli Gardens
Choose Your Santo Spirito Hotel Style
- Adults Only Resorts & Hotels in Santo Spirito
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