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Our top choices for La Mesa hotels with suites

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Best Western Plus La Mesa San Diego

Best Western Plus La Mesa San Diego

2.5 star property
La Mesa
8.2 out of 10, Very good, (1001)
"Clean room, great breakfast, pleasant staff. It was comfortable. "
United States
Vonda
The price is 2.555.517 ₫
2.811.068 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus La Mesa San Diego
Blackout curtains, free WiFi, bed sheets
Motel 6 La Mesa, CA - San Diego

Motel 6 La Mesa, CA - San Diego

2.0 star property
La Mesa
7.4 out of 10, Good, (976)
"Best Motel 6 I’ve ever been too! Clean marbel showers and comfortable beds!"
United States
Izaiah
The price is 2.266.868 ₫
2.497.509 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Motel 6 La Mesa, CA - San Diego
Outdoor pool, pool umbrellas, pool loungers
Heritage Inn La Mesa

Heritage Inn La Mesa

2.0 star property
La Mesa
7.0 out of 10, Good, (1197)
"room was clean and staff very friendly"
United States
Charles
The price is 1.502.293 ₫
1.657.795 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Heritage Inn La Mesa
Suite, Multiple Beds, Kitchenette | Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Holiday Inn Express La Mesa Near SDSU by IHG

Holiday Inn Express La Mesa Near SDSU by IHG

3.0 star property
La Mesa
8.2 out of 10, Very good, (449)
"Very accommodating "
United States
Todd
The price is 3.558.870 ₫
3.921.697 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Holiday Inn Express La Mesa Near SDSU by IHG
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillow-top beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (725)
"Great little boutique hotel ! Friendly staff as well"
Canada
Caroll
The price is 2.577.892 ₫
2.988.937 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The DEXTRO Little Italy, BW Premier Collection
3 outdoor pools, pool cabanas (surcharge), pool umbrellas
Sycuan Casino Resort

Sycuan Casino Resort

4.0 star property
El Cajon
9.2 out of 10, Wonderful, (1634)
"Nice hotel and friendly staff. Will definitely stay again ."
United States
Lorna
Sycuan Casino Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

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Frequently asked questions

How much do hotels with suites in La Mesa cost?
Hotels with suites in La Mesa range between 1.657.795 ₫ and 5.993.859 ₫ per night. With deals like these, you can enjoy roomy accommodation without having to pay a premium. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best hotels with suites in La Mesa?
Choose from multiple hotels with suites in La Mesa that have a total average guest review rating of 8.3. Staypineapple, Hotel Z, Gaslamp San Diego is an excellent choice if you're searching for a place to stay with a little extra space. This highly rated 3-star getaway also offers pillow top mattresses and designer toiletries. Moxy San Diego Downtown/Gaslamp Quarter is another recommended option with suites. It has a 3.5-star rating and handy amenities such as WiFi and front desk services.
What are the best cheap hotels with suites in La Mesa?
Hotels with suites start from 1.657.795 ₫ per night, so your La Mesa holiday doesn't have to break the bank! Hampton Inn Chula Vista Eastlake is a wallet-friendly stay that has plenty of amenities, such as an outdoor entertainment area and pool sun loungers. Hampton Inn San Diego-Kearny Mesa is another affordable option with suite rooms. Conveniences here include individually decorated rooms and designer toiletries. If you want to hold on to your hard-earned cash and still see the best of La Mesa, add some awesome free attractions to your must-do list. Mount Helix Park and Convoy District will keep you busy. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels with suites in La Mesa?
Travelling with the family in La Mesa is easy at Staypineapple, Hotel Z, Gaslamp San Diego. Offering suite rooms and amenities like nearby whale-watching activities and pillow top mattresses, your whole crew will enjoy their space at this 3-star stay. Marriott Holiday Club®, San Diego is another family-friendly hotel offering this upgraded class of accommodation. It has a 3.5-star rating and conveniences including a nearby theme park and WiFi. After checking in and chilling together in your comfortable new digs, it's time to head out and start sightseeing. San Diego Zoo and San Diego Natural History Museum are some of the best family-friendly attractions in La Mesa.
Are there any 5-star hotels with suites in La Mesa?
Pendry San Diego is a popular 5-star hotel with suites in La Mesa. Around 14 km from the downtown area, a swimming pool and a rooftop terrace are among the amenities here. THE US GRANT, a Luxury Collection Hotel, San Diego is another high-end retreat around 14 km from the centre of the city. This 5-star property offers suites with that extra space for you to stretch out, as well as Egyptian-cotton sheets and pillow top mattresses.
Why book your hotel with suites in La Mesa with Expedia?
Whatever your budget or desires, we'll help you find your ideal hotel with suites in La Mesa. Keep things affordable and choose a property with a lower star rating, or splurge on a high-end hotel and really stretch out in your suite in style. Use our search filters to narrow your results and score an incredible deal.
How can I find cheap hotels with suites in La Mesa?
To score an amazing hotel deal, use the filters to fine-tune your search. Start by sorting your results by price so that the most affordable options appear at the top of the list. Then, set the price-per-night filter to suit your budget. Ready to enjoy the "suite" life? Your ideal cheap La Mesa hotel with suites is right here on Expedia.
What is there to do in La Mesa near my hotel with suites?
If you want to explore the sights of La Mesa, make your way to Computer Museum of America. It's a favourite among locals and tourists alike.